Recombinant Mouse Netrin-1 Protein, CF 1109-N1-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse Netrin-1 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $449.00Supplier Page View Company Product Page
Catalog Number1109-N1-025/CF
Size25 ug
ApplicationsBinding Activity
FormatLyophilized from a 0.2 µm filtered solution in HEPES, NaCl with Trehalose
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 83 kDa, reducing conditions
Theoretical: 68.2 kDa
Conjugate/TagUnconjugated
SpeciesMouse
Molecule NameNetrin-1
Source/Expression SystemNS0-derived Recombinant Mouse Netrin-1 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namenetrin 1
NCBI Gene AliasesNetrin-1

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic EncephalopathyAdvanced ScienceAugust 11, 2025Yang Zhou, Jia‐Xin Kou, Kai Zheng, Zi‐Xuan Guo, Hong‐Wei Fan, Wen‐Lian Li, Lu‐Lu Chu, Jing‐Wen Yin, Li‐Jie Liu, Nadezhda Brazhe, et al.102 , 103 ] Intranasal administration of recombinant mouse Netrin‐1 (rNTN‐1; R&D Systems, Cat# 1109‐N1‐025/CF) was performed once daily for seven consecutive days. Mice were gently restrained in a supine position

(2) Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneuronsMolecular psychiatryApril 1, 2025Eid L, Lokmane L, Raju PK, Tene Tadoum SB, Jiang X, Toulouse K, Lupien-Meilleur A, Charron-Ligez F, Toumi A, Backer S, et al.#8616-SL-050, Cedarlane, Burlington, ON, Canada), recombinant mouse Netrin-1 protein (250 ng/ml; Cat. #1109-N1-025/CF, Bio-Techne/R&D Systems, Minneapolis, MN, USA), recombinant mouse EphA4-Fc chimera protein (10 µg/ml;

(3) Netrin-1 Promotes the Immunosuppressive Activity of MDSCs in Colorectal CancerCancer immunology researchMay 3, 2023Xia X, Mao Z, Wang W, Ma J, Tian J, Wang S, Yin K.

(4) Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage ResponseNature communicationsApril 10, 2023Ramalingam P, Gutkin MC, Poulos MG, Tillery T, Doughty C, Winiarski A, Freire AG, Rafii S, Redmond D, Butler JM.

(5) Tace/ADAM17 is a bi-directional regulator of axon guidance that coordinates distinct Frazzled and Dcc receptor signaling outputsCell reportsDecember 6, 2022Zang Y, Chaudhari K, Bashaw GJ.

(6) Allosteric potentiation of GABA(A) receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasisCell reportsNovember 1, 2022Chan ES, Ge Y, So YW, Bai YF, Liu L, Wang YT.

(7) Spinal TRPA1 Contributes to the Mechanical Hypersensitivity Effect Induced by Netrin-1International journal of molecular sciencesJune 14, 2022Wei H, Ailanen L, Morales M, Koivisto A, Pertovaara A.recording sites verified in coronal brain sections. 4.7. Drugs Netrin-1 (recombinant mouse netrin # 1109-N1-025/CF) was purchased from Bio-Techne Ltd. (Abingdon, UK), dissolved in saline, and administered at a dose

(8) The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult miceStem cell researchApril 1, 2022Barroca V, Racine C, Pays L, Fouchet P, Coureuil M, Allemand I.

(9) Endothelial Unc5B controls blood-brain barrier integrityNature communicationsMarch 4, 2022Boyé K, Geraldo LH, Furtado J, Pibouin-Fragner L, Poulet M, Kim D, Nelson B, Xu Y, Jacob L, Maissa N, et al.

(10) A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosisNature communicationsAugust 11, 2021Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, et al.

(11) Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologiesScience advancesApril 1, 2021Chen G, Kang SS, Wang Z, Ahn EH, Xia Y, Liu X, Sandoval IM, Manfredsson FP, Zhang Z, Ye K.

(12) Inhibition of vascular adventitial remodeling by netrin-1 in diabetic ratsThe Journal of endocrinologyMarch 1, 2020Wang HF, Yu QQ, Zheng RF, Xu M.h, intraperitoneally) (Ranganathan et al. 2015). Recombinant soluble netrin-1 was purchased from R&D Systems, USA (1109-N1-025/CF). In the first 6 weeks, rats in both untreated and treated diabetes group were given HFD alone and rats in

(13) On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in AxonsCell reportsDecember 10, 2019Shigeoka T, Koppers M, Wong HH, Lin JQ, Cagnetta R, Dwivedy A, de Freitas Nascimento J, van Tartwijk FW, Ströhl F, Cioni JM, et al.

(14) A Spatiotemporal Sequence of Sensitization to Slits and Semaphorins Orchestrates Commissural Axon NavigationCell reportsOctober 8, 2019Pignata A, Ducuing H, Boubakar L, Gardette T, Kindbeiter K, Bozon M, Tauszig-Delamasure S, Falk J, Thoumine O, Castellani V.

(15) The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expressionNucleic acids researchMay 21, 2019Zhuang M, Li X, Zhu J, Zhang J, Niu F, Liang F, Chen M, Li D, Han P, Ji SJ.

(16) Disease-associated mutations in human TUBB3 disturb netrin repulsive signalingPloS oneJanuary 1, 2019Shao Q, Yang T, Huang H, Majumder T, Khot BA, Khouzani MM, Alarmanazi F, Gore YK, Liu G.

(17) Netrin-1 attenuates brain injury after middle cerebral artery occlusion via downregulation of astrocyte activation in miceJournal of neuroinflammationSeptember 18, 2018He X, Liu Y, Lin X, Yuan F, Long D, Zhang Z, Wang Y, Xuan A, Yang GY.

(18) Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptorScientific reportsApril 16, 2018Zhang Y, Chen P, Di G, Qi X, Zhou Q, Gao H.

(19) Netrin 1 mediates protective effects exerted by insulin-like growth factor 1 on cochlear hair cellsNeuropharmacologyJune 1, 2017Yamahara K, Nakagawa T, Ito J, Kinoshita K, Omori K, Yamamoto N.

(20) Functional Roles of Netrin-1 in Osteoblast DifferentiationIn vivo (Athens, Greece)May 1, 2017Sato T, Kokabu S, Enoki Y, Hayashi N, Matsumoto M, Nakahira M, Sugasawa M, Yoda T.

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Recombinant Mouse Netrin-1 Protein, CF

Netrin-1 Protein

Netrin-1 Protein

Recombinant Mouse Netrin-1 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse Netrin-1 Protein, CF from R&D Systems, a Bio-Techne Brand

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