IL-23 Protein 1290-IL-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-23 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $459.00Supplier Page View Company Product Page
Catalog Number1290-IL-010
SpeciesHuman
Size10 ug
Molecule NameIL-23
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human IL-23 Protein
NCBI Full Gene Nameinterleukin 12B, interleukin 23 subunit alpha
NCBI Gene AliasesIL-23A, CLMF, IL-23, IL23P19, NKSF, NKSF2, CLMF2, P19, SGRF, IMD29, IMD28, IL-12B
FormatLyophilized from a 0.2 µm filtered solution in MES, NaCl and EDTA with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseasesCell GenomicsMarch 11, 2026Alok Jaiswal, Tristan Kooistra, Vladislav Pokatayev, Hélder N. Bastos, Rita F. Santos, Tresa R. Sarraf, Åsa Segerstolpe, Crystal Lin, Liat Amir-Zilberstein, Shaina Twardus, et al.PeproTech; Thermo Fisher Scientific, #200-06), IL-23α (Recombinant Human IL-23 Protein; R&D Systems, #1290-IL-010), IL-12β (Recombinant Human IL-12/IL-23 p40 Monomer Protein; R&D Systems, #309-IL-010), BMP-2 (Human/Mouse/Rat

(2) NGO ameliorates psoriasis by modulating mitochondrial function and suppressing pSTAT3–IL-17–expressing CD8+ TRM cellsJournal of NanobiotechnologyJanuary 16, 2026Tae Ho Kim, Chae Rim Lee, Kyoung Min Choi, Soon Won Choi, Seon-Yeong Lee, A. Ram Lee, Jung Won Choi, Young Mi Moon, Joonhyuck Park, Haeyoun Choi, et al.and stimulated 72 h with anti-CD3, anti-CD28, and recombinant IL-6, or recombinant IL-23 (10 ng/ml, 1290-IL-010, R&D Systems) using an XF24 Extracellular Flux Analyzer (Seahorse Bioscience, Chicopee, MA, USA). To

(3) Migration arrest and transendothelial trafficking of human pathogenic-like Th17 cells are mediated by differentially positioned chemokinesNature communicationsFebruary 26, 2025Parween F, Singh SP, Kathuria N, Zhang HH, Ashida S, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, et al.

(4) Tuberculosis in otherwise healthy adults with inherited TNF deficiencyNatureSeptember 1, 2024Arias AA, Neehus AL, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J, et al.

(5) Human inherited CCR2 deficiency underlies progressive polycystic lung diseaseCellJanuary 18, 2024Neehus AL, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, Arango-Franco CA, Philippot Q, Modaresi M, Mohammadzadeh I, et al.human Interleukin-12,R&D Systems,Cat# 219-IL-025 Recombinant human Interleukin-23,R&D Systems,Cat# 1290-IL-010 Recombinant human GM-CSF,R&D Systems,Cat# 215-GM Protamine sulfate,Merck,Cat# P3369-10G Recombinant

(6) Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor ImmunityCancer researchJanuary 2, 2024Rangel Rivera GO, Dwyer CJ, Knochelmann HM, Smith AS, Aksoy BA, Cole AC, Wyatt MM, Kumaresan S, Thaxton JE, Lesinski GB, et al.

(7) Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver diseaseEBioMedicineSeptember 1, 2023Vaikunthanathan T, Landmann E, Correa DM, Romano M, Trevelin SC, Peng Q, Crespo E, Corrado M, Lozano JJ, Pearce EL, et al.

(8) Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cellsbioRxiv : the preprint server for biologyFebruary 13, 2023Parween F, Singh SP, Zhang HH, Kathuria N, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, Lorenzi HA, et al.

(9) Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic EuropeCell GenomFebruary 8, 2023Kerner G, Neehus AL, Philippot Q, Bohlen J, Rinchai D, Kerrouche N, Puel A, Zhang SY, Boisson-Dupuis S, Abel L, et al.Human IL-2 Recombinant Protein,Gibco Thermo,Cat#PHC0023 Recombinant Human IL-23 Protein,R&D/Bio techne,Cat#1290-IL-010 LIVE/DEAD Fixable Aqua Dead Cell Stain Kit,Thermo Fisher Scientific,Cat#L34966 Intron A,Merk,N/A Lipofectamine™ 2000 Transfection Reagent

(10) IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasisNature communicationsSeptember 22, 2022Millet N, Solis NV, Aguilar D, Lionakis MS, Wheeler RT, Jendzjowsky N, Swidergall M.

(11) Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 ReceptorCellsAugust 19, 2022Rode AKO, Buus TB, Mraz V, Al-Jaberi FAH, Lopez DV, Ford SL, Hennen S, Eliasen IP, Klewe IV, Gharehdaghi L, et al.

(12) An inhibitor of RORγ for chronic pulmonary obstructive disease treatmentScientific reportsMay 24, 2022Desai H, Marathe M, Potdar V, Tiwari P, Joshi A, Kadam SR, Joshi AR, Kulkarni A, Bhosale V, Hadambar A, et al.

(13) Th17-Dependent Nasal Hyperresponsiveness Is Mitigated by Steroid TreatmentBiomoleculesMay 6, 2022Ueda S, Miura K, Kawasaki H, Ogata S, Yamasaki N, Miura S, Mori A, Kaminuma O.

(14) RORγt phosphorylation protects against T cell-mediated inflammationCell reportsMarch 15, 2022Ma S, Patel SA, Abe Y, Chen N, Patel PR, Cho BS, Abbasi N, Zeng S, Schnabl B, Chang JT, et al.

(15) A multivariate modeling framework to quantify immune checkpoint context-dependent stimulation on T cellsCell discoveryJanuary 4, 2022Karpf L, Trichot C, Faucheux L, Legbre I, Grandclaudon M, Lahoute C, Mattoo H, Pasquier B, Soumelis V.

(16) Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid ArthritisJournal of immunology researchJanuary 1, 2022Vitales-Noyola M, Hernández-Castro B, Alvarado-Hernández D, Baranda L, Bernal-Silva S, Abud-Mendoza C, Niño-Moreno P, González-Amaro R.

(17) Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human OligodendrocytesFrontiers in immunologyJanuary 1, 2022Jamann H, Cui QL, Desu HL, Pernin F, Tastet O, Halaweh A, Farzam-Kia N, Mamane VH, Ouédraogo O, Cleret-Buhot A, et al.for Th17 polarization cells were cultured with human recombinant IL-23 (25 ng/ml, R&D Systems, Cat# 1290-IL-010, Minneapolis, MN, USA) and with αIL-4 (5 μg/ml, Bio X Cell, Cat# BE0240) as previously published (12).

(18) IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritisJournal of translational medicineSeptember 16, 2021Min HK, Kim S, Lee JY, Kim KW, Lee SH, Kim HR.

(19) Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a childNature medicineSeptember 1, 2021Ogishi M, Yang R, Aytekin C, Langlais D, Bourgey M, Khan T, Ali FA, Rahman M, Delmonte OM, Chrabieh M, et al.

(20) IL-27 Mediates PD-L1 Expression and Release by Human Mesothelioma CellsCancersAugust 9, 2021Carbotti G, Dozin B, Martini S, Giordano C, Scordamaglia F, Croce M, Filaci G, Ferrini S, Fabbi M.IL-6 (206-IL-010), recombinant human IL-6R/IL-6 chimera (8954-SR-025), IL-12 (219-IL-005), and IL-23 (1290-IL-010) from R&D Systems, IFN-γ (PeproTech, 300–02), IL-35 (Enzo Life Sciences, ALX-522-140-C010), IL-30 (Abnova,

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IL-23 Protein

IL-23 Protein

IL-23 Protein

IL-23 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (123)

Reviews

IL-23 Protein from R&D Systems, a Bio-Techne Brand

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