Recombinant Human IL-1 alpha/IL-1F1 Protein, CF 200-LA-002/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-1 alpha/IL-1F1 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $211.00Supplier Page View Company Product Page
Catalog Number200-LA-002/CF
SpeciesHuman
Size2 ug (also 10 ug)
FormatSupplied as a 0.2 µm filtered solution in PBS
Molecule NameIL-1 alpha/IL-1F1
Source/Expression SystemE. coli-derived Recombinant Human IL-1 alpha/IL-1F1 Protein, CF
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight18 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening
NCBI Full Gene Nameinterleukin 1 alpha
NCBI Gene AliasesIL-1 alpha, IL-1A, IL1, IL1-ALPHA, IL1F1

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-38 is a negative regulator of trained immunity—A retrospective multi-omics studyiScienceNovember 21, 2025Lisa U. Teufel, Vasiliki Matzaraki, Lukas Folkman, Dennis M. de Graaf, Rob ter Horst, Simone J.C.F.M. Moorlag, Jéssica C. dos Santos, Catharina M. Mulders-Manders, Thomas Krausgruber, Charles Dinarello, et al.Denver, Colorado, USA",N/A IL-1Ra (Anakinra),MedChemExpress,Cat# 143090-92-0 IL-1α,R&D Systems,Cat# 200-LA-002/CF "β-glucan (β 1,3-(D)-glucan","Professor David Williams, College of Medicine, Johnson City, USA",N/A Lipopolysaccharide,Sigma-Aldrich,Cat#L2880;

(2) ARP2/3 complex affects myofibroblast differentiation and migration in pancreatic ductal adenocarcinomaInternational Journal of CancerMarch 15, 2025Yifeng Sun, Yina Qiao, Yiqi Niu, Bindhu Kollivayal Madhavan, Chao Fang, Jingxiong Hu, Kathleen Schuck, Benno Traub, Helmut Friess, Ingrid Herr, et al.(#SML00006, Sigma‐Aldrich, Munich, Germany), human TGFβ1 (#T7039‐2UG, Sigma‐Aldrich), and human IL1α (#200‐LA‐002/CF, R&D Systems, Minneapolis, USA). Human immortalized PSCs were cultured in a 6‐well plate using complete

(3) Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironmentNature communicationsJuly 31, 2023Xue M, Zhu Y, Jiang Y, Han L, Shi M, Su R, Wang L, Xiong C, Wang C, Wang T, et al.were incubated with Panc-1 cells with for 24–48 h. About 1 ng/ml recombined human IL-1α (R&D systems, 200-LA-002/CF) were incubated with CAFs for 24 h for in vitro assays or 10 ng/ml for 72 h for in vivo assay. For protein

(4) Human Primary Astrocytes Differently Respond to Pro- and Anti-Inflammatory StimuliBiomedicinesJuly 22, 2022Szpakowski P, Ksiazek-Winiarek D, Turniak-Kusy M, Pacan I, Glabinski A.

(5) Inflammasome Activation in Retinal Pigment Epithelium from Human Donors with Age-Related Macular DegenerationCellsJune 30, 2022Ebeling MC, Fisher CR, Kapphahn RJ, Stahl MR, Shen S, Qu J, Montezuma SR, Ferrington DA.

(6) Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial CellsInternational journal of molecular sciencesApril 20, 2022Filidou E, Kandilogiannakis L, Tarapatzi G, Spathakis M, Steiropoulos P, Mikroulis D, Arvanitidis K, Paspaliaris V, Kolios G.

(7) Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humansEBioMedicineMarch 1, 2022Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, et al.

(8) The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized PatientsMolecular and cellular biologyJanuary 20, 2022McAleavy M, Zhang Q, Ehmann PJ, Xu J, Wipperman MF, Ajithdoss D, Pan L, Wakai M, Simonson R, Gadi A, et al.

(9) ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast PhenotypeInternational journal of molecular sciencesOctober 19, 2021Sheldon H, Alexander J, Bridges E, Moreira L, Reilly S, Ang KH, Wang D, Lin S, Haider S, Banham AH, et al.

(10) Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosisNature communicationsJuly 27, 2021Biavasco R, Lettera E, Giannetti K, Gilioli D, Beretta S, Conti A, Scala S, Cesana D, Gallina P, Norelli M, et al.

(11) Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 CellsCellsJune 6, 2021Bhattarai N, Korhonen E, Mysore Y, Kaarniranta K, Kauppinen A.

(12) Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilitiesCell reportsMay 18, 2021Hayn M, Hirschenberger M, Koepke L, Nchioua R, Straub JH, Klute S, Hunszinger V, Zech F, Prelli Bozzo C, Aftab W, et al.

(13) TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial CellsInternational journal of molecular sciencesMay 5, 2021Ranta-Aho S, Piippo N, Korhonen E, Kaarniranta K, Hytti M, Kauppinen A.

(14) Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic InflammationCellsMarch 2, 2021Bernau K, Leet JP, Floerke H, Bruhn EM, Noll AL, McDermott IS, Esnault S, Jarjour NN, Sandbo N.

(15) Soluble Compounds Released by Hypoxic Stroma Confer Invasive Properties to Pancreatic Ductal AdenocarcinomaBiomedicinesOctober 22, 2020Liu D, Steins A, Klaassen R, van der Zalm AP, Bennink RJ, van Tienhoven G, Besselink MG, Bijlsma MF, van Laarhoven HWM.

(16) The Pseudomonas aeruginosa protease LasB directly activates IL-1βEBioMedicineOctober 1, 2020Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN.

(17) Systemic conditioned medium treatment from interleukin-1 primed mesenchymal stem cells promotes recovery after strokeStem cell research & therapyJanuary 21, 2020Cunningham CJ, Wong R, Barrington J, Tamburrano S, Pinteaux E, Allan SM.

(18) PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitisThe Journal of biological chemistryJanuary 17, 2020Powers NE, Swartzwelter B, Marchetti C, de Graaf DM, Lerchner A, Schlapschy M, Datar R, Binder U, Edwards CK 3rd, Skerra A, et al.

(19) ¹⁸F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse ModelOncoTargets and therapyJanuary 1, 2020Li X, Yin G, Ji W, Liu J, Zhang Y, Wang J, Zhu X, Zhu L, Dai D, Ma W, et al.

(20) Targeting TGFβR2-mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancerEMBO molecular medicineNovember 7, 2019Huang H, Zhang Y, Gallegos V, Sorrelle N, Zaid MM, Toombs J, Du W, Wright S, Hagopian M, Wang Z, et al.and recombinant mouse IL‐6 (575704) were obtained from BioLegend. Mouse (400‐ML‐005/CF) and human (200‐LA‐002/CF) IL‐1α, mouse IL‐6 (DY406), mouse LIF (DY449), and human IL‐6 (DY206) DuoSet ELISA kits were obtained

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IL-1 alpha/IL-1F1 Protein

IL-1 alpha/IL-1F1 Protein

IL-1 alpha/IL-1F1 Protein

IL-1 alpha/IL-1F1 Protein

IL-1 alpha/IL-1F1 Protein

Recombinant Human IL-1 alpha/IL-1F1 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-1 alpha/IL-1F1 Protein, CF from R&D Systems, a Bio-Techne Brand

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