Recombinant Human IL-5 Protein, CF 205-IL-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-5 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $223.00Supplier Page View Company Product Page
Catalog Number205-IL-005/CF
SpeciesHuman
Molecule NameIL-5
Source/Expression SystemSf 21 (stably transfected)-derived Recombinant Human IL-5 Protein, CF
FormatSupplied as a 0.2 µm filtered solution in PBS
Size5 ug (also 25 ug)
NCBI Full Gene Nameinterleukin 5
NCBI Gene AliasesIL-5, EDF, TRF
Molecular WeightObserved: 11-16 kDa, reducing conditions
Theoretical: 13.1 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -20 to -70 °C under sterile conditions after opening
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Linking adipose tissue eosinophils, IL-4, and leptin in human obesity and insulin resistanceJCI insightFebruary 8, 2024Hernandez JD, Li T, Ghannam H, Rau CM, Masuda MY, Madura JA 2nd, Jacobsen EA, De Filippis E.21985023), antibiotic antimycotic solution (Sigma-Aldrich, A5955-100ML), 1 ng/mL of human IL-5 (R&D Systems, 205-IL-005/CF), 5 ng/mL of human GM-CSF (R&D Systems, 215-GM-010/CF), and 50 ng/mL of human IL-33 (R&D Systems, 3625-IL-010/CF)

(2) Localization and RNA Interference-Driven Inhibition of a Brugia malayi-Encoded Interleukin-5 Receptor Binding ProteinInfection and immunityMay 19, 2022Mejia R, Bennuru S, Oksov Y, Lustigman S, Munirathinam G, Kalyanasundaram R, Nutman TB.

(3) Enhanced 15-Lipoxygenase 1 Production is Related to Periostin Expression and Eosinophil Recruitment in Eosinophilic Chronic RhinosinusitisBiomoleculesNovember 18, 2020Imoto Y, Takabayashi T, Sakashita M, Kato Y, Yoshida K, Kidoguchi M, Koyama K, Adachi N, Kimura Y, Ogi K, et al.

(4) T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal InflammationCell reportsJune 30, 2020Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C.

(5) Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separationBMC research notesApril 10, 2020Cao Y, Shin S, Carroll DJ, O'Sullivan JA, Bochner BS.

(6) Fibrinogen Is a Specific Trigger for Cytolytic Eosinophil DegranulationJournal of immunology (Baltimore, Md. : 1950)January 15, 2020Coden ME, Loffredo LF, Walker MT, Jeong BM, Nam K, Bochner BS, Abdala-Valencia H, Berdnikovs S.

(7) The role of IL-36γ and its regulation in eosinophilic inflammation in allergic rhinitisCytokineMay 1, 2019Qin X, Liu M, Zhang S, Wang C, Zhang T.

(8) Interleukin-5 suppresses Vascular Endothelial Growth Factor-induced angiogenesis through STAT5 signalingCytokineOctober 1, 2018Bucher F, Lee J, Shin S, Kim MS, Oh YS, Ha S, Zhang H, Yea K.

(9) Myeloid-derived growth factor is a resident endoplasmic reticulum proteinThe Journal of biological chemistryAugust 24, 2018Bortnov V, Annis DS, Fogerty FJ, Barretto KT, Turton KB, Mosher DF.

(10) IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophilsCell death & diseaseMay 1, 2018Zellweger F, Buschor P, Hobi G, Brigger D, Dahinden CA, Villiger PM, Eggel A.

(11) Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostinPloS oneJanuary 1, 2018Barretto KT, Swanson CM, Nguyen CL, Annis DS, Esnault SJ, Mosher DF, Johansson MW.

(12) IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migrationClinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyOctober 1, 2017Johansson MW, Khanna M, Bortnov V, Annis DS, Nguyen CL, Mosher DF.

(13) Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of AllergenJournal of immunology (Baltimore, Md. : 1950)August 1, 2017Schroeder JT, Bieneman AP.

(14) Human eosinophils constitutively express a unique serine protease, PRSS33Allergology international : official journal of the Japanese Society of AllergologyJuly 1, 2017Toyama S, Okada N, Matsuda A, Morita H, Saito H, Fujisawa T, Nakae S, Karasuyama H, Matsumoto K.

(15) Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytesImmunologyJanuary 1, 2017Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota SI, Ota Y, Mitoma H, Akahoshi M, Mori Y, Iwasaki H, et al.

(16) The effect of hepatocyte growth factor on secretory functions in human eosinophilsCytokineDecember 1, 2016Yamauchi Y, Ueki S, Konno Y, Ito W, Takeda M, Nakamura Y, Nishikawa J, Moritoki Y, Omokawa A, Saga T, et al.

(17) Impaired P2X1 Receptor-Mediated Adhesion in Eosinophils from Asthmatic PatientsJournal of immunology (Baltimore, Md. : 1950)June 15, 2016Wright A, Mahaut-Smith M, Symon F, Sylvius N, Ran S, Bafadhel M, Muessel M, Bradding P, Wardlaw A, Vial C.

(18) CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptorsmAbsJanuary 1, 2016Panousis C, Dhagat U, Edwards KM, Rayzman V, Hardy MP, Braley H, Gauvreau GM, Hercus TR, Smith S, Sehmi R, et al.expressed and purified from E.coli.68 Carrier-free recombinant human IL-5 was purchased from R&D Systems (205-IL-005/CF). Cytokines (IL-3, GM-CSF) for cellular assays were purchased from R&D Systems (203-IL-010, 215-GM-010).

(19) Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB-induced Bcl-xL for inhibition of apoptosisBloodJune 18, 2015Schwartz C, Willebrand R, Huber S, Rupec RA, Wu D, Locksley R, Voehringer D.

(20) IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma modelRespiratory researchMarch 18, 2015Yao X, Wang W, Li Y, Huang P, Zhang Q, Wang J, Wang W, Lv Z, An Y, Qin J, et al.

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Recombinant Human IL-5 Protein, CF

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Recombinant Human IL-5 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-5 Protein, CF from R&D Systems, a Bio-Techne Brand

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