Recombinant Human IL-5 Protein 205-IL-005 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-5 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $237.00Supplier Page View Company Product Page
Catalog Number205-IL-005
Size5 ug (also 25 ug)
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Molecular WeightObserved: 11-16 kDa, reducing conditions
Theoretical: 13 kDa (monomer)
Conjugate/TagUnconjugated
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
SpeciesHuman
Molecule NameIL-5
Source/Expression SystemSf 21 (stably transfected)-derived Recombinant Human IL-5 Protein
NCBI Full Gene Nameinterleukin 5
NCBI Gene AliasesIL-5, EDF, TRF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-13 Promotes Accumulation of Esophageal Epithelial Mitochondria With Translational Implications for Eosinophilic EsophagitisCellular and Molecular Gastroenterology and HepatologyApril 27, 2026Jazmyne L. Jackson, Reshu Saxena, Mary Grace Murray, Abigail J. Staub, Courtney Worrell, Jasmine Cruz, No’ad Shanas, Alena Klochkova, Travis H. Bordner, John M. Crespo, et al.Cat# 210-TA-005/CF; 40 ng/mL), IL-4 (R&D Systems, Cat# 204-IL-010; 10 ng/mL), IL-5 (R&D Systems, Cat# 205-IL-005; 10 ng/mL), IL-13 (R&D Systems, Cat# 213-ILB-005/CF; 10 ng/mL), or IL-1β (R&D Systems, Cat# 201-lB-005;

(2) Evidence for a Role of the Long Non-Coding RNA ITGB2-AS1 in Eosinophil Differentiation and FunctionsCellsNovember 22, 2024Fettrelet T, Hosseini A, Wyss J, Boros-Majewska J, Stojkov D, Yousefi S, Simon HU.

(3) Eosinophils mitigate intestinal fibrosis while promoting inflammation in a chronic DSS colitis model and co-culture model with fibroblastsScientific reportsNovember 7, 2024Jacobs I, Deleu S, Ke BJ, Cremer J, Dilissen E, De Hertogh G, Martens T, Vanden Berghe P, Matteoli G, Vermeire S, et al.eosinophil isolation, eosinophils were either activated using 0.3ng/mL recombinant human IL-5 (R&D systems, 205-IL-005) or cultured without activation. Several conditions were established; fibroblasts were cultured in RPMI-5

(4) Determining the toxicological effects of indoor air pollution on both a healthy and an inflammatory-comprised model of the alveolar epithelial barrier in vitroParticle and Fibre ToxicologyMay 17, 2024Kirsty Meldrum, Stephen J. Evans, Michael J. Burgum, Shareen H. Doak, Martin J. D. CliftdTHP-1 cells) prior to exposures [41]. Inflamed model characterisation Interleukin (IL)-5 (Cat no. 205-IL-005), IL-13 (Cat no. 213-ILB-005) and IL-4 (Cat no. 204-IL-010) from R&D systems (Biotechne, Abingdon, UK)

(5) Localization and RNA Interference-Driven Inhibition of a Brugia malayi-Encoded Interleukin-5 Receptor Binding ProteinInfection and immunityMay 19, 2022Mejia R, Bennuru S, Oksov Y, Lustigman S, Munirathinam G, Kalyanasundaram R, Nutman TB.

(6) The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in miceThe Journal of experimental medicineApril 4, 2022Diny NL, Schonfeldova B, Shapiro M, Winder ML, Varsani-Brown S, Stockinger B.(#61870-010; Thermo Fisher Scientific) with penicillin/streptomycin (#P4333; Sigma-Aldrich) and 10 ng/ml IL5 (#205-IL-005; R&D Systems) at 75,000 cells per well in duplicate and stimulated for 4 h with DMSO, 5 nM FICZ, or

(7) Enhanced 15-Lipoxygenase 1 Production is Related to Periostin Expression and Eosinophil Recruitment in Eosinophilic Chronic RhinosinusitisBiomoleculesNovember 18, 2020Imoto Y, Takabayashi T, Sakashita M, Kato Y, Yoshida K, Kidoguchi M, Koyama K, Adachi N, Kimura Y, Ogi K, et al.

(8) T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal InflammationCell reportsJune 30, 2020Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C.

(9) Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separationBMC research notesApril 10, 2020Cao Y, Shin S, Carroll DJ, O'Sullivan JA, Bochner BS.

(10) Fibrinogen Is a Specific Trigger for Cytolytic Eosinophil DegranulationJournal of immunology (Baltimore, Md. : 1950)January 15, 2020Coden ME, Loffredo LF, Walker MT, Jeong BM, Nam K, Bochner BS, Abdala-Valencia H, Berdnikovs S.

(11) The role of IL-36γ and its regulation in eosinophilic inflammation in allergic rhinitisCytokineMay 1, 2019Qin X, Liu M, Zhang S, Wang C, Zhang T.

(12) Interleukin-5 suppresses Vascular Endothelial Growth Factor-induced angiogenesis through STAT5 signalingCytokineOctober 1, 2018Bucher F, Lee J, Shin S, Kim MS, Oh YS, Ha S, Zhang H, Yea K.

(13) Myeloid-derived growth factor is a resident endoplasmic reticulum proteinThe Journal of biological chemistryAugust 24, 2018Bortnov V, Annis DS, Fogerty FJ, Barretto KT, Turton KB, Mosher DF.

(14) IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophilsCell death & diseaseMay 1, 2018Zellweger F, Buschor P, Hobi G, Brigger D, Dahinden CA, Villiger PM, Eggel A.

(15) Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostinPloS oneJanuary 1, 2018Barretto KT, Swanson CM, Nguyen CL, Annis DS, Esnault SJ, Mosher DF, Johansson MW.

(16) IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migrationClinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyOctober 1, 2017Johansson MW, Khanna M, Bortnov V, Annis DS, Nguyen CL, Mosher DF.

(17) Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of AllergenJournal of immunology (Baltimore, Md. : 1950)August 1, 2017Schroeder JT, Bieneman AP.

(18) Human eosinophils constitutively express a unique serine protease, PRSS33Allergology international : official journal of the Japanese Society of AllergologyJuly 1, 2017Toyama S, Okada N, Matsuda A, Morita H, Saito H, Fujisawa T, Nakae S, Karasuyama H, Matsumoto K.

(19) Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytesImmunologyJanuary 1, 2017Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota SI, Ota Y, Mitoma H, Akahoshi M, Mori Y, Iwasaki H, et al.

(20) The effect of hepatocyte growth factor on secretory functions in human eosinophilsCytokineDecember 1, 2016Yamauchi Y, Ueki S, Konno Y, Ito W, Takeda M, Nakamura Y, Nishikawa J, Moritoki Y, Omokawa A, Saga T, et al.

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Recombinant Human IL-5 Protein

IL-5 Protein

IL-5 Protein

IL-5 Protein

IL-5 Protein

Recombinant Human IL-5 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-5 Protein from R&D Systems, a Bio-Techne Brand

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