Recombinant Human B7-H2 Fc Chimera Protein, CF 165-B7-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human B7-H2 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $412.00Supplier Page View Company Product Page
Catalog Number165-B7-100
SpeciesHuman
Size100 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameB7-H2
NCBI Full Gene Nameinducible T cell costimulator ligand
NCBI Gene AliasesB7-H2, B7H2, CD275, B7RP-1, B7RP1, GL50, ICOS-L, B7h, ICOSL, LICOS
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 80-90 kDa, reducing conditions
Theoretical: 53.4 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human B7-H2 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta SyndromeFrontiers in immunologyJanuary 1, 2019Thauland TJ, Pellerin L, Ohgami RS, Bacchetta R, Butte MJ.indicated concentrations of anti-CD3ε (clone OKT3; Biolegend) and 2 μg/mL ICOS-ligand-Fc (R&D Systems; 165-B7-100). Soluble anti-CD28 (clone CD28.2; Biolegend) was added at 1 μg/mL. At day 4, the T cells were harvested

(2) Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid ArthritisJournal of immunology researchJanuary 1, 2018O'Dwyer R, Kovaleva M, Zhang J, Steven J, Cummins E, Luxenberg D, Darmanin-Sheehan A, Carvalho MF, Whitters M, Saunders K, et al.4 μg/ml rhB7-2/ CD86-Fc (R&D Systems cat. #141-B2-100) plus 500 ng/ml rhB7-H2-Fc (R&D Systems cat. #165-B7-100) was added in PBS at 100 μl/well and incubated for 3 h at room temperature followed by washes with PBS.

(3) Activin A programs the differentiation of human TFH cellsNature immunologyAugust 1, 2016Locci M, Wu JE, Arumemi F, Mikulski Z, Dahlberg C, Miller AT, Crotty S.

(4) Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cellsStem CellsApril 1, 2014Arcangeli ML, Bardin F, Frontera V, Bidaut G, Obrados E, Adams RH, Chabannon C, Aurrand-Lions M.

(5) ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activationBloodJune 28, 2012Weissmüller S, Semmler LY, Kalinke U, Christians S, Müller-Berghaus J, Waibler Z.

(6) ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naïve CD4+ T cellsEuropean journal of immunologyOctober 1, 2006Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, et al.

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B7-H2 Fc Chimera Protein

B7-H2 Fc Chimera Protein

B7-H2 Fc Chimera Protein

Recombinant Human B7-H2 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human B7-H2 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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