Active Cathepsin C/DPPI Protein 2336-CY-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemActive Cathepsin C/DPPI Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $528.00Supplier Page View Company Product Page
Catalog Number2336-CY-010
SpeciesMouse
FormatSupplied as a 0.2 µm filtered solution in MES, NaCl and Glycerol
Size10 ug
Molecule NameCathepsin C/DPPI
NCBI Full Gene Namecathepsin C
NCBI Gene AliasesDPPI, CatC, PLS, PALS, JP, JPD, HMS, PDON1, DPP1, DPP-I, CPPI
Molecular WeightObserved: 8 kDa and 19-29 kDa, reducing conditions
Theoretical: 13 kDa (Exclusion domain), 18 kDa (Heavy chain), and 9 kDa (Light chain)
ApplicationsEnzyme Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse Active Cathepsin C/DPPI Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

Specifications/Features

Available conjugates: Sizes Available: 10 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cellsFrontiers in pharmacologyJanuary 1, 2024Sutton VR, Watt SV, Akhlaghi H, Cipolla DC, Chen KJ, LaSala D, McDonald PP, Beavis PA, Munoz I, Hodel AW, et al.

(2) A Breath-Based In Vitro Diagnostics for Lower Respiratory Tract InfectionmedRxiv : the preprint server for health sciencesSeptember 18, 2023Chen D, Mirski MA, Caton ER, Kiser KM, Haddaway CR, Cetta MS, Chen S, Bryden WA, McLoughlin M.

(3) N-Acetyldopamine dimers from Oxya chinensis sinuosa attenuates lipopolysaccharides induced inflammation and inhibits cathepsin C activityComputational and structural biotechnology journalJanuary 1, 2022Bahuguna A, Khaket TP, Bajpai VK, Shukla S, Park I, Na M, Huh YS, Han YK, Kang SC, Kim M.

(4) Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human OligodendrocytesFrontiers in immunologyJanuary 1, 2022Jamann H, Cui QL, Desu HL, Pernin F, Tastet O, Halaweh A, Farzam-Kia N, Mamane VH, Ouédraogo O, Cleret-Buhot A, et al.in activation buffer (50 mM MES, 50 mM NaCl, pH = 5.5) with 10 μg/ml cathepsin D (R& D Systems, Cat# 2336-CY-010) for 4 h at 37°C. After activation, granzyme B was diluted at indicated concentrations in assay buffer

(5) Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesisCellJune 10, 2021Cui C, Chakraborty K, Tang XA, Zhou G, Schoenfelt KQ, Becker KM, Hoffman A, Chang YF, Blank A, Reardon CA, et al.mouse ELANE,R&D Systems,Cat# 4517-SE-010 Recombinant mouse active Cathepsin C/DPPI,R&D Systems,Cat# 2336-CY-010 Recombinant human SLPI protein,R&D Systems,Cat# 1274-PI Human native A1AT,Athens Research & Technology,Cat#

(6) Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancerImmunityMay 11, 2021Tello-Lafoz M, Srpan K, Sanchez EE, Hu J, Remsik J, Romin Y, Calò A, Hoen D, Bhanot U, Morris L, et al.B,Biolegend,Cat#554804 R&D Systems™ Mouse Active Cathepsin C/DPPI Recombinant Protein,R&D Systems™,Cat#2336CY010 Alexa Fluor™ 594 Phalloidin,"Thermo Fisher Scientific, Invitrogen",Cat#A12381 DAPI,Thermo Fisher Scientific,Cat#D1306 CellMask™ Orange Plasma membrane Stain

(7) Distinct roles for cysteine cathepsin genes in multistage tumorigenesisGenes & developmentMarch 1, 2006Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA.

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Active Cathepsin C/DPPI Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Active Cathepsin C/DPPI Protein from R&D Systems, a Bio-Techne Brand

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