Human TLR4 / CD284 Protein (His Tag) 10146-H08B from Sino Biological, Inc.

Product Specs
ItemHuman TLR4 / CD284 Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10146-H08B
Size100 µg
Conjugate/TagC-His
Purity≥ 87 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe secreted recombinant human TLR4 consists of 619 amino acids and predicts a molecular mass of 70.5 KDa. The apparent molecular mass of the protein is approximately 68 Kda in SDS-PAGE under reducing conditions due to glycosylation
SpeciesHuman
Molecule NameTLR4
Source/Expression SystemBaculovirus-Insect Cells
FormatLyophilized from sterile 20mM PB, 500mM NaCl, pH 6.0, 10% glycerol
NCBI Full Gene Nametoll like receptor 4
NCBI Gene AliasesARMD10, CD284, TLR-4, TOLL
Activity1.Immobilized Recombinant Human TLR4 / CD284 Protein (His Tag) (Cat: 10146-H08B) at 1 µg/mL (100 µl/well) on His Tag Antibody, Mouse MAb precoated (5 µg/mL, 100 µL/well) can bind Anti-TLR4 Antibody, the EC50 is 4-15 ng/mL (QC tested). 2.Immobilized Anti-TLR4 Antibody at 2 µg/mL (100 µL/well) can bind Recombinant Human TLR4 / CD284 Protein (His Tag) (Cat: 10146-H08B), the EC50 is 4-15 ng/mL (Routinely tested)

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) N-Terminal random curl-tandam α-helical peptide 7W: A potent antibacterial and anti-inflammatory dual-effect agent through tryptophan substitutionEuropean journal of medicinal chemistryAugust 5, 2025Lou J, Wu X, Ji W, Yu J, Xu Y, Xiao W, Lu W, Xin K, Chen T, Tang Q, et al.

(2) Oleuropein alleviates myocardial ischemia-reperfusion injury by suppressing oxidative stress and excessive autophagy via TLR4/MAPK signaling pathwayChinese medicineApril 8, 2024He J, Huang L, Sun K, Li J, Han S, Gao X, Wang QQ, Yang S, Sun W, Gao H.

(3) Use of Open Surface Plasmon Resonance (OpenSPR) to Characterize the Binding Affinity of Protein-Protein InteractionsBio-protocolSeptember 5, 2023Zhu CS, Li J, Wang H.reagents Reagents Extracellular domain of human TLR4 (residue 1-631, 70.5 kDa) (Sino Biological, catalog number: 10146-H08B)Extracellular domain of human RAGE (residue 1-344, 36.0 kDa) (Sino Biological, catalog number: 11629-H08H)Human

(4) Discovery of novel aporphine alkaloid derivative as potent TLR2 antagonist reversing macrophage polarization and neutrophil infiltration against acute inflammationActa Pharmaceutica Sinica BSeptember 1, 2023Junjie Yang, Yue Pan, Xiaoshan Zeng, Shuwen Liu, Zhipeng Chen, Kui Chengearlier11. The TLR2 protein was diluted with PBS to a concentration of 1 mg/mL and the TLR4 protein (10146-H08B, SinoBiological) was diluted with PBS to a concentration of 0.1 mg/mL. The 3D dextran chip was washed

(5) Multivalent Carbohydrate Nanocomposites for Tumor Microenvironment Remodeling to Enhance Antitumor ImmunityACS nanoJune 27, 2023Hyun GH, Jeong DH, Yang YY, Cho IH, Ha YJ, Xing X, Abbott DW, Hsieh YSY, Kang YP, Cha JH, et al.

(6) Coixol ameliorates Toxoplasma gondii infection-induced lung injury by interfering with T. gondii HSP70/TLR4/NF-κB signaling pathwayInternational immunopharmacologyMay 1, 2023Shen XY, Lu JM, Lu YN, Jin GN, Ma JW, Wang JH, Wang Y, Xu X, Piao LX.

(7) Gut microbial metabolite hyodeoxycholic acid targets the TLR4/MD2 complex to attenuate inflammation and protect against sepsisMolecular therapy : the journal of the American Society of Gene TherapyApril 5, 2023Li J, Chen Y, Li R, Zhang X, Chen T, Mei F, Liu R, Chen M, Ge Y, Hu H, et al.

(8) Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsisScience advancesFebruary 3, 2023Zhu CS, Qiang X, Chen W, Li J, Lan X, Yang H, Gong J, Becker L, Wang P, Tracey KJ, et al.instance, highly purified recombinant pCTS-L, human TLR4 (ECD-His Tag, residues 1 to 631, catalog no. 10146-H08B, Sino Biological Inc.), or extracellular domain of human RAGE (residues 1 to 344, catalog no. 11629-H08H,

(9) The soluble cytoplasmic tail of CD45 regulates T-cell activation via TLR4 signalingEuropean journal of immunologyDecember 1, 2021Puck A, Künig S, Modak M, May L, Fritz P, Battin C, Radakovics K, Steinberger P, Reipert BM, Crowe BA, et al.

(10) Towards automation in biologics production via Raman micro-spectroscopy, laser-induced forward cell transfer and surface-enhanced Raman spectroscopyJournal of biotechnologyNovember 10, 2020Jaeckle E, Brauchle E, Nottrodt N, Wehner M, Lensing R, Gillner A, Schenke-Layland K, Bach M, Burger-Kentischer A.

(11) Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4Scientific reportsApril 19, 2016Yang J, Qin N, Zhang H, Yang R, Xiang B, Wei Q.Ltd. (C05W206E), and TAK242 was from MCE (HY-11109). The recombinant extracellular domain of TLR4 (10146-H08B) and soluble CD14 10073-H007H) were purchased from Sino Biological, Inc. The following reagents were

(12) [17th issue dedicated to medical problems during the Nazi occupation. Foreward]Przeglad lekarskiJanuary 1, 1977Bogusz J.

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Human TLR4 / CD284 Protein (His Tag)

Human TLR4 / CD284 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human TLR4 / CD284 Protein (His Tag) from Sino Biological, Inc.

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