Human TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag) 10465-H08H from Sino Biological, Inc.

Product Specs
ItemHuman TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag)
CompanySino Biological, Inc.
Price $248.00Supplier Page View Company Product Page
Catalog Number10465-H08H
Size100 µg
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Activity1.Loaded Recombinant Human DR5/TRAIL R2 Protein, His Tag (Cat. No. 10465-H08H) on HIS1K Biosensor, can bind Recombinant Human TRAIL/TNFSF10 Protein (Cat. No. 10409-HNAE) with an affinity constant of 0.122 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Immobilized Recombinant Human TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag) (Cat: 10465-H08H) at 2 µg/mL (100 µL/well) can bind biotinylated Recombinant Human TNFSF10 / TRAIL / APO-2L / CD253 Protein (Cat: 10409-HNAE-B), the EC50 is 1.0-3.0 ng/mL (QC tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human TNFRSF10B consists of 138 amino acids and has a predicted molecular mass of 15.7 kDa. As a result of glycosylation, the apparent molecular mass of rhTNFRSF10B is approxiamtely 20-22 kDa in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameTNFRSF10B
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameTNF receptor superfamily member 10b
NCBI Gene AliasesCD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) "Reply to ""Comment on 'Self-Illuminating Nanoagonist Simultaneously Induces Dual Cell Death Pathways via Death Receptor Clustering for Cancer Therapy'"""ACS nanoJanuary 14, 2025You Y, Wu X, Du YZ.

(2) DNA-based delivery of anti-DR5 Nanobodies improves exposure and anti-tumor efficacy over protein-based administrationCancer gene therapyAugust 1, 2021Vermeire G, De Smidt E, Casteels P, Geukens N, Declerck P, Hollevoet K.

(3) Designed ferritin nanocages displaying trimeric TRAIL and tumor-targeting peptides confer superior anti-tumor efficacyScientific reportsNovember 17, 2020Yoo JD, Bae SM, Seo J, Jeon IS, Vadevoo SMP, Kim SY, Kim IS, Lee B, Kim S.Reichert Inc., NY, USA) as described previously43. The extracellular region (1–182) of the DR5 protein (10465-H08H, Sino Biological, Beijing, China) was immobilized by activating the carboxymethyl group on dextran-coated

(4) HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis via Regulating DcR1 Expression Following Traumatic Brain InjuryFrontiers in cellular neuroscienceJanuary 1, 2020Fang Y, Lu J, Wang X, Wu H, Mei S, Zheng J, Xu S, Lenahan C, Chen S, Zhang J, et al.to mimic hypoxia (Zhong et al., 2017). Drug Administration sDR5 protein (Sino Biological, China, 10465-H08H) was used in vivo to block TRAIL-induced apoptosis (Cui et al., 2010). We injected 10 μg and 25 μg sDR5

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Human TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag)

Human TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag) from Sino Biological, Inc.

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