Mouse IL-1 beta / IL1B Protein 50101-MNAE from Sino Biological, Inc.

Product Specs
ItemMouse IL-1 beta / IL1B Protein
CompanySino Biological, Inc.
Price $198.00Supplier Page View Company Product Page
Catalog Number50101-MNAE
Activity1. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 6-30 ng/mL
FormatLyophilized from sterile PBS, pH 7.4
Size20 µg
NCBI Gene AliasesIL-1beta, Il-1b
NCBI Full Gene Nameinterleukin 1 beta
Source/Expression SystemE. coli
Molecule NameIL1B
SpeciesMouse
Molecular WeightThe recombinant mouse IL1β consists of 153 amino acids and has a predicted molecular mass of 17.5 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions as predicted
TypeRecombinant protein
Purity≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Conjugate/TagUnconjugated

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Microglial serine racemase knockout alleviates Alzheimer-like neuropathology and behavioral deficit via lactylation-mediated anti-inflammationCommunications BiologyFebruary 25, 2026Jing Zhou, Yuanhong Yang, Shuyi Liu, Juan Chen, Hongji Liao, Wenjing Liang, Zhiwen Zhang, Yan Wang, Yimei Liu, He Zhang, et al.bovine serum (FBS) were purchased from Thermo Fisher Scientific (Shanghai, China). Mouse IL-1β (cat #50101-MNAE) was purchased from Sino Biological (Beijing, China). Srr−/− mice were created from Biocytogen through

(2) Targeted Blockage of Pathological Extracellular Vesicles and Particles From Fibroblast‐Like Synoviocytes for Osteoarthritis Relief: Proteomic Analysis and Cellular EffectJournal of Extracellular VesiclesSeptember 8, 2025Bin Liu, Yansi Xian, Tao Shen, Yu Ben, Wenshu Wu, Yong Shi, Xueying An, Rui Peng, Wentian Gao, Wang Gong, et al.Collections) supplemented with 10% FBS and 1% penicillin‐streptomycin. IL‐1β recombinant protein (10 ng/mL, 50101‐MNAE, SinoBiological) and bleomycin (25 µg/mL, T6116, Targetmol, USA) were employed to induce inflammation

(3) TIGIT deficiency promotes autoreactive CD4+ T-cell responses through a metabolic‒epigenetic mechanism in autoimmune myositisNat CommunMay 15, 2025Yimei Lai, Shuang Wang, Tingting Ren, Jia Shi, Yichao Qian, Shuyi Wang, Mianjing Zhou, Ryu Watanabe, Mengyuan Li, Xinyuan Ruan, et al.Cat# 50136-MNAE), IL-23 (30 ng/ml, NovoProtein, Cat# C03U), and IL-1β (20 ng/ml, Sino Biological, Cat# 50101-MNAE). Treg cells: anti-IFNγ antibody (5 μg/ml), anti-IL-4 antibody (5 μg/ml), TGFβ1 (5 ng/ml), and IL-2

(4) Comparative Effects of Monascin and Monascinol Produced by Monascus pilosus SWM-008 on Pro-Inflammatory Factors and Histopathological Alterations in Liver and Kidney Tissues in a Streptozotocin–Nicotinamide-Induced Rat ModelJournal of FungiNovember 25, 2024Pei-Xin Yang, Ya-Wen Hsu, Tzu-Ming Pan, Chun-Lin Leestandard protein (50136-MNAE), interleukin-1β (IL-1β) antibody (80023-RP02), and IL-1β standard protein (50101-MNAE) were purchased from Sino Biological Inc. (Beijing, China). Cyclooxygenase-2 (COX-2) antibody (12375-1-AP),

(5) Autophagy‐mediated activation of the AIM2 inflammasome enhances M1 polarization of microglia and exacerbates retinal neovascularizationMedComm (2020)August 1, 2024Xianyang Liu, Qian Zhou, Jiayu Meng, Hangjia Zuo, Ruonan Li, Rui Zhang, Huiping Lu, Zhi Zhang, Hongshun Li, Shuhao Zeng, et al.was purchased from TargetMol (T2154); recombinant protein IL‐1β was purchased from SinoBiological (50101‐MNAE); and Diacerein was purchased from Selleck (S4267). Rapamycin was purchased from MedChemExpress (HY‐10219).

(6) Myeloid Cell-Derived IL-1 Signaling Damps Neuregulin-1 from Fibroblasts to Suppress Colitis-Induced Early Repair of the Intestinal EpitheliumInternational journal of molecular sciencesApril 18, 2024Qiu D, Xu S, Ji K, Tang C.of 1 × 104 cells per well in 96-well plates supplemented with 0, 10, 50, and 100 ng/mL IL-1β (Cat# 50101-MNAE, Sino Biological, Beijing, China). After 24 h of treatment, colonic fibroblasts were harvested for RNA

(7) Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditisCell reportsNovember 8, 2022Won T, Kalinoski HM, Wood MK, Hughes DM, Jaime CM, Delgado P, Talor MV, Lasrado N, Reddy J, Čiháková D.210-12 Recombinant Mouse IL-23,Sino Biological,Cat# CT028-M08H Recombinant Mouse IL-1beta,Sino Biological,Cat# 50101-MNAE "Collagenase, Type 2",Worthington,Cat# LS004177 Deoxyribonuclease I,Worthington,Cat# LS002139 Hyaluronidase,MilliporeSigma,Cat#

(8) Gasdermin D–mediated pyroptosis suppresses liver regeneration after 70% partial hepatectomyHepatology CommunicationsSeptember 1, 2022Xingyu Lv, Jiang Chen, Jiayan He, Lidan Hou, Yiyue Ren, Xiaoyun Shen, Yifan Wang, Tong Ji, Xiujun Caiinhibitor Belnacasan (VX‐765; HY‐13205) were obtained from MedChemExpress. Recombinant mouse IL‐1β (50101‐MNAE) and IL‐18 (50073‐MNCE) were obtained from SinoBiological. Collagen type I (354236) was purchased from

(9) Madecassic acid alleviates colitis-associated colorectal cancer by blocking the recruitment of myeloid-derived suppressor cells via the inhibition of IL-17 expression in γδT17 cellsBiochemical pharmacologyAugust 1, 2022Yun X, Zhang Q, Fang Y, Lv C, Chen Q, Chu Y, Zhu Y, Wei Z, Xia Y, Dai Y.

(10) Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cellsNature communicationsJanuary 11, 2022Du Y, Peng Q, Cheng D, Pan T, Sun W, Wang H, Ma X, He R, Zhang H, Cui Z, et al.no. P0704L). Recombinant murine IL-1β and IL-23 proteins were bought from Sino Biological (cat no. 50101-MNAE and cat no. CT028-M08H). CellTrace™ CFSE Cell Proliferation Kit was bought from Invitrogen (cat no.

(11) Secreted frizzled-related protein 4 promotes brown adipocyte differentiationExperimental and therapeutic medicineJune 1, 2021Guan H, Zheng H, Zhang J, Xiang A, Li Y, Zheng H, Xu L, Liu E, Yu Q.were treated with recombinant mouse SFRP4 (cat. no. 50053-M08H; 1, 10 or 100 ng/ml) or IL-1β (cat. no. 50101-MNAE; 25 ng/ml) active protein (Sino Biological Company) at the dedicated time points as described previously

(12) MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarizationCell reportsFebruary 2, 2021Yuan Q, Gu J, Zhang J, Liu S, Wang Q, Tian T, Chen Z, Zhang J.

(13) Interleukin-1β Suppresses Gastrin via Primary Cilia and Induces Antral HyperplasiaCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Ding L, Sontz EA, Saqui-Salces M, Merchant JL.GLUTag subclone at 40%–60% confluency was treated with low-dose (5 ng/mL) or high-dose (10 ng/mL) IL1β (#50101-MNAE, SinoBiological, Chesterbrook, PA); low-dose (200 U/mL) or high-dose (800 U/mL) IFN-γ (#PMC4031, Thermo Fisher

(14) Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activationCancer lettersMarch 1, 2020Shen L, Kang L, Wang D, Xun J, Chen C, Du L, Zhang M, Gong J, Mi X, Yue S, et al.

(15) Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot SpecificityCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Guan H, Zhang Y, Gao S, Bai L, Zhao S, Cheng XW, Fan J, Liu E.

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Mouse IL-1 beta / IL1B Protein

Mouse IL-1 beta / IL1B Protein from Sino Biological, Inc.

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Sino Biological, Inc.

Citations (15)

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Mouse IL-1 beta / IL1B Protein from Sino Biological, Inc.

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