Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF 862-VC-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human VCAM-1/CD106 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $434.00Supplier Page View Company Product Page
Catalog Number862-VC-100
Size100 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 115-130 kDa, reducing conditions
Theoretical: 101.6 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameVCAM-1/CD106
Source/Expression SystemNS0-derived Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF
NCBI Full Gene Namevascular cell adhesion molecule 1
NCBI Gene AliasesINCAM-100, CD106
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 week, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Matrix Tropism Influences Endometriotic Cell Attachment PatternsAdvanced Functional MaterialsDecember 1, 2025Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley,R&D Systems,4519-GP-050,0.5 mg/mL Ovary,Versican [81],R&D Systems,3054-VN-050,0.5 mg/mL Ovary,VCAM-1 [82],R&D Systems,862-VC-100,1 mg/mL Ovary,ICAM-1 [83],R&D Systems,ADP4–050,1 mg/mL Ovary,EP-CAM [84],R&D Systems,960-EP-050,1

(2) Centrosomal actin pool levels regulated by localized PKA set the threshold for T cell polarizationEMBO ReportsAugust 26, 2025Morgane Simao, Fabienne Régnier, Clotilde RandriamampitaSDF1-α) was purchased from Peprotech (300-28 A) and VCAM-1 (CD106 Fc chimera protein) from R&D Systems (862-VC-100). Calcium measurements were performed with Fura-2/AM (Molecular Probes, F1225). For calcium chelation,

(3) A CD25-CCR7 complex initiates non-canonical IL-2 signalingbioRxiv : the preprint server for biologyFebruary 4, 2025Kim SHJ, Lee H, Gingras A, Ley K, Spangler JB, Ginsberg MH.

(4) Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLPCell Stem CellJanuary 2, 2025Ran Jing, Marcelo Falchetti, Tianxiao Han, Mohamad Najia, Luca T. Hensch, Eleanor Meader, Edroaldo Lummertz Lummertz da Rocha, Martin Kononov, Stephanie Wang, Trevor Bingham, et al.Technologies,Cat#09500 Gentle cell dissociation reagent,STEMCELL Technologies,Cat#100-0485 rhVCAM-1,R&D Systems,Cat#862-VC-100 Epigenetics screening library,Cayman Chemical,Cat#11076 UNC0224,Tocris,Cat#3861 SB431542,STEMCELL Technologies

(5) Inhibition of Mac-1 allows human macrophages to migrate against the direction of shear flow on ICAM-1Molecular Biology of the CellOctober 1, 2024Aman Mittal, Subham Guin, Ai Mochida, Daniel A. Hammer, Alexander BuffoneProtein A/G (ab52213) was purchased from BioVision Inc. Recombinant human ICAM-1 Fc (720-1C) and VCAM-1 Fc (862-VC-100) were purchased from R&D Systems. Duralastic sheeting was purchased from Allied Biomedical. Human Type

(6) Inhibition of Mac-1 allows human macrophages to migrate against the direction of shear flow on ICAM-1Mol Biol CellSeptember 20, 2024Aman Mittal, Subham Guin, Ai Mochida, Daniel A. Hammer, Alexander BuffoneProtein A/G (ab52213) was purchased from BioVision Inc. Recombinant human ICAM-1 Fc (720-1C) and VCAM-1 Fc (862-VC-100) were purchased from R&D Systems. Duralastic sheeting was purchased from Allied Biomedical. Human Type

(7) The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1bioRxiv : the preprint server for biologyDecember 22, 2023Ullo MF, D'Amico AE, Lavenus SB, Logue JS.

(8) The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1Research squareNovember 2, 2023Ullo MF, D'Amico AE, Lavenus SB, Logue JS.

(9) Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatmentNature communicationsJuly 20, 2023Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, et al.recombinant ICAM-1 (#720-IC-200, R&D Systems, Wiesbaden, Germany, and generated in-house) or VCAM-1 (#862-VC-100, R&D Systems, Wiesbaden, Germany) or MAdCAM-1 (#6056-MC-050, R&D Systems) Fc-fusion protein in PBS.

(10) Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and ReperfusionInternational journal of molecular sciencesJuly 7, 2023Wilkins GC, Gilmour J, Giannoudaki E, Kirby JA, Sheerin NS, Ali S.

(11) Membrane phase separation drives responsive assembly of receptor signaling domainsNature chemical biologyJune 1, 2023Shelby SA, Castello-Serrano I, Wisser KC, Levental I, Veatch SL.for 1 hour at room temperature with recombinant VCAM-1/human Fc chimeric protein (R&D Systems, Cat# 862-VC-100) at 10 μg/mL, and rinsed thoroughly before use. Goat anti-mouse IgM(μ) Fab fragments were obtained from

(12) An isoform of the giant protein titin is a master regulator of human T lymphocyte traffickingCell reportsMay 30, 2023Toffali L, D'Ulivo B, Giagulli C, Montresor A, Zenaro E, Delledonne M, Rossato M, Iadarola B, Sbarbati A, Bernardi P, et al.

(13) EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activityCell stem cellAugust 4, 2022Jing R, Scarfo I, Najia MA, Lummertz da Rocha E, Han A, Sanborn M, Bingham T, Kubaczka C, Jha DK, Falchetti M, et al.Technologies,Cat#09500 Gentle cell dissociation reagent,STEMCELL Technologies,Cat#100-0485 rhVCAM-1,R&D Systems,Cat#862-VC-100 SB431542,STEMCELL Technologies,Cat#72234 CHIR99021,STEMCELL Technologies,Cat#72054 bFGF,Gemini,Cat#300-112p VEGF,R&D Systems

(14) The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migrationScience advancesApril 15, 2022Mastrogiovanni M, Vargas P, Rose T, Cuche C, Esposito E, Juzans M, Laude H, Schneider A, Bernard M, Goyard S, et al.

(15) PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammationNature communicationsApril 1, 2022Schmid MC, Kang SW, Chen H, Paradise M, Ghebremedhin A, Kaneda MM, Chin SM, Do A, Watterson DM, Varner JA.IL-6, TNFα, VEGF-A, or medium together with 1 mg/ml mouse VCAM-1/human-Fc fusion protein (R&D Systems #862-VC-100). Cells were washed twice and incubated with donkey anti-human-Fc antibody (Jackson Immunoresearch)

(16) Liver sinusoidal endothelial cell expressed vascular cell adhesion molecule 1 promotes liver fibrosisFrontiers in immunologyJanuary 1, 2022Guo Q, Furuta K, Islam S, Caporarello N, Kostallari E, Dielis K, Tschumperlin DJ, Hirsova P, Ibrahim SH.

(17) cAMP Bursts Control T Cell Directionality by Actomyosin Cytoskeleton RemodelingFrontiers in Cell and Developmental BiologyMay 20, 2021Morgane Simao et al.SDF1-α) was purchased from Peprotech (300-28A) and VCAM-1 (CD106 Fc chimera protein) from R&D Systems (862-VC-100). Calcium measurements were performed with Fura-2/AM (Molecular Probes, F1225). DMACM-caged 8-Br-cAMP

(18) Monocyte phenotyping and management of lipoprotein X syndromeJournal of clinical lipidologyNovember 1, 2020Lian Z, Saeed A, Peng X, Perrard XD, Jia X, Hussain A, Ballantyne CM, Wu H.

(19) Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse modelHaematologicaJanuary 1, 2020Natoni A, Farrell ML, Harris S, Falank C, Kirkham-McCarthy L, Macauley MS, Reagan MR, O'Dwyer M.

(20) Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cellsThe Journal of clinical investigationMay 14, 2019Karpova D, Rettig MP, Ritchey J, Cancilla D, Christ S, Gehrs L, Chendamarai E, Evbuomwan MO, Holt M, Zhang J, et al.

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Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF

Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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