Recombinant Human ACE-2 Protein, CF 933-ZN-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human ACE-2 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $445.00Supplier Page View Company Product Page
Catalog Number933-ZN-010
SpeciesHuman
FormatSupplied as a 0.2 µm filtered solution in Tris, NaCl, ZnCl2 and Glycerol
Molecule NameACE-2
Size10 ug (also 100 ug)
NCBI Full Gene Nameangiotensin converting enzyme 2
NCBI Gene AliasesACEH
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 101-111 kDa, reducing conditions
Theoretical: 85 kDa
ApplicationsEnzyme Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human ACE-2 Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Aminopeptidase A Effect on Angiotensin Peptides and Their Blood Pressure ActionInternational journal of molecular sciencesJuly 21, 2025Forster P, Wysocki J, Abedini Y, Müller T, Ye M, Ferrario CM, Batlle D.

(2) Genetically edited human placental organoids cast new light on the role of ACE2Cell death & diseaseFebruary 7, 2025Arthurs AL, Dietrich B, Knöfler M, Lushington CJ, Thomas PQ, Adikusuma F, Williamson JM, Babikha S, Damhuis T, Jankovic-Karasoulos T, et al.

(3) SARS-CoV-2 spike does not interact with the T cell receptor or directly activate T cellsProceedings of the National Academy of Sciences of the United States of AmericaJuly 30, 2024Gaglione SA, Rosales TJ, Schmidt-Hong L, Baker BM, Birnbaum ME.

(4) Absolute concentration estimation of COVID-19 convalescent and post-vaccination IgG antibodiesPloS oneJanuary 1, 2024Klegerman ME, Peng T, Seferovich I, Rahbar MH, Hessabi M, Tahanan A, Wanger A, Grimes CZ, Ostrosky-Zeichner LZ, Koster K, et al.

(5) Existence of Quantum Pharmacology in Sartans: Evidence in Isolated Rabbit Iliac ArteriesInt J Mol SciDecember 16, 2023Laura Kate Gadanec, Jordan Swiderski, Vasso Apostolopoulos, Kostantinos Kelaidonis, Veroniki P. Vidali, Aleksander Canko, Graham J. Moore, John M. Matsoukas, Anthony Zullisequence ARVYIHPF (Cat# 100365) were purchased from Mimitopes (Mulgrave, VIC, Australia); rhACE2 (Cat#933-ZN-010) was purchased from R&D systems (Minneapolis, MN, USA); telmisartan (Cat#S1738) was purchased from Selleck Chemicals

(6) SARS-CoV-2 Spike Proteins and Cell-Cell Communication Induce P-Selectin and Markers of Endothelial Injury, NETosis, and Inflammation in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for the Pathogenesis of COVID-19 CoagulopathyInternational journal of molecular sciencesAugust 9, 2023Bhargavan B, Kanmogne GD.

(7) Molecular Mechanisms of Endothelialitis in SARS-CoV-2 Infection: Evidence for VE-Cadherin Cleavage by ACE2International journal of molecular sciencesAugust 7, 2023Bouillet L, Deroux A, Benmarce M, Guérin C, Bouvet L, Garnier O, Martin DK, Vilgrain I.

(8) A Prototype Assay Multiplexing SARS-CoV-2 3CL-Protease and Angiotensin-Converting Enzyme 2 for Saliva-Based Diagnostics in COVID-19BiosensorsJune 27, 2023Suresh V, Sheik DA, Detomasi TC, Zhao T, Zepeda T, Saladi S, Rajesh UC, Byers K, Craik CS, Davisson VJ.

(9) Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced inflammationInternational immunopharmacologyApril 1, 2023Fu L, Gilham D, Stotz SC, Sarsons CD, Rakai BD, Tsujikawa LM, Wasiak S, Johansson JO, Sweeney M, Wong NCW, et al.

(10) Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2Nature communicationsDecember 23, 2022Guo X, Cao J, Cai JP, Wu J, Huang J, Asthana P, Wong SKK, Ye ZW, Gurung S, Zhang Y, et al.

(11) Development and Characterization of Phage-Display-Derived Novel Human Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2BiomedicinesDecember 17, 2022Kim JW, Min SW, Lee J, Shin HG, Choi HL, Yang HR, Lee JH, Cho YB, Shim H, Lee S.

(12) The systemic renin-angiotensin system in COVID-19Scientific reportsNovember 22, 2022Reindl-Schwaighofer R, Hödlmoser S, Domenig O, Krenn K, Eskandary F, Krenn S, Schörgenhofer C, Rumpf B, Karolyi M, Traugott MT, et al.

(13) SARS-CoV-2 Spike Proteins and Cell-Cell Communication Inhibits TFPI and Induces Thrombogenic Factors in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for COVID-19 Coagulopathy PathogenesisInternational journal of molecular sciencesSeptember 9, 2022Bhargavan B, Kanmogne GD.Reagents Recombinant SARS-CoV-2 S-proteins, SW (cat. #10549-CV-100), SD (cat. #10878-CV-100), rhACE2 (cat. #933-ZN-010), rTFPI (cat. #2974-PI-010), and TM (BDCA3, cat. #3947-PA-010) were purchased from R&D Systems (Minneapolis,

(14) Decrease in Angiotensin-Converting Enzyme activity but not concentration in plasma/lungs in COVID-19 patients offers clues for diagnosis/treatmentMolecular therapy. Methods & clinical developmentSeptember 8, 2022Daniell H, Nair SK, Shi Y, Wang P, Montone KT, Shaw PA, Choi GH, Ghani D, Weaver J, Rader DJ, et al.

(15) Molecular Interactions of Tannic Acid with Proteins Associated with SARS-CoV-2 InfectivityInternational journal of molecular sciencesFebruary 27, 2022Haddad M, Gaudreault R, Sasseville G, Nguyen PT, Wiebe H, Van De Ven T, Bourgault S, Mousseau N, Ramassamy C.

(16) Immune Dysregulation in Acute SARS-CoV-2 InfectionPathogens & immunityJanuary 1, 2022Grimm L, Onyeukwu C, Kenny G, Parent DM, Fu J, Dhingra S, Yang E, Moy J, Utz PJ, Tracy R, et al.calibrator used for this assay is R&D Systems Recombinant ACE2 Protein, carrier free (Catalog Number 933-ZN-010). After undergoing a wash cycle, the beads and captured analyte are incubated with biotinylated detection

(17) ACE2-cytomimetic particles restrict SARS-Cov-2 spike protein binding to cellular targetsBiotechnology ReportsDecember 1, 2021Thomas A. Strong, Daniel Pelaez88,832) were functionalized with an excess molar amount of recombinant human ACE2 (R&D Systems, Cat# 933-ZN-010), by overnight incubation under constant rotation in binding buffer to generate rhACE2-cytomimetic particles.

(18) ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injuryNature communicationsNovember 23, 2021Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, et al.

(19) Molecular Masks for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus EntryInternational journal of molecular sciencesAugust 20, 2021Shukla SP, Cho KB, Rustagi V, Gao X, Fu X, Zhang SX, Guo B, Udugamasooriya DG.S14–S16). 4.15. In Vitro Pull-Down Assay 10 nM of recombinant human ACE2 protein (R&D system, Cat# 933-ZN-010, Minneapolis, MN, USA) was incubated with ACE2P1 and ACE2P2 conjugated beads in RIPA buffer at 4 °C

(20) Discovery of Small Anti-ACE2 Peptides to Inhibit SARS-CoV-2 InfectivityAdvanced therapeuticsJuly 1, 2021Adhikary P, Kandel S, Mamani UF, Mustafa B, Hao S, Qiu J, Fetse J, Liu Y, Ibrahim NM, Li Y, et al.before.[ 19 ] Two wells in a plate were coated with recombinant human ACE2 protein (200 ng) (catalog# 933‐ZN‐010, R&D Systems, Minneapolis, MN) overnight at 4 ℃ with gentle shaking. The first well was blocked with

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ACE-2 Protein

ACE-2 Protein

ACE-2 Protein

ACE-2 Protein

ACE-2 Protein

Recombinant Human ACE-2 Protein, CF from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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Recombinant Human ACE-2 Protein, CF from R&D Systems, a Bio-Techne Brand

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