Recombinant Mouse IFN-gamma Protein 485-MI-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse IFN-gamma Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $503.00Supplier Page View Company Product Page
Catalog Number485-MI-100
SpeciesMouse
Molecule NameIFN-gamma
Size100 ug
Source/Expression SystemE. coli-derived Recombinant Mouse IFN-gamma Protein
NCBI Full Gene Nameinterferon gamma
NCBI Gene AliasesIFN-g, Ifg, If2f
FormatLyophilized from a 0.2 µm filtered solution in Sodium Succinate, Mannitol,Tween® 80 and TCEP with BSA as a carrier protein
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 11-12 kDa, reducing conditions
Theoretical: 15.6 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodesImmunityApril 20, 2026Jafar Al Souz, Yulong Wei, Can Cui, Rihao Qu, Jin-Young Choi, Fang Wang, Steven J. Moioffer, Julia Barrett, Irene Chernova, Manvitha Nadella, et al.Cell Stain Kit,Invitrogen,Cat#L34966 Recombinant Mouse IFN-gamma Protein with carrier,R&D Systems,Cat#485-MI-100 Recombinant Mouse TNF-alpha (aa 80–235) Protein with carrier,R&D Systems,Cat#410-MT-025 Recombinant Mouse IL-10 Protein

(2) Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in miceNature MicrobiologyMarch 19, 2026Li Yang, Robert C. Peery, Shirui Zhou, Xiaomin Chen, Leah M. Farmer, Fabiola Gutierrez, Stephanie Fowler, Lanjing Zhang, Julia M. Salamat, Karen Riggins, et al.days. For IFNγ treatment, GF-derived organoids were incubated with recombinant mouse IFNγ (R&D Systems, 485-MI-100) at 0.1 ng ml−1 for 0, 24, 48, 72 or 96 h before collection. For single-agent treatment, organoids were

(3) MAPK Pathway Mutations Emerge in Mutant-IDH1 Inhibitor-Resistant Cholangiocarcinoma and Attenuate the Interferon ResponseClinical Cancer ResearchMarch 2, 2026Jinkai Wan, Hatice Duygu Saatcioglu, Haley Ellis, Elia Aguado-Fraile, Qin Xu, Hiroshi Kondo, Robert T. Manguso, Ilaria Gritti, Bryanna L. Norden, Carolina Noble, et al.(Recombinant Human IFN-gamma Protein, R&D Systems, cat. #285-IF-100; or Recombinant Mouse IFN-gamma Protein, R&D Systems, cat. #485-MI-100). Note: RAS inhibitors were added at least 6 hours before IFNγ treatment to pre-reduce MAPK signaling. Immunoblotting Cell

(4) Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in post-streptococcal encephalitisbioRxivFebruary 7, 2026Charlotte R. Wayne, Ugur Akcan, Travis E. Faust, Violetta Duran-Laforet, Danny Jamoul, Luca Bremner, Nicole Ampatey, Büşra T. Akcan, Sarah J. Ho, Bogoljub Ciric, et al.switched to 2% FBS without growth factor supplements. Media containing either mouse IFNγ (R&D Systems, 485-MI-100), mouse IL-17A (R&D Systems, 7956-ML-025), mouse GM-CSF (R&D Systems, 415-ML-010) or vehicle (PBS with

(5) CTRP6 as a negative regulator of anti-inflammatory M2 macrophage polarizationImmunometabolism (Cobham)October 27, 2025Jeevotham Senthil Kumar, Emma Kempton, Muhammad Zubair Mehboob, Dingbo Lin, Xia Lei100 ng/mL LPS (00-4976-93, Invitrogen, Thermo Fisher Scientific, Waltham, MA, USA) and 20 ng/mL IFNγ (485-MI-100, R&D Systems, Minneapolis, MN, USA) for M1, and 20 ng/mL IL-4 (404-ML-010, R&D Systems, Minneapolis,

(6) Decoding adult murine pancreatic islet cell diversity through cell type-resolved proteomics and phosphoproteomicsCommun BiolOctober 17, 2025Marvin Thielert, Adrian Villalba, Vincenth Brennsteiner, Maria Wahle, Constantin Ammar, Andreas-David Brunner, Alexis Fouque, Chloé Lourenço, Masaya Oshima, Latif Rachdi, et al.(#15140122, ThermoFisher Scientific). Next, islets were treated with or without IFNγ (5 ng/ml) for 20 h (#485-MI-100, R&D Systems, Minneapolis, MN, USA). For IFNγ treatment, pooled islets from 3 mice per condition were

(7) Leukocyte-type 12/15-lipoxygenase is essential for timely inflammation-resolution and effective tissue regeneration following skeletal muscle injuryMolecular metabolismOctober 1, 2025Sharma B, Lu X, Rehman H, Figueiredo VC, Davis C, Van Remmen H, Kuang S, Brooks SV, Maddipati KR, Markworth JF.

(8) Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophilseLifeSeptember 12, 2025Ravesloot-Chavez MM, Van Dis E, Fox D, Anaya-Sanchez A, Espich S, Nguyenla XH, Rawal S, Samani H, Ballinger M, Thomas HF, et al.

(9) Vector-free intra-airway in vivo epigenetic editingTrends in biotechnologySeptember 1, 2025Yano N, Ramar M, Gregory DJ, Fedulov AV.

(10) Macrophage–Kruppel-Like Transcription Factor 6 Signaling Promotes Experimental AtherogenesisThe American Journal of PathologySeptember 1, 2025Hang Pong Ng, Atif Zafar, Rachel Diamond-Zaluski, Gun-Dong Kim, Kartik Bhat, Owen Meadows, Yashwant Pantra, E. Ricky Chan, Jonathan D. Smith, Ganapati H. Mahabeleshwarfactor (416-ML), mouse tumor necrosis factor (TNF)-α protein (210-TA-100), and mouse interferon-γ (485-MI-100) were obtained from R&D Systems (Minneapolis, MN). The high-glucose Dulbecco's modified Eagle's medium

(11) Evidence that mitochondria in macrophages are destroyed by microautophagyNature communicationsAugust 30, 2025Lu SL, Chen S, Noda K, Li Y, Tsai CY, Omori H, Kato Y, Zhang Z, Chen B, Tokuda K, et al.

(12) Endolysosomal damage surveillance enables rapid inflammasome sensing of pathogensCell reportsAugust 26, 2025Shivcharan S, Younis DA, Wright SS, Wang C, Behl B, Shumba P, Delgado KN, Chawla AK, Alto NM, Panjwani N, et al.16008 Carbenicillin antibiotic,Boston Bioproducts,Cat# P-760 Recombinant mouse IFN-γ,R&D Systems,Cat# 485-MI-100 Gentamicin,Gibco,Cat#15750-060 Streptomycin sulfate,Sigma-Aldrich,Cat# S6501-100G Clarity ECL HRP

(13) Inflammatory cytokine interleukin-18 prevents murine miscarriage by inducing appropriate inflammationScientific reportsAugust 21, 2025Horii Y, Ino H, Sasaki F, Ishibashi M, Koike E, Kawamoto Y, Flavell RA, Ohashi R, Suzuki S, Negishi Y, et al.

(14) Inflammatory Oxidative Stress Compounds Inhibit Insulin Secretion through Rapid Protein CarbonylationbioRxiv : the preprint server for biologyJuly 26, 2025Saunders EF, Schultz KR, Lowe I, Anderson AL, Bikkumalla VS, Soto D, Tran NY, Baumel-Alterzon S, Knight JD, Shearn CT.

(15) MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancerCell reports. MedicineJuly 15, 2025Del Rey-Vergara R, Galindo-Campos MA, Rocha P, Carpes M, Martínez C, Masfarré L, Menéndez S, Quimis F, Rossell A, Iñañez A, et al.routinely tested for mycoplasma. Method details Drugs and recombinant proteins Recombinant mouse IFN-γ (485-MI-100) and recombinant mouse HGF (2207-HG-025) were purchased from R&D Systems and reconstituted in sterile

(16) Molecular Mechanisms of Aminoglycoside-Induced Ototoxicity in Murine Auditory Cells: Implications for Otoprotective Drug DevelopmentInternational journal of molecular sciencesJuly 13, 2025Hsieh CY, Lin JN, Chou YF, Hsu CJ, Chen PR, Wen YH, Wu CC, Sun CH.

(17) Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining PropertiesCancer researchJuly 2, 2025Cumming J, Maneshi P, Dongre M, Alsaed T, Dehghan-Nayeri MJ, Ling A, Pietras K, Patthey C, Öhlund D.

(18) Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunityNatureJuly 1, 2025Faust Akl C, Andersen BM, Li Z, Giovannoni F, Diebold M, Sanmarco LM, Kilian M, Fehrenbacher L, Pernin F, Rone JM, et al.(R&D Systems, 7666-MB-005), 100 ng ml−1 IL-15 (PeproTech, 210–15) and 50 ng ml−1 IFN-γ (R&D Systems, 485-MI-100). Isolation, culture and stimulation of primary mouse neurons Primary neurons were isolated from mouse

(19) Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapiesNature communicationsJuly 1, 2025Damei I, Caidi A, Auclin E, Adam J, Mella S, Hasan M, Tartour E, Robert C, Corgnac S, Mami-Chouaib F.functional experiments MC38-E tumour cells were preincubated for 48 h with IFNγ (20 ng/mL, R&D systems, 485-MI-100) and cocultured for 4 h with CD45+ TIL in the presence of Brefeldin A (Invitrogen 00-4506-51, 1/1000),

(20) Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for diseasePLOS PathogensJune 30, 2025Panjaporn Chaichana, Naphat Satapoomin, Chitrasak Kullapanich, Suthida Chuenklin, Aisha Mohammad, Manutsanun Inthawong, Erin E. Ball, Thomas P. Burke, Piyanate Sunyakumthorn, Jeanne Saljeleft unstimulated or stimulated for 18 hours with 400 U/ml of recombinant mouse (R&D Systems, cat# 485-MI-100, USA) or human IFN-γ (R&D Systems, cat# 285-IF-100, USA) for BMDM and human primary macrophages, respectively.

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Recombinant Mouse IFN-gamma Protein

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IFN-gamma Protein

IFN-gamma Protein

Recombinant Mouse IFN-gamma Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse IFN-gamma Protein from R&D Systems, a Bio-Techne Brand

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