Rat IL-1RA / IL1RN Protein (Fc Tag) 80073-R01H from Sino Biological, Inc.

Product Specs
ItemRat IL-1RA / IL1RN Protein (Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number80073-R01H
Size50 µg
Conjugate/TagN-human IgG1-Fc
Purity> 85 % as determined by SDS-PAGE
ActivityImmobilized rat IL1R1-His (Cat:80028-R08H) at 10 µg/ml (100 µl/well) can bind rat Fc-IL1RN, The EC50 of rat Fc-IL1RN is 5.1-11.9 ng/ml
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant rat IL1RN comprises 412 amino acids and predicts a molecular mass of 45.8 kDa. The apparent molecular mass of the recombinant protein is approximately 47 kDa in SDS-PAGE under reducing conditions due to glycosylation
SpeciesRat
Molecule NameIL1RN
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinterleukin 1 receptor antagonist
NCBI Gene AliasesIL-1ra

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(1) Inhibition of MLKL-dependent necroptosis via downregulating interleukin-1R1 contributes to neuroprotection of hypoxic preconditioning in transient global cerebral ischemic ratsJournal of neuroinflammationApril 20, 2021Zhan L, Lu X, Xu W, Sun W, Xu E.of 0.3 μl/min. A total of 10 μl volume of IL-1RA (0.15 mmol/L, Sino Biological, Beijing, China, Cat# 80073-R01H) or the vehicle (sterile water) were administered bilaterally into the hippocampal CA1 region of rats

(2) Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic MacrophagesJournal of virologyAugust 17, 2020Wang ZY, Zhen ZD, Fan DY, Qin CF, Han DS, Zhou HN, Wang PG, An J.IL-1Ra-treated group were i.p. injected with 10 ␮g of a recombinant rat IL-1Ra (a natural IL-1␣ antagonist; 80073-R01H; Sino Biological) per mouse 1 h prior to i.p. injection with 104 PFU of JEV; then, an every-2-day i.p.

Rat IL-1RA / IL1RN Protein (Fc Tag)