Recombinant Human/Mouse/Rat GDF-11/BMP-11 Protein 1958-GD-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human/Mouse/Rat GDF-11/BMP-11 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $408.00Supplier Page View Company Product Page
Catalog Number1958-GD-010
SpeciesHuman, Mouse, Rat
Molecule NameGDF-11/BMP-11
Size10 ug (also 50 ug, 200 ug, 1 mg)
Source/Expression SystemE. coli-derived Recombinant Human/Mouse/Rat GDF-11/BMP-11 Protein
NCBI Full Gene Namegrowth differentiation factor 11
NCBI Gene AliasesBMP11, VHO, BMP-11
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular Weight12.6 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Tppp3 is a novel molecule for retinal ganglion cell identification and optic nerve regenerationActa neuropathologica communicationsDecember 29, 2024Rao M, Luo Z, Liu CC, Chen CY, Wang S, Nahmou M, Tanasa B, Virmani A, Byrne L, Goldberg JL, et al.

(2) Gene regulatory roles of growth and differentiation factors in retinal developmentiScienceJune 21, 2024Ziming Luo, Sahil Shah, Bogdan Tanasa, Kun-Che Chang, Jeffrey L. Goldbergand recombinant proteins","Chemicals, peptides, and recombinant proteins" ,, GDF 11,R & D systems,1958-GD-010 GDF 15,R & D systems,89-44G-D025 B27,Gibco,17504-044 Transferrin,Sigma,T-1147 BSA,Sigma,A-4161 Putrescine,Sigma,P7505 Sodium selenite

(3) GDF11 Regulates PC12 Neural Stem Cells via ALK5-Dependent PI3K-Akt Signaling PathwayInternational journal of molecular sciencesOctober 14, 2022Wang Z, Jiang P, Liu F, Du X, Ma L, Ye S, Cao H, Sun P, Su N, Lin F, et al.

(4) Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertensionSkeletal muscleMay 6, 2022Xiang G, Ying K, Jiang P, Jia M, Sun Y, Li S, Wu X, Hao S.

(5) Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagyAging cellJanuary 1, 2022Sun J, Li Y, Yang X, Dong W, Yang J, Hu Q, Zhang C, Fang H, Liu A.

(6) GDF11 alleviates secondary brain injury after intracerebral hemorrhage via attenuating mitochondrial dynamic abnormality and dysfunctionScientific reportsFebruary 17, 2021Xiao A, Zhang Y, Ren Y, Chen R, Li T, You C, Gan X.buffer for intraperitoneal (IP) injections. IP injections of recombinant GDF11 (R&D Systems, catalog No.1958-GD-010) (0.1 mg/kg/day) or vehicle only (30 mM acetate) were first given 2 h prior to operation and daily continued

(7) RAP-011 Rescues the Disease Phenotype in a Cellular Model of Congenital Dyserythropoietic Anemia Type II by Inhibiting the SMAD2-3 PathwayInternational journal of molecular sciencesAugust 4, 2020De Rosa G, Andolfo I, Marra R, Manna F, Rosato BE, Iolascon A, Russo R.

(8) TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle MassFrontiers in physiologyJanuary 1, 2020Hagg A, Kharoud S, Goodchild G, Goodman CA, Chen JL, Thomson RE, Qian H, Gregorevic P, Harrison CA, Walton KL.

(9) A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx miceSkeletal muscleMay 27, 2019Jin Q, Qiao C, Li J, Xiao B, Li J, Xiao X.Tris, 0.15 M NaCl, 0.001 M EDTA, 1% NP-40, 5%, glycerol, pH 7.4). To assess complex formation, rGDF11 (1958-GD-010; R&D Systems; Minneapolis, MN), recombinant MSTN (rMSTN; 788-G8–010; R&D Systems; Minneapolis, MN) or

(10) Growth differentiation factor 11 is involved in isoproterenol‑induced heart failureMolecular medicine reportsMay 1, 2019Zhang XJ, Tan H, Shi ZF, Li N, Jia Y, Hao Z.

(11) Identification of the minimum region of flatfish myostatin propeptide (Pep45-65) for myostatin inhibition and its potential to enhance muscle growth and performance in animalsPloS oneJanuary 1, 2019Kim JH, Kim JH, Sutikno LA, Lee SB, Jin DH, Hong YK, Kim YS, Jin HJ.

(12) Growth differentiation factor 11 (GDF11) has pronounced effects on skin biologyPloS oneJanuary 1, 2019Idkowiak-Baldys J, Santhanam U, Buchanan SM, Pfaff KL, Rubin LL, Lyga J.

(13) Reduced production of laminin by hepatic stellate cells contributes to impairment in oval cell response to liver injury in aged miceAgingDecember 4, 2018Qian L, Zhang H, Gu Y, Li D, He S, Wang H, Cheng Y, Yang W, Yu H, Zhao X, et al.1324-WN-010), TGF-β1 (R&D Systems, Minneapolis, USA, 7666-MB-005) and GDF11(R&D Systems, Minneapolis, USA, 1958-GD-010). Co-culture of OCs with HSCs and BrdU analysis Primary HSCs were isolated from naive GFP transgenic

(14) Conditioned media from human umbilical cord blood-derived mesenchymal stem cells stimulate rejuvenation function in human skinBiochemistry and biophysics reportsDecember 1, 2018Kim YJ, Seo DH, Lee SH, Lee SH, An GH, Ahn HJ, Kwon D, Seo KW, Kang KS.

(15) GDF11 induces differentiation and apoptosis and inhibits migration of C17.2 neural stem cells via modulating MAPK signaling pathwayPeerJSeptember 4, 2018Zongkui Wang, Miaomiao Dou, Fengjuan Liu, Peng Jiang, Shengliang Ye, Li Ma, Haijun Cao, Xi Du, Pan Sun, Na Su, et al.Biological Industries (Beit Haemek, Israel). Recombinant human/mouse/rat GDF-11/BMP-11 (catalog No. 1958-GD-010) and Phospho-MAPK proteome profiler array kit (catalog No. ARY002B) were obtained from R&D systems (Minneapolis,

(16) Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technologyBiochemistry and biophysics reportsSeptember 1, 2017Sakamoto K, Kanematsu-Yamaki Y, Kamada Y, Oka M, Ohnishi T, Miwa M, Asami T, Inooka H.

(17) Modulation of GDF11 expression and synaptic plasticity by age and trainingOncotargetAugust 29, 2017De Domenico E, D'Arcangelo G, Faraoni I, Palmieri M, Tancredi V, Graziani G, Grimaldi P, Tentori L.

(18) A multiplexed immunocapture liquid chromatography tandem mass spectrometry assay for the simultaneous measurement of myostatin and GDF-11 in rat serum using an automated sample preparation platformAnalytica chimica actaAugust 1, 2017Zhao Y, Liu G, Zambito FC, Zhang YJ, DeSilva BS, Kozhich AT, Shen JX.

(19) Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and diseaseProceedings of the National Academy of Sciences of the United States of AmericaJune 27, 2017Chen JL, Walton KL, Hagg A, Colgan TD, Johnson K, Qian H, Gregorevic P, Harrison CA.

(20) Curcumin alleviates lumbar radiculopathy by reducing neuroinflammation, oxidative stress and nociceptive factorsEuropean cells & materialsMay 9, 2017Xiao L, Ding M, Fernandez A, Zhao P, Jin L, Li X.

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Recombinant Human/Mouse/Rat GDF-11/BMP-11 Protein

GDF-11/BMP-11 Protein

GDF-11/BMP-11 Protein

GDF-11/BMP-11 Protein

GDF-11/BMP-11 Protein

Recombinant Human/Mouse/Rat GDF-11/BMP-11 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human/Mouse/Rat GDF-11/BMP-11 Protein from R&D Systems, a Bio-Techne Brand

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