Human Urokinase / PLAU Protein (His Tag) 10815-H08H from Sino Biological, Inc.

Product Specs
ItemHuman Urokinase / PLAU Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10815-H08H
Conjugate/TagC-His
Purity≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe secreted recombinant human PLAU comprises 422 amino acids with a predicted molecular mass of 46 kDa. As a result of glycosylation, rhPLAU migrates as three bands corresponding to the long A chain, B chain and unprocessed full-length PLAU with the molecular mass of 18, 32 and 50 kDa respectively in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NamePLAU
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameplasminogen activator, urokinase
NCBI Gene AliasesATF, BDPLT5, QPD, UPA, URK, u-PA
Activity1.Immobilized human uPA at 5 µg/ml (100 µl/well) can bind mouse PLAUR with a linear range of 1.6-40 ng/ml(QC tested). 2.Recombinant Mouse PLAUR / CD87 / uPAR Protein (His Tag) (Cat: 50160-M08H) immobilized on CM5 chip, can bind Recombinant Human Urokinase / PLAU Protein (His Tag) (Cat: 10815-H08H) with an affinity constant of 8.340 nM as determined in an SPR assay (Biacore 8K) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size50 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Universal Fab-Fc masked cytokine prodrug platform: αPD-L1/IL-15 prodrug activates CD44+ CD8+ T cells in tumor-draining lymph nodes to enhance antitumor immunityJournal for ImmunoTherapy of CancerJuly 31, 2025Luyao Song, Gen Qi, Wenqiang Shi, Qiongya Zeng, Ying Qin, Zejian Wang, Wei Li, Zilan Song, Ao Zhang, Huili LuCat#20426ES80), Lymphocyte separation medium (DAKEWE, Cat#7211011), Urokinase/uPA (Sino Biological, Cat#10815-H08H), Human PD-L1 (Novoprotein, Cat#C315), tetramethylbenzidine (TMB) single component substrate solution

(2) Probiotic-mediated tumor microenvironment reprogramming with protease-sensitive interleukin-15 and photothermal therapyCell reports. MedicineJune 17, 2025Wang H, Zheng L, Yang C, Jia L, Zhou R, Liu H, Dong Y, Xu X, Shi G, Yang J, et al.proteins" ,, MMP2,Sino Biological,Cat#10082-HNAH MMP9,Sino Biological,Cat#10327-HNAH uPA,Sino Biological,Cat#10815-H08H p-aminophenylmercuric acetate,Sigma,Cat#A9563 IL-15,Abclonal,Cat#RP01676 EDC,Sigma,Cat# 39391 N-hydroxysuccinimide

(3) A tumor-conditional IL-15 safely synergizes with immunotherapy to enhance antitumor immune responsesMolecular therapy : the journal of the American Society of Gene TherapyDecember 4, 2024Shi W, Xu W, Song L, Zeng Q, Qi G, Qin Y, Li Z, Liu X, Jiao Z, Zhao Y, et al.

(4) Next-generation anti-PD-L1/IL-15 immunocytokine elicits superior antitumor immunity in cold tumors with minimal toxicityCell reports. MedicineMay 21, 2024Shi W, Liu N, Liu Z, Yang Y, Zeng Q, Wang Y, Song L, Hu F, Fu J, Chen J, et al.PD-L1,Novoprotein,Cat#: CJ88 Human PD-L1,Novoprotein,Cat#: C315 Urokinase/uPA,SinoBiological,Cat#: 10815-H08H Human MMP-2,SinoBiological,Cat#: 10082-HNAH CD122 (IL-2/15Rβ),SinoBiological,Cat#: 10696-H08B TMB

(5) Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancerScience advancesMay 27, 2022Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, Cai W, Wen F, Jiang X, Zhang T, et al.106 cells in 100 μl of staining buffer) was treated with 1 μg of His-tagged pro-uPA (Sino Biological, 10815-H08H) plus 1 μg of the anti-uPAR mAb in the dark at 4°C for 30 min. The other two groups, the untreated group

(6) Improved positron emission tomography imaging of glioblastoma cancer using novel ⁶⁸Ga-labeled peptides targeting the urokinase-type plasminogen activator receptor (uPAR)Amino acidsJune 1, 2017Loft MD, Sun Y, Liu C, Christensen C, Huang D, Kjaer A, Cheng Z.

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Human Urokinase / PLAU Protein (His Tag)

Human Urokinase / PLAU Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human Urokinase / PLAU Protein (His Tag) from Sino Biological, Inc.

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