Mouse EGF / Epidermal Growth Factor Protein 50482-MNCH from Sino Biological, Inc.

Product Specs
ItemMouse EGF / Epidermal Growth Factor Protein
CompanySino Biological, Inc.
Price $78.00Supplier Page View Company Product Page
Catalog Number50482-MNCH
Activity1.Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.1-0.6 ng/mL. 2.Human intestinal cancer organoids were cultured with RSPO1(Cat#11083-HNAS), EGF(Cat#50482-MNCH), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology. 3.Human colorectum organoids were cultured with RSPO1(Cat#11083-HNAS), EGF(Cat#50482-MNCH), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology. 4.Human lung cancer organoids were cultured with FGF2(Cat#10014-HNAE), FGF4(Cat#16043-HNAE), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 5.Human lung organoids were cultured with FGF2(Cat#10014-HNAE), FGF4(Cat#16043-HNAE), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 6.Human cholangiocarcinomas organoids were cultured with FGF2(Cat#10014-HNAE), HGF(Cat#10463-HNAS), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 7.Human liver cancer organoids were cultured with FGF2(Cat#10014-HNAE), HGF(Cat#10463-HNAS), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), TGFB1(Cat#10804-HNAC), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 8.Human kidney cancer organoids were cultured with FGF2(Cat#10014-HNAE), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 9.Human kidney organoids were cultured with FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS), HGF(Cat#10463-HNAS), FGF4(Cat#16043-HNAE). (Routinely tested). Data provided by D1 Medical Technology. 10.Human gastric cancer organoids were cultured with EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 11.Human stomach organoids organoids were cultured with EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 12.Human breast cancer organoids were cultured with FGF7(Cat#10210-H07E), RSPO1(Cat#11083-HNAS), IGF1(Cat#10598-HNAE), EGF(Cat#50482-MNCH), NRG1 Beta 1(Cat#11609-H01H), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology. 13.Human ovarian organoids were cultured with IGF1(Cat#10598-HNAE), NRG1 Beta 1(Cat#11609-H01H), RSPO1(Cat#11083-HNAS), EGF(Cat#50482-MNCH), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology. 14.Human small intestinal organoids were cultured with IL22(Cat#13059-HNAE), FGF10(Cat#10573-HNAE), EGF(Cat#50482-MNCH), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
NCBI Full Gene Nameepidermal growth factor
Source/Expression SystemHEK293 Cells
Molecule NameEGF
SpeciesMouse
Molecular WeightThe recombinant mouse EGF consists of 55 amino acids and predicts a molecular mass of 6.2 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity> 95 % as determined by SDS-PAGE
Conjugate/TagN-cleavage

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Dose response test of patient-derived cancer organoids to irradiationFrontiers in OncologyOctober 27, 2025Haina Yu, Canfeng Lin, Fan Chen, Lifeng Chen, Weizhen Liu, Hualong Liu, Jing Li, Ye Yao50688), 500 ng/mL R-spondin1 (Sino Biological, 11083-HNAS), 1% HEPES, 50 ng/mL EGF (Sino Biological, 50482-MNCH), 1% GlutaMAX, 1:500 gentamicin/amphotericin B (Gibco, R01510), 1:500 Normocin (InvivoGen, ant-nr-1),

(2) Comprehensive dissection of rectal cancer organoids in responses to chemoradiationCell Reports MedicineOctober 21, 2025Xiaoya Xu, Tao Lv, Ye Yao, Juefeng Wan, Lijun Shen, Fan Xia, Xiaoxue Gao, Yuanchuang Li, Guoxiang Fu, Yun Deng, et al.1,EnaMab,Cat# ERSP1000 Noggin,EnaMab,Cat# ENGG0100 Wnt3a,EnaMab,Cat# EWNT0100 EGF,Sino Biological,Cat# 50482-MNCH HEPES,Gibco,Cat# 15630080 Glutamax,Gibco,Cat# 35050061 Normocin,InvivoGen,Cat# ant-nr-1 Gentamicin/amphoteritin

(3) AF6 regulates intestinal IgA via crosstalk between intestinal epithelial cells and immune cells in inflammatory bowel diseaseiScienceJuly 18, 2025Liying Lu, Keying Xu, Huiheng Qu, Lele Song, Yanan Song, Yanjun Wu, Xia Sun, Jingwen Kong, Qian Wen, Jiazheng Jiao, et al.protein (hFc Tag),Sino Biological,Cat#50688-M02H Recombinant Mouse EGF protein,Sino Biological,Cat#50482-MNCH Y27632,Sigma,Cat#Y0503 Ionomycin,MCE,Cat#HY-13434 Phorbol 12-myristate 13-acetate,MCE,Cat#HY-18739 Brefeldin

(4) Protein phosphatase EYA1 regulates the dephosphorylation and turnover of BCL2L12 to promote glioma developmentInternational journal of biological sciencesJanuary 1, 2025Wei T, Lin R, Lu Y, Jin DY, Zhang J, Sham MH.medium. Tumorsphere medium consists of 500 ml DMEM/F12 (BI 01-172- 1ACS), 20 ng/ml EGF (Sino Biological 50482-MNCH), 10 ng/ml bFGF (Sino Biological 50037-M07E), 5 μg/ml insulin (Apexbio B7407), and 0.4% BSA (Sigma A4503).

(5) Characterizing the effects of triclosan and triclocarban on the intestinal epithelial homeostasis using small intestinal organoidsJournal of hazardous materialsNovember 5, 2024Cheng X, Shen H, Zhang W, Chen B, Xu S, Wu L.

(6) Protocol for the cryopreservation of Cryptosporidium isolates using enteroidsSTAR ProtocolsJune 21, 2024Miner Deng, Yanting Wei, Na Li, Lihua Xiao, Yaoyu Feng, Yaqiong Guoproteins" ,, Y-27632,Tocris,Cat#1254 GlutaMAX,Gibco,Cat#35050061 HEPES,Gibco,Cat#15630-808 Penicillin/Streptomycin,Gibco,Cat#15140122 N2,Gibco,Cat#A1370701 B27,Gibco,Cat#12587-0101 Gentamicin,Bioss,Cat#C7011 Fetal bovine serum (FBS),Gibco,Cat#10099-141 mEGF,Sino Biological,Cat#50482-MNCH Primocin,InvivoGen,Cat#ant-pm-1 Nicotinamide,Sigma,Cat#N0636 Matrigel,BD,Cat#356234 Gentle cell dissociation reagent

(7) Cultivation, cryopreservation, and transcriptomic studies of host-adapted Cryptosporidium parvum and Cryptosporidium hominis using enteroidsiScienceApril 19, 2024Miner Deng, Tianyi Hou, Jie Zhang, Xinjie Mao, Fuxian Yang, Yanting Wei, Yongping Tang, Wanting Zeng, Wanyi Huang, Na Li, et al.inhibitor,Tocris,Cat#1254 Glutamax,Gibco,Cat#35050061 HEPES,Gibco,Cat#15630-808 Penicillin/Streptomycin,Gibco,Cat#15140122 N2,Gibco,Cat#A1370701 B27,Gibco,Cat#12587-0101 Gentamicin,Bioss,Cat#C7011 mEGF,SinoBiological,Cat#50482-MNCH Primocin,InvivoGen,Cat#ant-pm-1 Nicotinamide,Sigma,Cat#N0636 Matrigel,BD,Cat#356234 Gentle Cell Dissociation Reagent

(8) ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylationScience advancesJune 2, 2023Jia M, Yue X, Sun W, Zhou Q, Chang C, Gong W, Feng J, Li X, Zhan R, Mo K, et al.protein was purified from Escherichia coli. Mouse EGF protein was obtained from Sino Biological Inc. (#50482-MNCH). Flag peptide was obtained from GenScript Biotech Corp. LDHA peptide (LGEHGDSSVPVWSGC) was synthesized

(9) Feedback activation of EGFR/wild-type RAS signaling axis limits KRAS(G12D) inhibitor efficacy in KRAS(G12D)-mutated colorectal cancerOncogeneMay 1, 2023Feng J, Hu Z, Xia X, Liu X, Lian Z, Wang H, Wang L, Wang C, Zhang X, Pang X.Nicotinamide (N0636, Sigma Aldrich), 10 nM Gastrin (G9145, Sigma Aldrich), 50 ng/mL recombinant human EGF (50482-MNCH, Sino Biological), 500 nM A83-01 (S7692, Selleck), 3 µM SB202190 (S1077, Selleck), 10 nM Prostaglandin E2

(10) Interleukin-33 Potentiates TGF-β Signaling to Regulate Intestinal Stem Cell Regeneration After Radiation InjuryCell transplantationJanuary 1, 2023Guan R, Pan M, Xu X, Du L, Rao X, Fu G, Lv T, Zhang L, Li Y, Tang P, et al.ng/mL, 11083-HNAS; Sino Biological Inc., Beijing, China), and epidermal growth factor (EGF) (50 ng/mL, 50482-MNCH; Sino Biological Inc., Beijing, China). A different concentration of murine recombinant IL-33 (PeproTech,

(11) Patient-Derived Organoid Model in the Prediction of Chemotherapeutic Drug Response in Colorectal CancerACS biomaterials science & engineeringAugust 8, 2022Hao M, Cao Z, Wang Z, Xin J, Kong B, Xu J, Zhang L, Chen P.

(12) Molecular Biomarker of Drug Resistance Developed From Patient-Derived Organoids Predicts Survival of Colorectal Cancer PatientsFrontiers in OncologyMarch 29, 2022Lifeng Chen, Bo Tian, Wen Liu, Haitao Liang, Yong You, Weizhen LiuNoggin (Sino Biological Inc., 50688-M02H), 50 ng/ml epidermal growth factor (EGF) (Sino Biological Inc., 50482-MNCH), 1 mM n-Acetylcysteine (Sigma-Aldrich, A9165), 10 mM Niacinamide (Sigma-Aldrich, N0636), 500 nM A8301

(13) Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathologyJournal of neuroinflammationFebruary 7, 2022Liu S, Fan M, Xu JX, Yang LJ, Qi CC, Xia QR, Ge JF.(04-001-1ACS, Biological Industries), 1% penicillin–streptomycin solution (C0222, Beyotime), 20 ng/mL EGF (50482-MNCH LC13JA1403, Sino Biological), and 20 ng/mL bFGF (50177-M08H LC12SE1702, Sino Biological). Isolation,

(14) Bach2 Deficiency Promotes Intestinal Epithelial Regeneration by Accelerating DNA Repair in Intestinal Stem CellsStem cell reportsJanuary 12, 2021Li Y, Rao X, Tang P, Chen S, Guo Q, Fu G, Pan M, Liang L, Yao Y, Gao X, et al.B27 (Gibco, 17504-044), 1 mM N-acetylcysteine (Sigma-Aldrich, A9165), 50 ng/mL EGF (Sino Biological, 50482-MNCH), 100 ng/mL Noggin (Sino Biological, 50688-M02H), and 500 ng/mL R-spondin1 (Sino Biological, 11083-HNAS).

(15) Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in miceAmerican journal of translational researchJanuary 1, 2019Guo Q, Chen S, Rao X, Li Y, Pan M, Fu G, Yao Y, Gao X, Tang P, Zhou Y, et al.

(16) Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathwayBiochimieAugust 1, 2016Zhang H, Nan W, Wang S, Zhang T, Si H, Wang D, Yang F, Li G.

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Organoid Technology in Drug Discovery
March 21, 2024
High-quality products are essential to culture, manipulate, and characterize these complex multicellular model systems read more

Mouse EGF / Epidermal Growth Factor Protein

Mouse EGF / Epidermal Growth Factor Protein

Mouse EGF / Epidermal Growth Factor Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Organoid Technology in Drug Discovery

Mouse EGF / Epidermal Growth Factor Protein from Sino Biological, Inc.

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