Recombinant Human IL-22 Protein 782-IL-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-22 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $408.00Supplier Page View Company Product Page
Catalog Number782-IL-010
Size10 ug (also 50 ug, 200 ug, 1 mg)
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
SpeciesHuman
Source/Expression SystemE. coli-derived Recombinant Human IL-22 Protein
Molecule NameIL-22
Molecular Weight16.5 kDa
NCBI Full Gene Nameinterleukin 22
NCBI Gene Aliaseszcyto18, IL-TIF, IL-22, IL-21, IL-D110, TIFa, ILTIF, TIFIL-23
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitisNature communicationsApril 1, 2025Oliva M, Sarkar MK, March ME, Saeidian AH, Mentch FD, Hsieh CL, Tang F, Uppala R, Patrick MT, Li Q, et al.

(2) Epstein–Barr Virus BRRF1 Induces Butyrophilin 2A1 in Nasopharyngeal Carcinoma NPC43 Cells via the IL-22/JAK3-STAT3 PathwayInternational Journal of Molecular SciencesDecember 15, 2024Yue Liu, Ka Sin Lui, Zuodong Ye, Luo Chen, Allen Ka Loon Cheungtransfected with BRRF1 plasmid or control plasmid with Lipofectamine 3000 reagent. IL-22 (10 ng/mL, Cat no. 782-IL-010, R & D Systems, Minnneapolis, MN, USA) was also added to the cells for the experiment. Cells were harvested

(3) Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell ActivityCellular and Molecular Gastroenterology and HepatologyAugust 9, 2023Kristina R. Rivera, R. Jarrett Bliton, Joseph Burclaff, Michael J. Czerwinski, Jintong Liu, Jessica M. Trueblood, Caroline M. Hinesley, Keith A. Breau, Halston E. Deal, Shlok Joshi, et al.ng/mL,PeproTech,200-13 IL17A/F,100 μg/mL,100 ng/mL,BioLegend,580608 IL22,100 μg/mL,10 ng/mL,R&D Systems,782-IL-010 IL25,100 μg/mL,100 ng/mL,BioLegend,598902 Interleukin Stock and Working Concentrations

(4) Preclinical species gene expression database: Development and meta-analysisFrontiers in GeneticsJanuary 17, 2023Caitlin Krause, Kinga Suwada, Eric A. G. Blomme, Kenneth Kowalkowski, Michael J. Liguori, Prathap Kumar Mahalingaiah, Scott Mittelstadt, Richard Peterson, Lauren Rendino, Andy Vo, et al.cell culture conditions of 37°C and 5% CO2. Recombinant interleukin-22 (rIL-22) specific for human (Cat # 782-IL-010), rat (Cat # 1316-RL-010), and mouse (Cat # 582-ML-010) were purchased from R&D Systems and used as

(5) Smad7 Sustains Stat3 Expression and Signaling in Colon Cancer CellsCancersOctober 12, 2022Maresca C, Di Maggio G, Stolfi C, Laudisi F, Colella M, Pacifico T, Di Grazia A, Di Fusco D, Congiu D, Guida AM, et al.with IL-6 (20 ng/mL, catalog number 200-06, Peprotech, London, UK) or IL-22 (20 ng/mL, catalog number 782-IL-010, R&D Systems, Minneapolis, MN, USA) for 30 min. 2.2. Patients and Samples Both tumor and unaffected

(6) Enhanced In Vitro Expression of Filaggrin and Antimicrobial Peptides Following Application of Glycosaminoglycans and a Sphingomyelin-Rich Lipid ExtractVeterinary sciencesJune 27, 2022Segarra S, Naiken T, Garnier J, Hamon V, Coussay N, Bernard FX.

(7) Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cellsThe Journal of biological chemistryFebruary 1, 2022Carroll DJ, Burns MWN, Mottram L, Propheter DC, Boucher A, Lessen GM, Kumar A, Malaker SA, Xing C, Hooper LV, et al.

(8) Expanded IL-22⁺ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with DyslipidaemiaImmune networkDecember 1, 2021Min HK, Moon J, Lee SY, Lee AR, Lee CR, Lee J, Kwok SK, Cho ML, Park SH.

(9) PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in PsoriasisCellsOctober 2, 2021Mercurio L, Morelli M, Scarponi C, Scaglione GL, Pallotta S, Albanesi C, Madonna S.

(10) miR-21-3p/IL-22 Axes Are Major Drivers of Psoriasis Pathogenesis by Modulating Keratinocytes Proliferation-Survival Balance and Inflammatory ResponseCellsSeptember 26, 2021Abdallah F, Henriet E, Suet A, Arar A, Clemençon R, Malinge JM, Lecellier G, Baril P, Pichon C.stimulation was achieved in the same medium for 24 h with 50 ng/mL recombinant human IL-22 (R&D systems, # 782-IL010). 2.6. Cell Transfection The transfection experiments were performed on 50% confluent cells in 12-well

(11) Tofacitinib downregulates antiviral immune defence in keratinocytes and reduces T cell activationArthritis research & therapyMay 21, 2021Hawerkamp HC, Domdey A, Radau L, Sewerin P, Oláh P, Homey B, Meller S.

(12) Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/IκBα pathwayArthritis research & therapySeptember 23, 2020Min HK, Won JY, Kim BM, Lee KA, Lee SJ, Lee SH, Kim HR, Kim KW.

(13) Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infectionMucosal immunologyJanuary 1, 2020Hebert KD, Mclaughlin N, Galeas-Pena M, Zhang Z, Eddens T, Govero A, Pilewski JM, Kolls JK, Pociask DA.

(14) Interleukin-22 Induces the Infiltration of Visceral Fat Tissue by a Discrete Subset of Duffy Antigen Receptor for Chemokine-Positive M2-Like Macrophages in Response to a High Fat DietCellsDecember 6, 2019Kim EY, Noh HM, Choi B, Park JE, Kim JE, Jang Y, Lee HK, Chang EJ.

(15) TNF-α and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytesJournal of dermatological scienceOctober 1, 2019Sugihara S, Sugimoto S, Tachibana K, Kobashi M, Nomura H, Miyake T, Hirai Y, Yamasaki O, Morizane S.

(16) Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin ModelsCellsSeptember 15, 2019Chamcheu JC, Esnault S, Adhami VM, Noll AL, Banang-Mbeumi S, Roy T, Singh SS, Huang S, Kousoulas KG, Mukhtar H.

(17) IL-22 Binding Protein Promotes the Disease Process in Multiple SclerosisJournal of immunology (Baltimore, Md. : 1950)August 15, 2019Lindahl H, Guerreiro-Cacais AO, Bedri SK, Linnerbauer M, Lindén M, Abdelmagid N, Tandre K, Hollins C, Irving L, Glover C, et al.

(18) IL-36γ regulates mediators of tissue homeostasis in epithelial cellsCytokineJuly 1, 2019Heath JE, Scholz GM, Veith PD, Reynolds EC.

(19) Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytesCell death & diseaseMarch 20, 2019Sun S, Zhang X, Xu M, Zhang F, Tian F, Cui J, Xia Y, Liang C, Zhou S, Wei H, et al.

(20) R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferationScientific reportsMarch 11, 2019Abdallah F, Lecellier G, Raharivelomanana P, Pichon C.(TLR5 ligand, invivogen catalog # tlrl-stfla) and/or 50 ng/mL recombinant human IL-22 (R&D systems, #782-IL010). Cell metabolic activity. Cell Proliferation kit II (XTT- Roche) allows to evaluate the cell metabolic

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(1)

2/1/2016IL-22 Standard for Human IL-22 ELISA Ritu SarinHuman IL-22 was detected from in vitro cultured CD4+ memory cells under various conditions.

Recombinant Human IL-22 Protein

IL-22 Protein

IL-22 Protein

IL-22 Protein

IL-22 Protein

Recombinant Human IL-22 Protein from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

Citations (71)

Reviews

Recombinant Human IL-22 Protein from R&D Systems, a Bio-Techne Brand

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