Human CD64 / FCGR1A Protein (ECD, His Tag) 10256-H08S from Sino Biological, Inc.

Product Specs
ItemHuman CD64 / FCGR1A Protein (ECD, His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10256-H08S
Size100 µg
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. ≥ 90 % as determined by SEC-MALS(Routinely tested)
Activity1.Immobilized Anti-CD20 (Research Grade Rituximab Biosimilar) at 1 µg/mL (100 µL/well) can bind Recombinant Human CD64 / FCGR1A Protein (ECD, His Tag)(Cat:10256-H08S), the EC50 0.7-2.1 ng/mL(QC tested). 2.Loaded Herceptin on ProA Biosensor, can bind Recombinant Human CD64/FCGR1 Protein, His Tag (Cat. No. 10256-H08S) with an affinity constant of 1.73 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Loaded Recombinant Human CD64/FCGR1 Protein, His Tag (Cat. No. 10256-H08S) on HIS1K Biosensor, can bind Herceptin with an affinity constant of 11.1 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 4.Anti-CD20 (Research Grade Rituximab Biosimilar) captured on Protein A chip can bind Recombinant Human CD64/FCGR1 Protein, His Tag (Cat. No. 10256-H08S) with an affinity constant of 69.3 pM as determined in an SPR assay (Biacore 8K) (Routinely tested). 5.Recombinant Human CD64 / FCGR1A Protein (ECD, His Tag) (Cat: 10256-H08S) captured on CM5 chip via Anti-His antibody, can bind anti-ERBB2(Research grade trastuz*mab biosimilar) with an affinity constant of 2.250 nM as determined in an SPR assay (Biacore 8K) (QC tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human FCGR1A consists of 284 amino acids and predicts a molecular mass of 32 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the recombinant human FCGR1A is approximately 45-60 kDa due to glycosylation. The molecular weight of this protein is around 46 kDa verified by SEC-MALS (Routinely tested)
SpeciesHuman
Molecule NameFCGR1
Source/Expression SystemCHO Stable Cells
NCBI Full Gene NameFc gamma receptor Ia
NCBI Gene AliasesCD64, CD64A, FCG1, FCGR1, FCRI, FcgammaRI, IGFR1

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Non-Glycosylated, Legumain-Cleavable ISACs Drive Potent Anti-Tumor Immunotherapy via a Bystander EffectMolecular Cancer TherapeuticsApril 2, 2026Anqi Zhang, Mohan Reddy Mullapudi, Lina Wu, Michele Yi, Mohammad Asikur Rahman, Aiman A. Yaseen, H. Kayla Zhong, Tracy A. Brooks, L. Nathan Tumeyanalysis Histidine-tagged FcγR proteins were obtained from commercial suppliers: CD64 (FcγRI, Sino Biological, cat. #10256-H08S-100), CD16a (FcγRIIIa, Invitrogen, cat. #RP87975), and CD32a (FcγRIIa, Sino Biological, cat. #10374-H08H1-100).

(2) Nonglycosylated, Legumain-Cleavable ISACs Drive Potent Antitumor Immunotherapy via a Bystander EffectMol Cancer TherDecember 30, 2025Anqi Zhang, Mohan Reddy Mullapudi, Lina Wu, Michele Yi, Mohammad Asikur Rahman, Aiman A. Yaseen, H. Kayla Zhong, Tracy A. Brooks, L. Nathan Tumeyanalysis Histidine-tagged FcγR proteins were obtained from commercial suppliers: CD64 (FcγRI, Sino Biological, cat. #10256-H08S-100), CD16a (FcγRIIIa, Invitrogen, cat. #RP87975), and CD32a (FcγRIIa, Sino Biological, cat. #10374-H08H1-100).

(3) Preclinical investigations and a first-in-human phase 1a trial of JS007, a novel anti-CTLA-4 antibody, in patients with advanced solid tumorsExperimental hematology & oncologyOctober 1, 2024Zhou C, Jiang J, Xiang X, Liu H, Wu G, Zeng R, Lu T, Zhang M, Shen Y, Hong M, et al.Biomedical, 20200421), FcγRIIa (CD32a) R167 (Sino Biological, 10734-H08C), FcγRI (CD64) (Sino Biological, 10256-H08S), and FcRn (Sino Biological, CT009-H08H). The test antibody was then gradient-diluted, and binding signals

(4) Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal AntibodiesAntibodies (Basel, Switzerland)November 8, 2021Noy-Porat T, Edri A, Alcalay R, Makdasi E, Gur D, Aftalion M, Evgy Y, Beth-Din A, Levy Y, Epstein E, et al.tested using ELISA. CD16 (CatNo. 4325-FC-050, R&D Systems, Minneapolis, MN, USA) and CD64 (Cat No. 10256-H08S, Sino Biological, Beijing, China) were used to coat 96-well plates at 2 µg/mL. For CD16, the plate was

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Human CD64 / FCGR1A Protein (ECD, His Tag)

Human CD64 / FCGR1A Protein (ECD, His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human CD64 / FCGR1A Protein (ECD, His Tag) from Sino Biological, Inc.

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