Recombinant Human IL-1ra/IL-1F3 Protein 280-RA-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-1ra/IL-1F3 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $373.00Supplier Page View Company Product Page
Catalog Number280-RA-010
Size10 ug (also 200 ug, 50 ug)
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight17 kDa
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameIL-1ra/IL-1F3
Source/Expression SystemE. coli-derived Recombinant Human IL-1ra/IL-1F3 Protein
NCBI Full Gene Nameinterleukin 1 receptor antagonist
NCBI Gene AliasesICIL-1RA, MVCD4, IL1RA, DIRA, IL-1RN, IL1F3, IL-1ra3, IL-1ra, IRAP
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Impact of Cellular Senescence on LCN2 Expression in Salivary Gland Epithelial Cells and Oral KeratinocytesBioFactorsFebruary 18, 2026Yosuke Shikama, Kayo Yoshida, Yuka ShikamaKeratinocyte‐SFM, and then transferred to monolayers of HOK in a 12‐well plate. Recombinant human IL‐1Ra protein (#280‐RA‐010, R&D Systems, Minneapolis, MN, USA) was added just before the diluted CM was transferred to HOK. 2.6

(2) Intrinsic immunosuppressive features of monocytes suppress CAR-T19 through IL-1 pathway modulation in mantle cell lymphomaMolecular Therapy OncologyApril 19, 2025Kun Yun, R. Leo Sakemura, Ismail Can, Omar Gutierrez Gutierrez Ruiz, Ekene J. Ogbodo, Shuwen Zhang, Ateka Saleh, Truc N. Huynh, Claudia Manriquez Manriquez Roman, Olivia L. Sirpilla, et al.100 pg/mL rhIL-1β (R&D Systems, catalog no. 201-LB-010), 100 ng/mL rhIL-1ra (R&D Systems, catalog no. 280-RA-010), or 20 μg/mL IL-1ra neutralizing monoclonal antibody (clone 10309, Invitrogen, Carlsbad, CA; catalog

(3) Extending the dynamic range of biomarker quantification through molecular equalizationNature communicationsJuly 13, 2023Newman SS, Wilson BD, Mamerow D, Wollant BC, Nyein H, Rosenberg-Hasson Y, Maecker HT, Eisenstein M, Soh HT.

(4) Exploring the Pathophysiologic Cascade Leading to Osteoclastogenic Activation in Gaucher Disease Monocytes Generated via CRISPR/Cas9 TechnologyInternational journal of molecular sciencesJuly 7, 2023Ormazabal ME, Pavan E, Vaena E, Ferino D, Biasizzo J, Mucci JM, Serra F, Cifù A, Scarpa M, Rozenfeld PA, et al.

(5) Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zonebioRxiv : the preprint server for biologyMarch 6, 2023Morrison VE, Houpert MG, Trapani JB, Brockman AA, Kingsley PJ, Katdare KA, Layden HM, Nguena-Jones G, Trevisan AJ, Maguire-Zeiss KA, et al.

(6) Affinity Capture Elution (ACE) ELISA Method Development and Validation for Novel RPH-104 Drug Immunogenicity EvaluationBiomedicinesOctober 29, 2022Kolganova MA, Melnik EV, Fisher EN, Smirnov VV, Vlasov AM, Gegechkori VI, Shulga NA, Shokhin IE, Ramenskaya GV.

(7) Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behaviorJournal of neuroinflammationApril 4, 2022Cluny NL, Nyuyki KD, Almishri W, Griffin L, Lee BH, Hirota SA, Pittman QJ, Swain MG, Sharkey KA.

(8) Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer ProgressionBiomedicinesDecember 13, 2020Fan YC, Lee KD, Tsai YC.

(9) Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in miceExperimental & molecular medicineSeptember 1, 2020Namai F, Shigemori S, Ogita T, Sato T, Shimosato T.

(10) Deletion of Thioredoxin-Interacting Protein (TXNIP) Abrogates High Fat Diet-induced Retinal Leukostasis, Barrier Dysfunction and Microvascular Degeneration in a Mouse Obesity ModelInternational journal of molecular sciencesJune 1, 2020Mohamed IN, Sheibani N, El-Remessy AB.

(11) Glycolytic reprogramming of macrophages activated by NOD1 and TLR4 agonists: No association with proinflammatory cytokine production in normoxiaThe Journal of biological chemistryMarch 6, 2020Murugina NE, Budikhina AS, Dagil YA, Maximchik PV, Balyasova LS, Murugin VV, Melnikov MV, Sharova VS, Nikolaeva AM, Chkadua GZ, et al.

(12) Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagyOncology reportsMarch 1, 2020Chen Y, Yang Z, Deng B, Wu D, Quan Y, Min Z.

(13) Mycobacterium tuberculosis Lipoarabinomannan Activates Human Neutrophils via a TLR2/1 Mechanism Distinct from Pam₃CSK₄Journal of immunology (Baltimore, Md. : 1950)February 1, 2020Hook JS, Cao M, Weng K, Kinnare N, Moreland JG.

(14) Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independencePloS oneJanuary 1, 2020Dahl HC, Kanchwala M, Thomas-Jardin SE, Sandhu A, Kanumuri P, Nawas AF, Xing C, Lin C, Frigo DE, Delk NA.

(15) IL-1RA is part of the inflammasome-regulated immune response in bladder epithelial cells and influences colonization of uropathogenic E. coliCytokineNovember 1, 2019Lindblad A, Persson K, Demirel I.

(16) Transition from metal-DTH resistance to susceptibility is facilitated by NLRP3 inflammasome signaling induced Th17 reactivity: Implications for orthopedic implantsPloS oneJanuary 1, 2019Samelko L, Caicedo MS, Jacobs J, Hallab NJ.

(17) Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activationMolecular visionJanuary 1, 2019Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M.

(18) Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)Journal of cell communication and signalingSeptember 1, 2017Kinnunen K, Piippo N, Loukovaara S, Hytti M, Kaarniranta K, Kauppinen A.

(19) Advanced glycation end products regulate anabolic and catabolic activities via NLRP3-inflammasome activation in human nucleus pulposus cellsJournal of cellular and molecular medicineJuly 1, 2017Song Y, Wang Y, Zhang Y, Geng W, Liu W, Gao Y, Li S, Wang K, Wu X, Kang L, et al.

(20) Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size SpecificFrontiers in immunologyJanuary 1, 2017Nishijima N, Hirai T, Misato K, Aoyama M, Kuroda E, Ishii KJ, Higashisaka K, Yoshioka Y, Tsutsumi Y.

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Recombinant Human IL-1ra/IL-1F3 Protein

IL-1ra/IL-1F3 Protein

IL-1ra/IL-1F3 Protein

IL-1ra/IL-1F3 Protein

IL-1ra/IL-1F3 Protein

Recombinant Human IL-1ra/IL-1F3 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-1ra/IL-1F3 Protein from R&D Systems, a Bio-Techne Brand

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