Human CD47 Protein (ECD,His Tag) 12283-H08H from Sino Biological, Inc.

Product Specs
ItemHuman CD47 Protein (ECD,His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number12283-H08H
Activity1.Immobilized Human SIRP alpha hFc (Cat:11612-H02H1) at 2 µg/ml (100 µl/well) can bind Human CD47 His (Cat:12283-H08H), the EC50 of Human CD47 His is 5.0-25.0 ng/mL(QC tested). 2.Captured Anti-CD47(Research grade Ligufalimab biosimilar)(IgG4) on proA Chip can bind CD47 (Cat.No.12283-H08H) with an affinity constant of 10.82 nM as determined in a SPR assay (Biacore T200)(Routinely tested). 3.Loaded Anti-CD47(Research grade Hu5F9-G4 biosimilar)(IgG4) on ProA Biosensor, can bind human CD47 protein, His Tag (Cat.No.12283-H08H) with an affinity constant of 3.02nM as determined in BLI assay (Sartorius Octet Red384) (Routinely tested). 4.Immobilized Anti-CD47 (Research Grade Magroli*mab Biosimilar) at 2 µg/mL (100 µL/well) can bind Recombinant Human CD47 Protein (His Tag) (Cat: 12283-H08H1), the EC50 is 1.6 ng/mL(Routinely tested). 5.Immobilized Recombinant Human CD47 Protein (ECD,His Tag) (Cat: 12283-H08H) at 5 µg/mL (100 µL/well) can bind Recombinant Human SIRP gamma Protein (Fc Tag) (Cat: 11828-H02H), the EC50 is 100-300 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS,pH7.4
Size100 µg
NCBI Gene AliasesIAP, MER6, OA3
NCBI Full Gene NameCD47 molecule
Source/Expression SystemHEK293 Cells
Molecule NameCD47
SpeciesHuman
Molecular WeightThe recombinant human CD47 consists of 132 amino acids and predicts a molecular mass of 15.2 kDa. The apparent molecular mass of the protein is approximately 35-44 kDa in SDS-PAGE under reducing conditions due to glycosylation
TypeRecombinant protein
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Conjugate/TagC-His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) CAR macrophages with built-In CD47 blocker combat tumor antigen heterogeneity and activate T cells via cross-presentationNat CommunApril 30, 2025Siqi Chen, Yingyu Wang, Jessica Dang, Nuozi Song, Xiaoxin Chen, Jinhui Wang, Guo N. Huang, Christine E. Brown, Jianhua Yu, Irving L. Weissman, et al.ELISA plate was coated with 1 ug/ml of recombinant his-tag human CD47-ECD protein (SinoBiological, Cat#12283-H08H) in 100ul 1X PBS overnight. After washing and blocking with 2%BSA in PBS, wells are incubated with serial

(2) ImmunoPET Imaging of CD47 with VHH-Derived Tracers in Pancreatic CancersMolecular pharmaceuticsAugust 7, 2023Liang C, Huang W, Zhang Y, Zhang D, An S, Wu Q, Zhao H, Wang C, Huang G, Wei W, et al.

(3) Development and Characterization of Nanobody-Derived CD47 Theranostic Pairs in Solid TumorsResearch (Washington, D.C.)January 1, 2023Zhang Y, Zhang D, An S, Liu Q, Liang C, Li J, Liu P, Wu C, Huang G, Wei W, et al.nanobody derivatives A healthy alpaca was immunized with 2 mg of recombinant human CD47 protein (Cat: 12283-H08H; Sino Biological) mixed with an equal volume of Freund's complete adjuvant 6 times. Meanwhile, the extracellular

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Human CD47 Protein (ECD,His Tag)

Human CD47 Protein (ECD,His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human CD47 Protein (ECD,His Tag) from Sino Biological, Inc.

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