Human ABL1 / JTK7 / p150 Protein (GST Tag) 11199-H09B from Sino Biological, Inc.

Product Specs
ItemHuman ABL1 / JTK7 / p150 Protein (GST Tag)
CompanySino Biological, Inc.
Price $1,678.00Supplier Page View Company Product Page
Catalog Number11199-H09B
Conjugate/TagN-GST
Purity≥ 75 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human ABL1/GST chimera consists of 645 amino acids and predicts a molecular mass of 74 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameABL1
Source/Expression SystemBaculovirus-Insect Cells
NCBI Full Gene NameABL proto-oncogene 1, non-receptor tyrosine kinase
NCBI Gene AliasesABL, BCR-ABL, CHDSKM, JTK7, bcr/abl, c-ABL, c-ABL1, p150, v-abl
ActivityThe specific activity was determined to be>15 nmol/min/mg using synthetic Abl peptide (EAIYAAPFAKKK) as substrate
FormatSupplied as sterile 20mM Tris，300mM NaCl, 25% glycerol; 0.1mM PMSF, 0.1mM EDTA，0.5mM GSH，pH7.5
Size500 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosisbioRxivJune 16, 2025Manuel L. Merz, Veronika M. Shoba, Rajaiah Pergu, Zachary C. Severance, Dhanushka N. P. Munkanatta Godage, Arghya Deb, Hui Si Kwok, Prashant Singh, Sameek Singh, Jonathan B. Allen, et al.a maximum concentration of 1 μM. Next, TR-FRET assay buffer containing GST-ABL1 (Sino Biological, #11199-H09B, 2 nM), anti-GST nanobody conjugated to CoraFluor-1 (4 nM), and FITC-tracer (VS1231, 670 nM) were added,

(2) ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brainCell reportsAugust 30, 2022McKernan CM, Khatri A, Hannigan M, Child J, Chen Q, Mayro B, Snyder D, Nicchitta CV, Pendergast AM.#631231 DPH,Sigma,Cat #SML0202 GFP-Trap Agarose,Chromotek,Cat#gta-20 GST-ABL1 Recombinant Protein,Sino Biological,Cat#11199-H09B His-YB1 Recombinant Protein,Novus Biologicals,Cat#NBP2-30101 Staurosporine,Sigma,Cat#S6942 Anti-FLAG

(3) Discovery of Berberine that Targetedly Induces Autophagic Degradation of both BCR-ABL and BCR-ABL T315I through Recruiting LRSAM1 for Overcoming Imatinib ResistanceClinical cancer research : an official journal of the American Association for Cancer ResearchAugust 1, 2020Yin Z, Huang G, Gu C, Liu Y, Yang J, Fei J.

(4) In Situ Study of the Drug-Target Protein Interaction in Single Living Cells by Combining Fluorescence Correlation Spectroscopy with Affinity ProbesAnalytical chemistryMay 19, 2020Deng L, Huang X, Ren J.

(5) Simple and Sensitive Method for Determination of Protein Kinase Activity Based on Surface Charge Change of Peptide-Modified Gold Nanoparticles As SubstratesAnalytical chemistryMarch 20, 2018Yi F, Huang X, Ren J.

(6) Screening of break point cluster region Abelson tyrosine kinase inhibitors by capillary electrophoresisJournal of chromatography. AFebruary 16, 2018Xu M, Zheng M, Liu G, Zhang M, Kang J.

(7) A sensitive and microscale method for drug screening combining affinity probes and single molecule fluorescence correlation spectroscopyThe AnalystFebruary 21, 2015Ruan L, Su D, Shao C, Wang J, Dong C, Huang X, Ren J.