Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag) 50010-M03H from Sino Biological, Inc.

Product Specs
ItemMouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag)
CompanySino Biological, Inc.
Price $1,938.00Supplier Page View Company Product Page
Catalog Number50010-M03H
ActivityMeasured by its ability to bind mouse PD-1 in functional ELISA
FormatLyophilized from sterile PBS, pH 7.4
Size1 mg
Source/Expression SystemHEK293 Cells
Molecule NameCD274
SpeciesMouse
Molecular WeightThe recombinant mouse PD-L1/Fc is a disulfide-linked homodimeric protein after proteolytic removal of the signal peptide. The reduced monomer consists of 468 amino acids and predicts a molecular mass of 52.8 kDa. As a result of glycosylation, the apparent molecular mass of mouse PD-L1/Fc monomer is approximately 64-90 kDa in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity> 95 % as determined by SDS-PAGE
Conjugate/TagC-human IgG1-Fc, His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Radionuclide-stimulated dynamic therapy induces complementary immunogenic necroptosis and apoptosis cancer cell death pathwaysCommunications BiologyJanuary 19, 2026Christopher Egbulefu, Kvar Black, Xinming Su, Partha Karmakar, LeMoyne Habimana-Griffin, Gail Sudlow, Julie Prior, Ezugo Onejeme, Alex Zheleznyak, Baogang Xu, et al.Quality control standards included recombinant mouse purified proteins (#50502-M08B, #50124-M08H, #50010-M03H, #53069-M08H, Sinobiological, Wayne, PA, USA; and #752602, BioLegend, San Diego, CA, USA). Plasma samples

(2) The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-β and PD-L1Journal of hematology & oncologyFebruary 16, 2021Yi M, Zhang J, Li A, Niu M, Yan Y, Jiao Y, Luo S, Zhou P, Wu K.with TGF-β1 (Z03411, Genscript), TGF-β2 (Z03429, Genscript), TGF-β3 (Z03430, Genscript), and PD-L1 (50010-M03H, Sino Biological) (200 ng per well) at 4 °C overnight. On the next day, the plates were washed 3 times

(3) Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitorsEMBO molecular medicineJune 8, 2020Fan Z, Tian Y, Chen Z, Liu L, Zhou Q, He J, Coleman J, Dong C, Li N, Huang J, et al.μg/ml of aCD3/aCD28 and with culture media supplemented with mPD‐L1 protein (Fc tag, Sino Biological, 50010‐M03H‐10) in the presence of 100 nM of MB or 10 μg/ml of aPD1 antibody. Cells were stained with CD8‐PE (1:100,

(4) Depletion of PD-1-positive cells ameliorates autoimmune diseaseNature biomedical engineeringApril 1, 2019Zhao P, Wang P, Dong S, Zhou Z, Cao Y, Yagita H, He X, Zheng SG, Fisher SJ, Fujinami RS, et al.of αPD-1-ABD-PE. The PD-L1-Fc is a fusion protein between mouse PD-L1 and human Fc, Sino Biological, 50010-M03H). For concurrent incubation, the PD-L1-Fc was added to a final concentration of 500 nM with Alexa Fluor

(5) PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skinScientific reportsJanuary 25, 2018Miao X, Xu R, Fan B, Chen J, Li X, Mao W, Hua S, Li B.USA). In an intervention experiment using neutralizing mAb against PD-1, an mPD-L1 fusion protein (50010-M03H-200) was purchased from Sino Biological Inc. Mice were i.p. injected with 200 µg PD-L1 fusion protein

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Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag)

Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag) from Sino Biological, Inc.

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