Recombinant Mouse IL-1 beta/IL-1F2 Protein, CF 401-ML-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse IL-1 beta/IL-1F2 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $303.00Supplier Page View Company Product Page
Catalog Number401-ML-005/CF
SpeciesMouse
Molecule NameIL-1 beta/IL-1F2
Size5 ug (also 10 ug, 25 ug, 100 ug)
FormatSupplied as a 0.2 µm filtered solution in PBS
NCBI Full Gene Nameinterleukin 1 beta
NCBI Gene AliasesIL-1beta, Il-1b
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight17 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse IL-1 beta/IL-1F2 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -20 to -70 °C under sterile conditions after opening

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2Bone researchJanuary 2, 2025Wei K, Zhou C, Shu Z, Shang X, Zou Y, Zhou W, Xu H, Liang Y, Ma T, Sun X, et al.treatment. Materials and methods Reagents and antibodies Recombinant mouse IL-1β was sourced from R&D Systems (401-ML-005/CF, Minneapolis, MN, USA). Lipofectamine 3000 was obtained from Invitrogen (L3000008, Waltham, MA, USA).

(2) Transcription factor TCF1 binds to RORγt and orchestrates a regulatory network that determines homeostatic Th17 cell stateImmunityNovember 1, 2024Davide Mangani, Ayshwarya Subramanian, Linglin Huang, Hanning Cheng, S. Harsha Krovi, Yufan Wu, Dandan Yang, Thais G. Moreira, Giulia Escobar, Alexandra Schnell, et al.control (MOPC-21),BioXcell,Cat# BE0083 "Chemicals, peptides, and recombinant proteins",, IL-1b,,Cat# 401-ML-005/CF IL-6,R&D Systems,Cat # 406-ML-005/CF IL-23,R&D Systems,Cat# 11269-ML-010 TGFb1,R&D Systems,Cat# 7754-BH-005/CF Myelin

(3) Inhibition of histone lysine demethylase 6A promotes chondrocytic activity and attenuates osteoarthritis development through repressing H3K27me3 enhancement of Wnt10aThe international journal of biochemistry & cell biologyMay 1, 2023Lian WS, Wu RW, Ko JY, Chen YS, Wang SY, Jahr H, Wang FS.

(4) Methods for Imaging Inflammation and Transendothelial Migration in Vivo and ex VivoCurrent ProtocolsApril 20, 2023Vivienne Fang, Maureen E. Haynes, Vanessa Hayashi, Erika Arias, Jeremy A. Lavine, David P. Sullivan, William A. Mullercalcium & magnesium (CORNING, lot 26321007) Recombinant mouse interleukin-1β (IL-1β) (R&D Systems, 401-ML-005/CF) Ketamine hydrochloride (Covetrus, NDC# 11695-0703-1) Xylazine (Akorn Inc., NDC# 59399-110-20) Anti-PECAM

(5) Crosstalk between ILC2s and Th2 cells varies among mouse modelsCell reportsFebruary 28, 2023Gurram RK, Wei D, Yu Q, Butcher MJ, Chen X, Cui K, Hu G, Zheng M, Zhu X, Oh J, et al.

(6) Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory ChallengebioRxiv : the preprint server for biologyFebruary 11, 2023Schafer CM, Martin-Almedina S, Kurylowicz K, Dufton N, Osuna-Almagro L, Wu ML, Johnson CF, Shah AV, Haskard DO, Buxton A, et al.

(7) Modulation of Skin Inflammatory Responses by Aluminum AdjuvantPharmaceuticsFebruary 8, 2023Liao Y, Sun L, Nie M, Li J, Huang X, Heng S, Zhang W, Xia T, Guo Z, Zhao Q, et al.

(8) Identification of astrocyte regulators by nucleic acid cytometryNatureFebruary 1, 2023Clark IC, Wheeler MA, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, et al.

(9) RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1αbioRxiv : the preprint server for biologyJanuary 7, 2023Dumesic PA, Wilensky SE, Bose S, Van Vranken JG, Gygi SP, Spiegelman BM.

(10) Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolismScience advancesJanuary 4, 2023Wang G, Sweren E, Andrews W, Li Y, Chen J, Xue Y, Wier E, Alphonse MP, Luo L, Miao Y, et al.

(11) SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysisJournal of advanced researchJanuary 1, 2023Cheng CK, Lin X, Pu Y, Tse JKY, Wang Y, Zhang CL, Cao X, Lau CW, Huang J, He L, et al.

(12) Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearanceMolecular neurodegenerationDecember 13, 2022Zia S, Hammond BP, Zirngibl M, Sizov A, Baaklini CS, Panda SP, Ho MFS, Lee KV, Mainali A, Burr MK, et al.

(13) Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respirationMolecular metabolismDecember 1, 2022Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, et al.

(14) NR4A1 agonist cytosporone B attenuates neuroinflammation in a mouse model of multiple sclerosisNeural regeneration researchDecember 1, 2022Yu HZ, Zhu BQ, Zhu L, Li S, Wang LM.

(15) IL-3 regulates the differentiation of pathogenic Th17 cellsEuropean journal of immunologyNovember 1, 2022Rani L, Kumar A, Karhade J, Pandey G, Guha A, Mishra GC, Wani MR.

(16) Montelukast reduces grey matter abnormalities and functional deficits in a mouse model of inflammation-induced encephalopathy of prematurityJournal of neuroinflammationOctober 29, 2022Yates AG, Kislitsyna E, Alfonso Martin C, Zhang J, Sewell AL, Goikolea-Vives A, Cai V, Alkhader LF, Skaland A, Hammond B, et al.

(17) Desmoglein-2 is important for islet function and β-cell survivalCell death & diseaseOctober 29, 2022Myo Min KK, Rojas-Canales D, Penko D, DeNichilo M, Cockshell MP, Ffrench CB, Thompson EJ, Asplund O, Drogemuller CJ, Prasad RB, et al.

(18) Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesisNatureOctober 1, 2022Filliol A, Saito Y, Nair A, Dapito DH, Yu LX, Ravichandra A, Bhattacharjee S, Affo S, Fujiwara N, Su H, et al.

(19) A cannabidiol aminoquinone derivative activates the PP2A/B55α/HIF pathway and shows protective effects in a murine model of traumatic brain injuryJournal of neuroinflammationJuly 9, 2022Navarrete C, García-Martín A, Correa-Sáez A, Prados ME, Fernández F, Pineda R, Mazzone M, Álvarez-Benito M, Calzado MA, Muñoz E.

(20) Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 DiabetesFrontiers in PhysiologyJune 28, 2022Nikki L. Farnsworth, Robert A. Piscopio, Wolfgang E. Schleicher, David G. Ramirez, Jose G. Miranda, Richard K. P. Benningernecrosis factor-α (TNF-α, 410-MT-010/CF, R&D Systems, ED50 = 8–50 pg/ml), 5 ng/ml interleukin-1 β (IL-1β, 401-ML-005/CF, R&D systems, ED50 = 2–10 pg/ml), and 100 ng/ml interferon-γ (IFN-γ, 485-MI-100/CF, R&D Systems, ED50

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IL-1 beta/IL-1F2 Protein

IL-1 beta/IL-1F2 Protein

IL-1 beta/IL-1F2 Protein

IL-1 beta/IL-1F2 Protein

Recombinant Mouse IL-1 beta/IL-1F2 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse IL-1 beta/IL-1F2 Protein, CF from R&D Systems, a Bio-Techne Brand

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