Mouse PD1 / PDCD1 Protein (ECD,His Tag) 50124-M08H from Sino Biological, Inc.

Product Specs
ItemMouse PD1 / PDCD1 Protein (ECD,His Tag)
CompanySino Biological, Inc.
Price $278.00Supplier Page View Company Product Page
Catalog Number50124-M08H
FormatLyophilized from sterile PBS, pH 7.4
ActivityLoaded Recombinant Mouse PD-L1/B7-H1 Protein, hFc Tag (Cat. No. 50010-M02H) on ProA Biosensor, can bind Recombinant Mouse PD-1 Protein, His Tag (Cat. No. 50124-M08H) with an affinity constant of 3.6 µM as determined in BLI assay (Sartorius Octet RED384) (QC tested)
Size100 µg
NCBI Gene AliasesLy101, PD-1, Pdc1
NCBI Full Gene Nameprogrammed cell death 1
Source/Expression SystemHEK293 Cells
Molecule NamePDCD1
SpeciesMouse
Molecular WeightThe secreted recombinant mouse PDCD1 consists of 154 amino acids and has a predicted molecular mass of 17.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of mouse PDCD1 is approximately 40-45 kDa due to glycosylation
TypeRecombinant protein
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Conjugate/TagC-His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Radionuclide-stimulated dynamic therapy induces complementary immunogenic necroptosis and apoptosis cancer cell death pathwaysCommunications BiologyJanuary 19, 2026Christopher Egbulefu, Kvar Black, Xinming Su, Partha Karmakar, LeMoyne Habimana-Griffin, Gail Sudlow, Julie Prior, Ezugo Onejeme, Alex Zheleznyak, Baogang Xu, et al.until analysis. Quality control standards included recombinant mouse purified proteins (#50502-M08B, #50124-M08H, #50010-M03H, #53069-M08H, Sinobiological, Wayne, PA, USA; and #752602, BioLegend, San Diego, CA, USA).

(2) Arming AAV9 with a Single-Chain Fragment Variable Antibody Against PD-1 for Systemic Glioblastoma TherapyMolecular neurobiologyFebruary 1, 2025Maksoud S, Schweiger MW, Tabet EI, Xiao T, Hokayem JE, Zinter M, Carvalho LA, Breyne K, Noske DP, Chiocca EA, et al.

(3) Functional differences between rodent and human PD-1 linked to evolutionary divergence*Science ImmunologyJanuary 3, 2025Takeya Masubuchi, Lin Chen, Nimi Marcel, George A. Wen, Christine Caron, Jibin Zhang, Yunlong Zhao, Gerald P. Morris, Xu Chen, Stephen M. Hedrick, et al.from Goldbio. Recombinant protein huPD-1-His (#10377-H08H), huPD-L1-His (#10084-H08H), moPD-1-His (#50124-M08H), moPDL1-His (#50010-M08H), huICAM-1 (#10346-H08H), and moICAM-1 (#50440-M08H) were purchased from SinoBiological.

(4) A Novel Monoclonal Antibody against PD-1 for the Treatment of Viral Oncogene-Induced Tumors or Other CancerCancersSeptember 1, 2024Xu X, Yan SL, Yo YT, Chiang P, Tsai CY, Lin LL, Qin A.(Sino Biological, 11159-H08H), human CD28 (Sino Biological, 11524-HCCH), mouse PD-1 (Sino Biological, 50124-M08H), cynomolgus PD-1 (Sino Biological, 90311-C08H), human PD-1 (Sino Biological, HPLC-10377-H08H), and

(5) Dual targeting of TIGIT and PD-1 with a novel small molecule for cancer immunotherapyBiochemical pharmacologyMay 1, 2024Li Y, Li B, Wang Q, Zhang X, Zhang Q, Zhou X, Shi R, Wu Y, Zhai W, Chen Z, et al.

(6) Bispecific dendritic-T cell engager potentiates anti-tumor immunityCellJanuary 18, 2024Shapir Itai Y, Barboy O, Salomon R, Bercovich A, Xie K, Winter E, Shami T, Porat Z, Erez N, Tanay A, et al.

(7) An analgesic peptide H-20 attenuates chronic pain via the PD-1 pathway with few adverse effectsProceedings of the National Academy of Sciences of the United States of AmericaAugust 2, 2022Zhao L, Luo H, Ma Y, Zhu S, Wu Y, Lu M, Yao X, Liu X, Chen G.(mPD-L1, Fc Chimera, ab216192) was obtained from Abcam. Mouse PD-1 protein (mPD-1, ECD, His Tag, cat. no. 50124-M08H) was purchased from Sino Biological. ICR mice were acquired from the Experimental Animal Center of Nantong

(8) Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma GrowthMolecular therapy oncolyticsJune 26, 2020Bai C, Gao S, Hu S, Liu X, Li H, Dong J, Huang A, Zhu L, Zhou P, Li S, et al.(mouse CD28, Abcam, ab207143; mouse CTLA-4, Sino Biological, 50503-M08H; mouse PD1, Sino Biological, 50124-M08H; mouse TIM3, Sino Biological, 51152-M08H; mouse TIGIT, Sino Biological, 50939-M08H) and aptamers were

(9) Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitorsEMBO molecular medicineJune 8, 2020Fan Z, Tian Y, Chen Z, Liu L, Zhou Q, He J, Coleman J, Dong C, Li N, Huang J, et al.(500 ng/ml, Sino Biological, 10377‐H08H‐50) or 6×His‐tagged mPD‐1 protein (500 ng/ml, Sino Biological, 50124‐M08H‐100) was added and plates were incubated for 1 h at RT. Horseradish peroxidase (HRP)‐conjugated anti‐His

(10) Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T CellsCell reportsJuly 10, 2018Zhao Y, Harrison DL, Song Y, Ji J, Huang J, Hui E.study,N/A Strep-SNAP-B7.2EX-His10,This study,N/A Mouse MHC-I H2Kb,Enfu Hui,N/A Mouse PD-1EX-His,Sino Biological,Cat # 50124-m08h Mouse PD-L1EX-His,Sino Biological,Cat # 50010-m08h Mouse B7.2EX-His,Sino Biological,Cat # 50068-m08h Mouse

(11) Epitope mapping reveals the binding mechanism of a functional antibody cross-reactive to both human and murine programmed death 1mAbsMay 1, 2017Li D, Xu J, Wang Z, Gong Z, Liu J, Zheng Y, Li J, Li J.

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Mouse PD1 / PDCD1 Protein (ECD,His Tag)

Mouse PD1 / PDCD1 Protein (ECD,His Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (11)

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Mouse PD1 / PDCD1 Protein (ECD,His Tag) from Sino Biological, Inc.

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