Rat PD-L1 / B7-H1 / CD274 Protein (Fc Tag) 80450-R02H from Sino Biological, Inc.

Product Specs
ItemRat PD-L1 / B7-H1 / CD274 Protein (Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number80450-R02H
ActivityMeasured by its binding ability in a functional ELISA. Immobilized rat CD274-Fc at 10 µg/ml (100 µl/well) can bind biotinylated rat PDCD1-Fc (Cat:80448-R02H), The EC50 of biotinylated rat PDCD1-Fc (Cat:80448-R02H) is 0.14-0.34 µg/ml
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
Source/Expression SystemHEK293 Cells
Molecule NameCD274
SpeciesRat
Molecular WeightThe recombinant rat CD274/Fc is a disulfide-linked homodimer. The reduced monomer comprises 459 amino acids and has a predicted molecular mass of 51.8 kDa. The apparent molecular mass of the protein is approximately 73.2 kDa in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity> 95 % as determined by SDS-PAGE
Conjugate/TagC-human IgG1-Fc

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(1) Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 AgentsCancer immunology researchDecember 1, 2021Assi HH, Wong C, Tipton KA, Mei L, Wong K, Razo J, Chan C, Howng B, Sagert J, Krimm M, et al.cynomolgus monkey PD-L1-Fc (Sino Biological, catalog #90251-C02H), and rat PD-L1-Fc (Sino Biological, catalog #80450-R02H); mouse PD-L1-Fc (R&D Systems, catalog #1019-B7) was coated on plates at 0.5 μg/mL. Plates were washed

Rat PD-L1 / B7-H1 / CD274 Protein (Fc Tag)