Recombinant Human Frizzled-4 Protein, CF 5847-FZ-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Frizzled-4 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number5847-FZ-050
FormatLyophilized from a 0.2 µm filtered solution in PBS
SpeciesHuman
Molecule NameFrizzled-4
Size50 ug
NCBI Full Gene Namefrizzled class receptor 4
NCBI Gene AliasesFzE4, CD344, FEVR, Fz4, hFz4, GPCR, FZD4S, Fz-4, EVR1
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 58-60 kDa, reducing conditions
Theoretical: 42.8 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Frizzled-4 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) Development of Norrin-Based Protein Therapeutic for Activation of Norrin-Wnt Signaling in Human Retinal Endothelial CellsInternational Journal of Molecular SciencesNovember 24, 2025Kenneth P. Mitton, Wendy A. Dailey, Steven Q. Krikor, Kimberly A. Drenserreceptor, Frizzled-4 (FZD4). Briefly, a rhFrizzled-4/FC Chimera (R&D Systems, Minneapolis, MN, USA; 5847-FZ-050) was coated onto the surface of a 96-well plate overnight. The next day, the plate was washed with buffered

(2) A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathyEMBO molecular medicineJuly 7, 2021Chidiac R, Abedin M, Macleod G, Yang A, Thibeault PE, Blazer LL, Adams JJ, Zhang L, Roehrich H, Jo HN, et al.

(3) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

Recombinant Human Frizzled-4 Protein, CF from R&D Systems, a Bio-Techne Brand