Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF 658-FR-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $427.00Supplier Page View Company Product Page
Catalog Number658-FR-050
SpeciesHuman
Molecule NameFGFR1 alpha
Size50 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 100-110 kDa, reducing conditions
Theoretical: 66 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
NCBI Full Gene Namefibroblast growth factor receptor 1
NCBI Gene AliasesHBGFR, HH2, FLT-2, FGFR-1, N-SAM, CEK, FGFBR, BFGFR, HRTFDS, KAL2, bFGF-R-1, OGD, CD331, FLT2, ECCL, FLG
Source/Expression SystemNS0-derived Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Development of Zalfermin, a Long-Acting Proteolytically Stabilized FGF21 AnalogJournal of Medicinal ChemistryJuly 25, 2024Kristian Sass-Ørum, Tina Møller Tagmose, Jørgen Olsen, Annika Sjölander, Per-Olof Wahlund, Dan Han, Andreas Vegge, Steffen Reedtz-Runge, Zhe Wang, Xiang Gao, et al.FGFR2c, FGFR3c, or FGFR4 fused to Fc (R&D Systems, cat. no. 685-FR-050, 712-FR-050, 766-FR-050, and 658-FR-050) were coupled to Protein A acceptor beads (PerkinElmer, cat. no. 6760137M). A signal, detected as an

(2) Soluble α-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney diseaseKidney internationalAugust 1, 2022Yanucil C, Kentrup D, Campos I, Czaya B, Heitman K, Westbrook D, Osis G, Grabner A, Wende AR, Vallejo J, et al.(969FG025/CF); human FGF21 (2539FG025/CF); human FGF23 (2604FG025/CF); mouse FGF23 (2629FG025/CF); human FGFR1c (658FR050); human FGFR2c (712FR050); human FGFR3c (766FR050); and human FGFR4 (685FR050). The sKL recombinant

(3) FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetesScientific reportsMay 5, 2022Yanucil C, Kentrup D, Li X, Grabner A, Schramm K, Martinez EC, Li J, Campos I, Czaya B, Heitman K, et al.(8409-FG-025/CF, R&D Systems), human soluble β-klotho (5889-KB-050/CF, R&D Systems), human FGFR1c (658-FR-050, R&D Systems); human FGFR2c (712-FR-050, R&D Systems); human FGFR3c (766-FR-050, R&D Systems); and human

(4) 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic MidlinePloS oneJanuary 1, 2015Chan WK, Howe K, Clegg JM, Guimond SE, Price DJ, Turnbull JE, Pratt T.

(5) A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruziInfection and immunityAugust 1, 2008Lu B, PereiraPerrin M.

(6) Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferationClinical cancer research : an official journal of the American Association for Cancer ResearchSeptember 1, 2005Martínez-Torrecuadrada J, Cifuentes G, López-Serra P, Saenz P, Martínez A, Casal JI.

(7) Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursorsDevelopment (Cambridge, England)March 1, 2004Kessaris N, Jamen F, Rubin LL, Richardson WD.

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Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human FGFR1 alpha (IIIc) Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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