Mouse LDLR / LDL Receptor Protein (His Tag) 50305-M08H from Sino Biological, Inc.

Product Specs
ItemMouse LDLR / LDL Receptor Protein (His Tag)
CompanySino Biological, Inc.
Price $1,288.00Supplier Page View Company Product Page
Catalog Number50305-M08H
Conjugate/TagC-His
Purity≥ 90 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe secreted recombinant mouse LDLR comprises 780 amino acids with a predicted molecular mass of 85.7 kDa. As a result of glycosylation, it migarates as approximately 120-130 kDa protein in SDS-PAGE under reducing conditions
SpeciesMouse
Molecule NameLDLR
Source/Expression SystemHEK293 Cells
NCBI Full Gene Namelow density lipoprotein receptor
NCBI Gene AliasesHlb301
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Rat PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant mouse LDLR. The EC50 of biotinylated mouse LDLR is 0.173 µg/ml
FormatLyophilized from sterile PBS, pH 7.4
Size500 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Binding of Macrophage Receptor MARCO, LDL, and LDLR to Disease-Associated Crystalline StructuresFrontiers in immunologyJanuary 1, 2020Alberts A, Klingberg A, Hoffmeister L, Wessig AK, Brand K, Pich A, Neumann K.(Sino Biological, #10231-H08H-50), human CD32b (Sino Biological, #10259-H08H), and murine LDLR (Sino Biological, #50305-M08H). After washing with HBSS, bound proteins were detected at 4°C for 30 min using PE mouse anti-His Tag

(2) Identification and characterization of highly versatile peptide-vectors that bind non-competitively to the low-density lipoprotein receptor for in vivo targeting and delivery of small molecules and protein cargosPloS oneJanuary 1, 2018David M, Lécorché P, Masse M, Faucon A, Abouzid K, Gaudin N, Varini K, Gassiot F, Ferracci G, Jacquot G, et al.

(3) Optimization and in Vivo Validation of Peptide Vectors Targeting the LDL ReceptorMolecular pharmaceuticsDecember 5, 2016Jacquot G, Lécorché P, Malcor JD, Laurencin M, Smirnova M, Varini K, Malicet C, Gassiot F, Abouzid K, Faucon A, et al.

(4) Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytesThe Journal of biological chemistryApril 20, 2012Basak JM, Verghese PB, Yoon H, Kim J, Holtzman DM.

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Mouse LDLR / LDL Receptor Protein (His Tag)

Mouse LDLR / LDL Receptor Protein (His Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

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Mouse LDLR / LDL Receptor Protein (His Tag) from Sino Biological, Inc.

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