Human ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag) 11559-H08H from Sino Biological, Inc.

Product Specs
ItemHuman ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag)
CompanySino Biological, Inc.
Price $198.00Supplier Page View Company Product Page
Catalog Number11559-H08H
Size100 µg
Conjugate/TagC-His
Purity> 98 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC
Activity1.Immobilized Recombinant Human ICOS / AILIM / CD278 Protein (Fc Tag)(Cat:10344-H31H) at 2 µg/mL (100 µL/well) can bind Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag)(Cat:11559-H08H),The EC50 is 18-56 ng/mL(QC tested). 2.Immobilized Recombinant Human ICOS / AILIM / CD278 Protein (Fc Tag) (Cat: 10344-H02H) at 1 µg/mL (100 µL/well) can bind Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag) (Cat: 11559-H08H), the EC50 is 33.9 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe secreted recombinant human ICOSLG consists of 251 amino acids and has a calculated molecular mass of 28 kDa. The apparent molecular mass of the protein is approximately 42-62 kDa in SDS-PAGE under reducing conditions due to glycosylation
SpeciesHuman
Molecule NameICOSLG
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinducible T cell costimulator ligand
NCBI Gene AliasesB7-H2, B7H2, B7RP-1, B7RP1, B7h, CD275, GL50, ICOS-L, ICOSL, LICOS

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Discovery and characterization of two anti-PD-1 antibodies with a unique binding mechanism to human PD-1mAbsDecember 31, 2025Keyla María Gómez Castellano, Alejandra Montes Luna, Gregorio de Jesús Carballo Uicab, Frida Daniela Ramírez Villedas, Luis Javier Elizarrarás Rodríguez, Said Kayum Vázquez Leyva, Stefany Daniela Rodríguez Luna, Edith González González, María Martha Pedraza Escalona, Ben Holland, et al.Cat. No. 11524-HCCH), CTLA-4 (Sino Biological Cat. No. 11159-HNAH) or ICOS (Sino Biological Cat. No. 11559-H08H). Coated wells were washed with PBST and blocked with 3% BSA-PBS. UDIZ-007, UDIZ-008, and control antibodies

(2) Targeted degradation of sICOSL reverses cytotoxic T cells dysfunctionExperimental hematology & oncologyJuly 24, 2025Wu Z, Zheng P, Qi R, Xiao Y, Xi Z, Dai L, Chen T, Wang Q, Zhang F, Wang R, et al.cultured in RPMI 1640 or DMEM medium containing 10% fetal bovine serum. Cells were treated with sICOSL (11559-H08H; Sino Biological). Blood from healthy donors were obtained from the Wuhan Union Hospital with IRB approval

(3) Sr-Containing Mesoporous Bioactive Glasses Bio-Functionalized with Recombinant ICOS-Fc: An In Vitro StudyNanomaterials (Basel, Switzerland)January 27, 2021Fiorilli S, Pagani M, Boggio E, Gigliotti CL, Dianzani C, Gauthier R, Pontremoli C, Montalbano G, Dianzani U, Vitale-Brovarone C.

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Human ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag)

Human ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human ICOS Ligand / B7-H2 / ICOSLG Protein (ECD,His Tag) from Sino Biological, Inc.

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