Mouse CD80 / B7-1 Protein (Fc Tag) 50446-M02H from Sino Biological, Inc.

Product Specs
ItemMouse CD80 / B7-1 Protein (Fc Tag)
CompanySino Biological, Inc.
Price $248.00Supplier Page View Company Product Page
Catalog Number50446-M02H
Conjugate/TagC-human IgG1-Fc
Purity≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant mouse CD80 consists of 449 amino acids and has a predicted molecular mass of 50.7 kDa
SpeciesMouse
Molecule NameCD80
Source/Expression SystemHEK293 Cells
Activity1. Measured by its binding ability in a functional ELISA. 2. Immobilized human CTLA4 (cat: 11159-H08H) at 10 µg/mL (100 µl/well) can bind mouse CD80-Fc (cat: 50446-M02H), The EC50 of mouse CD80-Fc (cat: 50446-M02H) is 28 ng/mL
FormatLyophilized from sterile PBS, pH 7.4
NCBI Full Gene NameCD80 antigen
NCBI Gene AliasesB71, Cd28l, Ly-53, Ly53, MIC17, TSA1
Size100 µg

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Fax: 267-657-0217

Email: marketing@sinobiological.com

(1) Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immunotherapyScience translational medicineMarch 1, 2023Liu M, Wang X, Du X, Wu W, Zhang Y, Zhang P, Ai C, Devenport M, Su J, Muthana MM, et al.

(2) Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 AgentsCancer immunology researchDecember 1, 2021Assi HH, Wong C, Tipton KA, Mei L, Wong K, Razo J, Chan C, Howng B, Sagert J, Krimm M, et al.(Sino Biological, catalogs #10377-H02H and #50124-M02H), B7–1 (Sino Biological, catalogs #10698-H02H and #50446-M02H), CD137 (Sino Biological, catalogs #10041-H02H and #50811-M02H), OX40 (Sino Biological, catalogs #10481-H02H

Mouse CD80 / B7-1 Protein (Fc Tag)