Angiopoietin-2 Protein 623-AN-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemAngiopoietin-2 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $381.00Supplier Page View Company Product Page
Catalog Number623-AN-025
SpeciesHuman
Molecule NameAngiopoietin-2
Size25 ug
NCBI Full Gene Nameangiopoietin 2
NCBI Gene AliasesLMPHM10, ANG2, AGPT2
FormatLyophilized from a 0.2 µm filtered solution in MOPS, NaCl, CHAPS and PEG with BSA as a carrier protein and Trehalose
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Source/Expression SystemNS0-derived Recombinant Human Angiopoietin-2 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Conjugate/TagUnconjugated

Specifications/Features

Available conjugates: Sizes Available: 25 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A Study on the Levels of Selected Proangiogenic Proteins in Human Tissues and Plasma in Relation to Brain GliomaInternational journal of molecular sciencesMay 16, 2025Zielinska Z, Giełażyn J, Dzieciol-Anikiej Z, Dzieciol J, Mrozek P, Reszec-Gielazyn J, Gorodkiewicz E.

(2) miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and DifferentiationCellsJanuary 8, 2025Sanchez V, Harel S, Sa'ub AK, Mayaki D, Hussain SNA.

(3) Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitorJournal of translational medicineOctober 14, 2024Keller S, Kunz U, Schmid U, Beusmans J, Büchert M, He M, Jayadeva G, Le Tourneau C, Luedtke D, Niessen HG, et al.detection antibody. As reference standard, bulk material of one lot was banked in aliquots at − 70 °C (623-AN-025, R&D Systems/BioTechne Inc. USA). The assay was calibrated relative to this recombinant standard material.

(4) BMP2 Diminishes Angiotensin II-Induced Atrial Fibrillation by Inhibiting NLRP3 Inflammasome Signaling in Atrial FibroblastsBiomoleculesAugust 25, 2024Yuan Y, Zhang H, Xia E, Zhao X, Gao Q, Mu H, Liu X, Tian Y, Liu L, Shen Q, et al.

(5) Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived SpheroidsBiomedicinesDecember 30, 2023Romanzi A, Milosa F, Marcelli G, Critelli RM, Lasagni S, Gigante I, Dituri F, Schepis F, Cadamuro M, Giannelli G, et al.

(6) An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zoneExperimental & molecular medicineFebruary 1, 2023Lee E, Lee EA, Kong E, Chon H, Llaiqui-Condori M, Park CH, Park BY, Kang NR, Yoo JS, Lee HS, et al.

(7) TIE2-high cervical cancer cells promote tumor angiogenesis by upregulating TIE2 and VEGFR2 in endothelial cellsTranslational oncologyDecember 1, 2022Tan S, Chen Y, Du S, Li W, Liu P, Zhao J, Yang P, Cai J, Gao R, Wang Z.

(8) Gastric Cancer-Derived Extracellular Vesicles (EVs) Promote Angiogenesis via Angiopoietin-2CancersJune 15, 2022Kalfon T, Loewenstein S, Gerstenhaber F, Leibou S, Geller H, Sher O, Nizri E, Lahat G.

(9) Angpt2/Tie2 autostimulatory loop controls tumorigenesisEMBO molecular medicineMay 9, 2022Karabid NM, Wiedemann T, Gulde S, Mohr H, Segaran RC, Geppert J, Rohm M, Vitale G, Gaudenzi G, Dicitore A, et al.applications. The Tie2 kinase inhibitor was purchased by Abcam (ab141270) and dissolved in DMSO. rhANGPT2 (623‐AN‐025) was from R&D Systems. Lentiviral vectors for the knockdown of Ang‐2 purchased from Sigma‐Aldrich (MISSION®

(10) Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse modelNature communicationsJanuary 25, 2021Zhou HJ, Qin L, Jiang Q, Murray KN, Zhang H, Li B, Lin Q, Graham M, Liu X, Grutzendler J, et al.

(11) Angiopoietin-2 Promotes Inflammatory Activation in Monocytes of Systemic Sclerosis PatientsInternational journal of molecular sciencesDecember 15, 2020Carvalheiro T, Lopes AP, van der Kroef M, Malvar-Fernandez B, Rafael-Vidal C, Hinrichs AC, Servaas NH, Bonte-Mineur F, Kok MR, Beretta L, et al.

(12) Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro AngiogenesisCellsJuly 2, 2020Harel S, Sanchez-Gonzalez V, Echavarria R, Mayaki D, Hussain SN.

(13) Influence of Stress and Depression on the Immune System in Patients Evaluated in an Anti-aging UnitFrontiers in psychologyJanuary 1, 2020Cañas-González B, Fernández-Nistal A, Ramírez JM, Martínez-Fernández V.

(14) Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor OutflowInvestigative ophthalmology & visual scienceOctober 1, 2019Thackaberry EA, Zhou Y, Zuch de Zafra CL, Fuh G, Lee CV, Sanowar S, Ridgway JB, Kusi AM, Farman C, Booler H, et al.

(15) Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degenerationScience advancesFebruary 1, 2019Kim J, Park JR, Choi J, Park I, Hwang Y, Bae H, Kim Y, Choi W, Yang JM, Han S, et al.

(16) Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retinaeLifeNovember 16, 2018Elamaa H, Kihlström M, Kapiainen E, Kaakinen M, Miinalainen I, Ragauskas S, Cerrada-Gimenez M, Mering S, Nätynki M, Eklund L.protein",COMP-ANGPT1,Other,,"A gift from Prof. Gou Young Koh, KAIST" "Peptide, recombinant protein",ANGPT2,R & D Systems,623-AN-025, "Peptide, recombinant protein",Angpt4,R & D Systems,738-AN-025, "Peptide, recombinant protein",ANGPT4,R & D Systems

(17) Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosisBritish journal of pharmacologyJuly 1, 2018Wang M, Chen DQ, Chen L, Cao G, Zhao H, Liu D, Vaziri ND, Guo Y, Zhao YY.

(18) Angiopoietin-2 promotes extracellular matrix degradation in human degenerative nucleus pulposus cellsInternational journal of molecular medicineJune 1, 2018Wang K, Kang L, Liu W, Song Y, Wu X, Zhang Y, Hua W, Zhao K, Li S, Tu J, et al.

(19) Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic ActivitiesJournal of immunology (Baltimore, Md. : 1950)June 1, 2018Lavoie SS, Dumas E, Vulesevic B, Neagoe PE, White M, Sirois MG.

(20) IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastomaOncotargetMarch 20, 2018Conroy S, Kruyt FAE, Wagemakers M, Bhat KPL, den Dunnen WFA.

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Angiopoietin-2 Protein

Angiopoietin-2 Protein

Angiopoietin-2 Protein

Angiopoietin-2 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (54)

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Angiopoietin-2 Protein from R&D Systems, a Bio-Techne Brand

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