LIGHT/TNFSF14 Protein 664-LI-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemLIGHT/TNFSF14 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $423.00Supplier Page View Company Product Page
Catalog Number664-LI-025
SpeciesHuman
Molecule NameLIGHT/TNFSF14
Size25 ug
NCBI Full Gene NameTNF superfamily member 14
NCBI Gene AliasesHVEML, CD258, LTg, LIGHT
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Source/Expression SystemNS0-derived Recombinant Human LIGHT/TNFSF14 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Conjugate/TagUnconjugated

Specifications/Features

Available conjugates: Sizes Available: 25 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Tumor Necrosis Factor Superfamily 14 Regulates the Inflammatory Response of Human Dental Pulp Stem CellsCurrent issues in molecular biologyDecember 11, 2024Alrshedan A, Elsafadi M, Muthurangan M, Al-Hadlaq S.Dental Pulp Stem Cells Recombinant human TNFSF14 (R&D Systems Minneapolis, MN, USA, catalog number 664-LI-025) was dissolved in 0.1% bovine serum albumin (BSA)-phosphate-buffered saline (PBS) and stored at −20

(2) Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancerEBioMedicineMarch 1, 2024Di Modugno F, Di Carlo A, Spada S, Palermo B, D'Ambrosio L, D'Andrea D, Morello G, Belmonte B, Sperduti I, Balzano V, et al.

(3) PI16(+) reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial nichesNature immunologyJuly 1, 2023De Martin A, Stanossek Y, Lütge M, Cadosch N, Onder L, Cheng HW, Brandstadter JD, Maillard I, Stoeckli SJ, Pikor NB, et al.

(4) LIGHT (TNFSF14) promotes the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cellsPloS oneJanuary 1, 2023Heo SK, Yu HM, Kim DK, Seo HJ, Shin Y, Kim SA, Kim M, Kim Y, Lee YJ, Noh EK, et al.

(5) LIGHT (TNFSF14) enhances osteogenesis of human bone marrow-derived mesenchymal stem cellsPloS oneJanuary 1, 2021Heo SK, Choi Y, Jeong YK, Ju LJ, Yu HM, Kim DK, Seo HJ, Lee YJ, Cheon J, Koh S, et al.

(6) Redesigning HVEM Interface for Selective Binding to LIGHT, BTLA, and CD160Structure (London, England : 1993)November 3, 2020Shrestha R, Garrett-Thomson SC, Liu W, Almo SC, Fiser A.6177-CD-050 Human BTLA-His,R&D Systems,Cat# 9235-BT-050 Human LIGHT (TNF14) His,R&D Systems,Cat# 664-LI-025 Deposited Data,Deposited Data,Deposited Data Human HVEM and BTLA complex,"(Compaan, et al., 2005)",PDB:

(7) Complement-activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cellsThe Journal of clinical investigationJuly 1, 2020Xie CB, Jiang B, Qin L, Tellides G, Kirkiles-Smith NC, Jane-Wit D, Pober JS.complement (MilliporeSigma, S1764) for 4 hours. HUVECs were treated with 100 ng/mL LIGHT (R&D Systems, 664LI-025) for 18 hours, 100 pg/mL recombinant IL-1β (Thermo Fisher Scientific, 10139HNAE5) for 6 hours, and 10

(8) The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB-Inducing KinaseMolecules and cellsJanuary 31, 2020Jang H, Park S, Kim J, Kim JH, Kim SY, Cho S, Park SG, Park BC, Kim S, Kim JH.

(9) Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategiesThe ocular surfaceJuly 1, 2019An S, Raju I, Surenkhuu B, Kwon JE, Gulati S, Karaman M, Pradeep A, Sinha S, Mun C, Jain S.

(10) Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel DiseaseCellOctober 4, 2018Kinchen J, Chen HH, Parikh K, Antanaviciute A, Jagielowicz M, Fawkner-Corbett D, Ashley N, Cubitt L, Mellado-Gomez E, Attar M, et al.Recombinant Human EGF,PeproTech,Cat#AF-100 Recombinant Human IL-6,R&D Systems,Cat#206-IL-010 Recombinant Human LIGHT/TNFSF14,R&D Systems,Cat#664-LI-025 A 83-01,R&D Systems,Cat#2939/10 [LEU15]-Gastrin I HUMAN,Sigma Aldrich,Cat#G9145 Prostaglandin E2,Sigma Aldrich

(11) TNFSF14 inhibits melanogenesis via NF-kB signaling in melanocytesCytokineOctober 1, 2018Kim KH, Choi H, Kim HJ, Lee TR.

(12) An anti-TL1A antibody for the treatment of asthma and inflammatory bowel diseasemAbsMay 1, 2018Clarke AW, Poulton L, Shim D, Mabon D, Butt D, Pollard M, Pande V, Husten J, Lyons J, Tian C, et al.

(13) Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHTJournal of molecular endocrinologyApril 1, 2018Abadpour S, Halvorsen B, Sahraoui A, Korsgren O, Aukrust P, Scholz H.

(14) TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-βFrontiers in immunologyJanuary 1, 2018da Silva Antunes R, Mehta AK, Madge L, Tocker J, Croft M.

(15) LIGHT is increased in patients with coronary disease and regulates inflammatory response and lipid metabolism in oxLDL-induced THP-1 macrophagesBiochemical and biophysical research communicationsAugust 26, 2017Yuan X, Gu Y, Lai X, Gu Q.

(16) A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in miceNature communicationsDecember 16, 2016Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, et al.

(17) LIGHT (TNFSF14) Increases the Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem CellsPloS oneJanuary 1, 2016Heo SK, Noh EK, Gwon GD, Kim JY, Jo JC, Choi Y, Koh S, Baek JH, Min YJ, Kim H.

(18) The TNF Family Molecules LIGHT and Lymphotoxin αβ Induce a Distinct Steroid-Resistant Inflammatory Phenotype in Human Lung Epithelial CellsJournal of immunology (Baltimore, Md. : 1950)September 1, 2015da Silva Antunes R, Madge L, Soroosh P, Tocker J, Croft M.

(19) The Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin FibrosisThe Journal of investigative dermatologyAugust 1, 2015Herro R, Antunes RDS, Aguilera AR, Tamada K, Croft M.

(20) Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cellsPloS oneJanuary 1, 2014Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y.

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Recombinant Human LIGHT/TNFSF14 Protein

LIGHT/TNFSF14 Protein

LIGHT/TNFSF14 Protein

LIGHT/TNFSF14 Protein

LIGHT/TNFSF14 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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LIGHT/TNFSF14 Protein from R&D Systems, a Bio-Techne Brand

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