CCL3/MIP-1 alpha Isoform LD78a Protein 270-LD-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCCL3/MIP-1 alpha Isoform LD78a Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $322.00Supplier Page View Company Product Page
Catalog Number270-LD-010
SpeciesHuman
Size10 ug (also 50 ug)
Source/Expression SystemE. coli-derived Recombinant Human CCL3/MIP-1 alpha Protein
Molecule NameCCL3/MIP-1 alpha
NCBI Full Gene NameC-C motif chemokine ligand 3
NCBI Gene AliasesMIP-1-alpha, MIP1A, LD78ALPHA, G0S19-1, SCYA3
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight7.5 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 50 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

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(2) Identification of CCL3 as a Schwann cell chemotactic factor essential for nerve regenerationCell reportsFebruary 25, 2025Van Emmenis L, Mòdol-Caballero G, Harford-Wright E, Power A, Cattin AL, White IJ, Casal G, Boal-Carvalho I, Bennett CL, Lloyd AC.

(3) Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in miceNature communicationsOctober 9, 2024Luo M, Almeida D, Dallacasagrande V, Hedhli N, Gupta M, D'Amico DJ, Kiss S, Hajjar KA.

(4) Chemokine-mediated cell migration into the central nervous system in progressive multifocal leukoencephalopathyCell Reports MedicineJuly 16, 2024Marie Deffner, Tilman Schneider-Hohendorf, Andreas Schulte-Mecklenbeck, Simon Falk, I-Na Lu, Patrick Ostkamp, Louisa Müller-Miny, Eva Maria Schumann, Susan Goelz, Ellen Cahir-McFarland, et al.210-TA-005 Recombinant human CCL2,R&D Systems,Cat# 279-MC-010 Recombinant human CCL3,R&D Systems,Cat# 270-LD-010 Recombinant human CCL5,R&D Systems,Cat# 278-RN-010 Recombinant human CCL20,R&D Systems,Cat# 360-MP-025 Recombinant

(5) Role of CCR3 in respiratory syncytial virus infection of airway epithelial cellsiScienceDecember 17, 2021Wellemans V, Benhassou HA, Fuselier E, Bellesort F, Dury S, Lebargy F, Dormoy V, Fichel C, Naour RL, Gounni AS, et al.

(6) A Polymorphism in C-C Chemokine Receptor 5 (CCR5) Associates with Löfgren's Syndrome and Alters Receptor Expression as well as Functional ResponseCellsAugust 3, 2021Karakaya B, van Moorsel CHM, Veltkamp M, Roodenburg-Benschop C, Kazemier KM, van der Helm-van Mil AHM, Huizinga TWJ, Grutters JC, Rijkers GT.

(7) Prevention of CaCl₂-induced aortic inflammation and subsequent aneurysm formation by the CCL3-CCR5 axisNature communicationsNovember 25, 2020Ishida Y, Kuninaka Y, Nosaka M, Kimura A, Taruya A, Furuta M, Mukaida N, Kondo T.

(8) CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathwaysLaboratory investigation; a journal of technical methods and pathologySeptember 1, 2020Kodama T, Koma YI, Arai N, Kido A, Urakawa N, Nishio M, Shigeoka M, Yokozaki H.

(9) GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet's diseaseArthritis research & therapyJune 12, 2018Nakano H, Kirino Y, Takeno M, Higashitani K, Nagai H, Yoshimi R, Yamaguchi Y, Kato I, Aoki I, Nakajima H.

(10) BTK^Cys481Ser drives ibrutinib resistance via ERK1/2 and protects BTK^wild-type MYD88-mutated cells by a paracrine mechanismBloodMay 3, 2018Chen JG, Liu X, Munshi M, Xu L, Tsakmaklis N, Demos MG, Kofides A, Guerrera ML, Chan GG, Patterson CJ, et al.

(11) Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemiaOncogeneJune 29, 2017van Attekum MHA, Terpstra S, Slinger E, von Lindern M, Moerland PD, Jongejan A, Kater AP, Eldering E.

(12) Adsorption as a Contributor for Inflammatory Mediators Removal by Different Hemofiltration Membranes: A Pilot StudyArtificial organsJune 1, 2017Malard B, Florens N, Lambert C, Juillard L.

(13) Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)The Journal of biological chemistryDecember 23, 2016Karlshøj S, Amarandi RM, Larsen O, Daugvilaite V, Steen A, Brvar M, Pui A, Frimurer TM, Ulven T, Rosenkilde MM.

(14) Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategiesMucosal immunologyNovember 1, 2016Sips M, Krykbaeva M, Diefenbach TJ, Ghebremichael M, Bowman BA, Dugast AS, Boesch AW, Streeck H, Kwon DS, Ackerman ME, et al.

(15) Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokinesEuropean journal of immunologyJanuary 1, 2015Gouwy M, De Buck M, Pörtner N, Opdenakker G, Proost P, Struyf S, Van Damme J.

(16) Increased levels of soluble interleukin-6 receptor and CCL3 in COPD sputumRespiratory researchSeptember 4, 2014Ravi AK, Khurana S, Lemon J, Plumb J, Booth G, Healy L, Catley M, Vestbo J, Singh D.

(17) Neuropeptide Y induces potent migration of human immature dendritic cells and promotes a Th2 polarizationFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJuly 1, 2014Buttari B, Profumo E, Domenici G, Tagliani A, Ippoliti F, Bonini S, Businaro R, Elenkov I, Riganò R.

(18) Lactoferrin regulates an axis involving CD11b and CD49d integrins and the chemokines MIP-1α and MCP-1 in GM-CSF-treated human primary eosinophilsJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine ResearchOctober 1, 2012Curran CS, Bertics PJ.

(19) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(20) CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual-tropic (R5/X4) HIV-1 infectionEuropean journal of immunologyApril 1, 2011Gouwy M, Struyf S, Berghmans N, Vanormelingen C, Schols D, Van Damme J.

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CCL3/MIP-1 alpha Isoform LD78a Protein

CCL3/MIP-1 alpha Isoform LD78a Protein

CCL3/MIP-1 alpha Isoform LD78a Protein

CCL3/MIP-1 alpha Isoform LD78a Protein

CCL3/MIP-1 alpha Isoform LD78a Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (43)

Reviews

CCL3/MIP-1 alpha Isoform LD78a Protein from R&D Systems, a Bio-Techne Brand

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