Human EpCAM / TROP-1 / TACSTD1 Protein (ECD, His Tag) 10694-H08H from Sino Biological, Inc.

Product Specs
ItemHuman EpCAM / TROP-1 / TACSTD1 Protein (ECD, His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10694-H08H
Size100 µg
Conjugate/TagC-His
Purity> 96 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Activity1.Measured by the ability of the immobilized protein to support the adhesion of NIH-3T3 mouse embryonic fibroblast cells (Routinely tested). 2.Immobilized Recombinant Human EpCAM / TROP-1 / TACSTD1 Protein (ECD, His Tag) (Cat: 10694-H08H) at 1 µg/mL (100 µL/well) can bind anti-EpCAM scFv-hIgG1 Fc, the EC50 is 0.2-1.0 ng/mL (QC tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human EpCAM consists of 253 amino acids after removal of the signal peptide and has a calculated molecular mass of 28.84 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of human EpCAM is approximately 36.5 kDa due to glycosylation
SpeciesHuman
Molecule NameEpCAM
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameepithelial cell adhesion molecule
NCBI Gene AliasesBer-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) ImmunoPET imaging of EpCAM in solid tumours with nanobody tracers: a preclinical studyEuropean journal of nuclear medicine and molecular imagingJanuary 1, 2025Xu D, Zhang Y, Huang W, Pan X, An S, Wang C, Huang G, Liu J, Wei W.

(2) Trop-2 expression in non-small cell lung cancerPloS oneJanuary 1, 2025Kuo P, Elboudwarej E, Zavodovskaya M, Lin KW, Lee CV, Diehl L, Patel J, Mekan S, Jürgensmeier JM.immuno 96-well plates (Thermo Fisher) were coated with 1ug/ml Trop-2 or EPCAM (Sino Biological Cat# 10694-H08H) in PBS. Serial dilutions of anti–Trop-2 antibodies were added to antigen coated plates for 1-hour binding

(3) Novel Anti-Trop2 Nanobodies Disrupt Receptor Dimerization and Inhibit Tumor Cell GrowthPharmaceuticsSeptember 27, 2024Junwen Deng, Zhongmin Geng, Linli Luan, Dingwen Jiang, Jian Lu, Hanzhong Zhang, Bingguan Chen, Xinlin Liu, Dongming Xingdetection. 2.7. ELISA The 96-well NUNC microplates were coated with Trop2-ECD, EpCAM (Sino Biological, 10694-H08H) and another related antigen overnight at 4 °C. The solution in the well was then discarded and 2% milk

(4) An aptamer-guided fluorescence polarisation platform for extracellular vesicle liquid biopsyJournal of extracellular vesiclesSeptember 1, 2024Pham CV, Chowdhury R, Patel S, Jaysawal SK, Hou Y, Xu H, Jia L, Zhang YM, Wang X, Duan W, et al.protein was established by the addition of 100 µL of 50 nM free EpCAM protein (Sino Biological, Cat. No.: 10694‐H08H). Other controls with EpCAM‐negative or HER2‐negative EVs were prepared using the same concentration

(5) Detection of Hepatocellular Carcinoma in an Orthotopic Patient-Derived Xenograft with an Epithelial Cell Adhesion Molecule-Specific PeptideCancersAugust 10, 2024Wu X, Feng S, Chang TS, Zhang R, Jaiswal S, Choi EK, Duan Y, Jiang H, Wang TD.against the extra-cellular domain (ECD) of purified EpCAM protein (Sino Biological Inc., Beijing, China, #10694-H08H) for 4 rounds [29]. A total of 100, 80, 60, and 40 μg of EpCAM ECDs were used for each successive round

(6) A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapyMAbsMarch 6, 2024Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Shortimmunizing mice with a huEpCAM hexa-histidine-tagged ECD (huEpCAM ECD-His, Sinobiological catalog no. 10694-H08H). The hybridoma clones were screened for binding to recombinant huEpCAM ECD-His and CHO cells (RRID:CVCL_0213)

(7) In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimersProceedings of the National Academy of Sciences of the United States of AmericaApril 14, 2020Bell DR, Weber JK, Yin W, Huynh T, Duan W, Zhou R.conformations. EpCAM Reagents. Human EpCAM protein was purchased from Sino Biological Inc. Australia (catalog number: 10694-H08H). EP23 aptamer: 5′-A (2′-F-C) G (2′-F-U) A (2′-F-U) (2′-F-C) (2′-F-C) (2′-F-C) (2′F-U) (2′-F-U) (2′-F-U)

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Human EpCAM / TROP-1 / TACSTD1 Protein (ECD, His Tag)

Human EpCAM / TROP-1 / TACSTD1 Protein (ECD, His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human EpCAM / TROP-1 / TACSTD1 Protein (ECD, His Tag) from Sino Biological, Inc.

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