Human CEACAM5 / CD66e Protein (His Tag) 11077-H08H from Sino Biological, Inc.

Product Specs
ItemHuman CEACAM5 / CD66e Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number11077-H08H
Size100 µg
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
FormatLyophilized from sterile 20mM Tris, 150mM NaCl, pH 8.0
Activity1.Loaded Anti-Human CEACAM5 antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human CEACAM5 Protein, His Tag (Cat. No. 11077-H08H) with an affinity constant of 3.72 nM as determined in a BLI assay (Sartorius Octet Red384) (Routinely tested). 2.Immobilized Anti-CEA Antibody at 2 µg/mL (100 µL/well) can bind Recombinant Human CEACAM5 / CD66e Protein (His Tag)(Cat:11077-H08H),The EC50 is 5.5-16 ng/mL. 3.Anti-CEA Antibody, Human IgG1 captured on Protein A chip can bind Recombinant Human CEACAM-5/CD66e Protein, His Tag (Cat. No. 11077-H08H) with an affinity constant of 3.22 nM as determined in an SPR assay (Biacore 8K) (Routinely tested)
TypeRecombinant protein
Molecular WeightThe secreted recombinant human CEACAM5 consists of 662 amino acids and has a predicted molecular mass of 72.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of human CEACAM5 is approximately 128 and 154.7 kDa due to different glycosylation
SpeciesHuman
Molecule NameCEACAM5
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameCEA cell adhesion molecule 5
NCBI Gene AliasesCD66e, CEA

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypesCellAugust 22, 2024Yang Y, Chen X, Pan J, Ning H, Zhang Y, Bo Y, Ren X, Li J, Qin S, Wang D, et al.

(2) Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinomaFrontiers in immunologyJanuary 1, 2023Zhang C, Wang L, Zhang Q, Shen J, Huang X, Wang M, Huang Y, Chen J, Xu Y, Zhao W, et al.evaluated on days 10 and 14. We used His-tagged recombinant CEACAM5 (CEA-His; Sino Biological Inc., 11077-H08H-50) and biotin-protein L (GenScript, M00097) for specific detection of CAR expression. The following

(3) Clinically relevant dosing and pharmacokinetics of DNA-encoded antibody therapeutics in a sheep modelFrontiers in OncologyOctober 3, 2022Kevin Hollevoet, Debby Thomas, Griet Compernolle, Giles Vermeire, Elien De Smidt, Stéphanie De Vleeschauwer, Trevor R. F. Smith, Paul D. Fisher, Maarten Dewilde, Nick Geukens, et al.(limit of detection 50 ng/ml) (14). 96-well plates were coated overnight at 4°C with 2-4 µg/ml CEA (#11077-H08H, Sino Biologicals). The presence of antibodies against the in vivo expressed OVAC (i.e., anti-drug antibodies

(4) Bridging the Clinical Gap for DNA-Based Antibody Therapy Through Translational Studies in SheepHuman Gene TherapyNovember 1, 2019Kevin Hollevoet, Stéphanie De Vleeschauwer, Elien De Smidt, Giles Vermeire, Nick Geukens, Paul Declerckreported.6 Monoclonal antibody ELISA Ninety-six-well plates were coated overnight at 4C with 4 lg/mL CEA in PBS (#11077-H08H; Sino Biological) for OVAC quantification, 1 lg/mL EGFR in PBS (10001-H08H; Sino Biological) for OVAE quantification,

(5) Molecular Imaging of Radiolabeled Bispecific T-Cell Engager (89)Zr-AMG211 Targeting CEA-Positive TumorsClinical cancer research : an official journal of the American Association for Cancer ResearchOctober 15, 2018Waaijer SJH, Warnders FJ, Stienen S, Friedrich M, Sternjak A, Cheung HK, van Scheltinga AGTT, Schröder CP, de Vries EGE, Lub-de Hooge MN.89Zr-AMG211 towards CEA was tested in a competition assay with unlabeled AMG 211. Recombinant human CEACAM5 (11077-H08H; Sino Biologicals Inc.) was used as target antigen. CEACAM5 protein was diluted in 0.05 M Na2CO3 (pH

(6) Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA⁺ Metastatic Colorectal CancersMolecular therapy : the journal of the American Society of Gene TherapyMay 3, 2017Zhang C, Wang Z, Yang Z, Wang M, Li S, Li Y, Zhang R, Xiong Z, Wei Z, Shen J, et al.

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Human CEACAM5 / CD66e Protein (His Tag)

Human CEACAM5 / CD66e Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human CEACAM5 / CD66e Protein (His Tag) from Sino Biological, Inc.

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