Mouse HMGB1 / HMG1 Protein (Fc Tag) 50913-M01H from Sino Biological, Inc.

Product Specs
ItemMouse HMGB1 / HMG1 Protein (Fc Tag)
CompanySino Biological, Inc.
Price $258.00Supplier Page View Company Product Page
Catalog Number50913-M01H
Conjugate/TagN-human IgG1-Fc
Purity> 85 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant mouse HMGB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 475 amino acids and has a calculated molecular mass of 53.3 kDa. The apparent molecular mass of the monomer is approximately 57 kDa in SDS-PAGE under reducing conditions
SpeciesMouse
Molecule NameHMGB1
Source/Expression SystemHEK293 Cells
ActivityMeasured by its ability to bind mouse AGER-His in functional ELISA
FormatLyophilized from sterile PBS, pH 7.4
Size50 µg

Add to Compare List

Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) CRISPLD2 protects against liver inflammation and fibrosis via GRP78 to repress HMGB1/TLR4 axis-mediated STING palmitoylationHepatology communicationsMay 1, 2026Zhang H, Wang J, Yang H, Yan Y, Zou J, Liu Z.containing 10% FBS. The primary hepatocytes were treated with 5 μg/mL recombinant mouse HMGB1 protein (50913-M01H; Sino Biological, Beijing, China) for 3, 9, 18, 24, and 48 hours or 1, 5, 10, and 20 μg/mL recombinant

(2) CRISPLD2 protects against liver inflammation and fibrosis via GRP78 to repress HMGB1/TLR4 axis-mediated STING palmitoylationHepatol CommunMay 1, 2026Haoye Zhang, Juan Wang, Hui Yang, Yu Yan, Jiafeng Zou, Zhenguo Liucontaining 10% FBS. The primary hepatocytes were treated with 5 μg/mL recombinant mouse HMGB1 protein (50913-M01H; Sino Biological, Beijing, China) for 3, 9, 18, 24, and 48 hours or 1, 5, 10, and 20 μg/mL recombinant

(3) A poorly reactogenic lipid nanoparticle-mRNA vaccine unveils an innate immune pathway for adverse reactionsnpj VaccinesApril 16, 2026Tomohiro Takano, Keigo Kumagai, Hitoshi Iuchi, Kazutaka Terahara, Aya Mizuike, Eita Sasaki, Yu Adachi, Ryutaro Kotaki, Saya Moriyama, Shinichiro Ota, et al.well in 96-well U-bottom plates (TPP, #92097) and stimulated with recombinant HMGB1 (Sino Biological, #50913-M01H) at 1 or 5 µg/mL, or left unstimulated. Cells were incubated for 2 h at 37 °C in 5% CO2, after which

(4) Berberine Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulating the AMPK-HMGB1-NF-κB Signaling AxisFrontiers in bioscience (Landmark edition)January 23, 2026Lv T, Zhang C, Zeng Y, Hu L, Huang G, Wang C, Qi W.

(5) Hydrogen-releasing magnesium hydrogel mitigates post laminectomy epidural fibrosis through inhibition of neutrophil extracellular trapsActa biomaterialiaOctober 15, 2024Mei R, Sun J, Cao S, Shi M, Song Z, Hua F, Zhou G, Zhang M, Liu J.

(6) Rab26 alleviates sepsis-induced immunosuppression as a master regulator of macrophage ferroptosis and polarization shiftFree radical biology & medicineFebruary 20, 2024Gong D, Liu X, Wu P, Chen Y, Xu Y, Gao Z, Qian H, Wang G, He B.

(7) Substance P promotes epidural fibrosis via induction of type 2 macrophagesNeural Regeneration ResearchApril 14, 2023Ming-Shun Zhang, Hao-Ran Wang, Yun-Feng Hua, Jin-Peng Wang, Yun-Feng Wang, Jin-Peng Sun, Ming-Shun Zhang, Ying Liua 24-well culture plate, they were stimulated with 10 ng/mL high mobility group box 1 (HMGB1; Cat# 50913-M01H, SinoBiological, Beijing, China) for 24 hours. Flow cytometry was used to detect β3-tubulin, a marker

(8) CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantationJ Clin InvestJuly 15, 2022Melissa Querrey, Stephen Chiu, Emilia Lecuona, Qiang Wu, Haiying Sun, Megan Anderson, Megan Kelly, Sowmya Ravi, Alexander V. Misharin, Daniel Kreisel, et al.(Sigma-Aldrich, SML0196), ODN 1826 (InvivoGen, tlrl-1826), and HMGB1 Protein, Mouse Recombinant (SinoBiological, 50913-M01H). All agonists were dosed at 1 μg. LA-1 and glycyrrhizin mentioned above were used at 20 μM concentration

(9) CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantationJournal of Clinical InvestigationJuly 15, 2022Melissa Querrey et al.(Sigma-Aldrich, SML0196), ODN 1826 (InvivoGen, tlrl-1826), and HMGB1 Protein, Mouse Recombinant (SinoBiological, 50913-M01H). All agonists were dosed at 1 μg. LA-1 and glycyrrhizin mentioned above were used at 20 μM concentration

(10) Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarizationJournal of experimental & clinical cancer research : CRFebruary 22, 2022Li Z, Fu WJ, Chen XQ, Wang S, Deng RS, Tang XP, Yang KD, Niu Q, Zhou H, Li QR, et al.(rhHMGB1, No.1690-HMB-050) was purchased from R&D Systems and recombinant mouse HMGB1 (rmHMGB1, Cat. 50913-M01H) was from Sino Biological. qRT-PCR qRT-PCR was performed as previously described [16]. The specific

(11) Extracellular HMGB1 Impairs Macrophage-Mediated Efferocytosis by Suppressing the Rab43-Controlled Cell Surface Transport of CD91Frontiers in immunologyJanuary 1, 2022Wang Y, Zhang W, Xu Y, Wu D, Gao Z, Zhou J, Qian H, He B, Wang G.Antibodies The reagents used for the study were as follows: rHMGB1 (Sino Biological, Beijing, China; #50913-M01H), CFDA SE Cell Proliferation Assay and Tracking Kit (Beyotime Biotechnology, Shanghai, China; #C0051),

(12) Metformin attenuates post-epidural fibrosis by inhibiting the TGF-β1/Smad3 and HMGB1/TLR4 signaling pathwaysJournal of cellular and molecular medicineApril 1, 2021Song Z, Wu T, Sun J, Wang H, Hua F, Nicolas YSM, Kc R, Chen K, Jin Z, Liu J, et al.were stimulated with the following agents: 10 mmol/L metformin (D150959‐5G; Sigma), 250 ng/mL HMGB1 (50913‐M01H; Sino Biological), 10 ng/mL TGF‐β1 (100‐21‐10UG; PeproTech) and 1 ng/mL SRI‐011381 hydrochloride (Smad3

(13) HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosisClinical science (London, England : 1979)August 16, 2018Li J, Zeng C, Zheng B, Liu C, Tang M, Jiang Y, Chang Y, Song W, Wang Y, Yang C.

Be the First to Write a Review!

Mouse HMGB1 / HMG1 Protein (Fc Tag)

Mouse HMGB1 / HMG1 Protein (Fc Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (13)

Reviews

Mouse HMGB1 / HMG1 Protein (Fc Tag) from Sino Biological, Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map