Recombinant Mouse P-Selectin/CD62P Fc Chimera Protein, CF 737-PS-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse P-Selectin/CD62P Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $315.00Supplier Page View Company Product Page
Catalog Number737-PS-050
SpeciesMouse
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameP-Selectin/CD62P
Size50 ug (also 200 ug)
NCBI Full Gene Nameselectin, platelet
NCBI Gene AliasesPADGEM, Grmp, GMP-140, CD62P, LECAM3
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 127-140 kDa, reducing conditions
Theoretical: 99.1 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse P-Selectin/CD62P Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Targeted Delivery to Dying Cells Through P-Selectin-PSGL-1 Axis: A Promising Strategy for Enhanced Drug Efficacy in Liver Injury ModelsCellsOctober 27, 2024Lien TS, Sun DS, Chang HH.

(2) Dual phenotypic characteristics of P-selectin in a mouse model of hemorrhagic shock and hepatectomyHeliyonAugust 1, 2023Chen JL, Cheng TT, Huang CC, Chang HH, Lam CF.

(3) T helper 1 effector memory CD4(+) T cells protect the skin from poxvirus infectionCell reportsMay 30, 2023Harbour JC, Abdelbary M, Schell JB, Fancher SP, McLean JJ, Nappi TJ, Liu S, Nice TJ, Xia Z, Früh K, et al.119507Uniprot ID: P04233 "Recombinant Mouse P-Selectin/CD62P Fc Chimera Protein, CF",R & D Systems,Cat#737-PS-050 "Recombinant Mouse E-Selectin/CD62E Fc Chimera Protein, CF",R & D Systems,Cat#575-ES-100 eBioscience

(4) Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8(+) T cells with enhanced tumor homing to improve cell therapyCell reportsMarch 28, 2023Camargo CP, Muhuri AK, Alapan Y, Sestito LF, Khosla M, Manspeaker MP, Smith AS, Paulos CM, Thomas SN.

(5) A humanized β(2) integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivoCell reportsMay 31, 2022Wen L, Marki A, Wang Z, Orecchioni M, Makings J, Billitti M, Wang E, Suthahar SSA, Kim K, Kiosses WB, et al.720-IC-050 Recombinant human IL-8,R&D Systems,Cat# 208-IL-010 Recombinant mouse P-selectin-Fc,R&D Systems,Cat# 737-PS-050 Recombinant mouse ICAM-1-Fc,R&D Systems,Cat# 796-IC-050 Recombinant Mouse CXCL1/KC Protein,R&D Systems,Cat#453-KC-010 Casein

(6) Endothelial STING controls T cell transmigration in an IFNI-dependent mannerJCI insightAugust 9, 2021Anastasiou M, Newton GA, Kaur K, Carrillo-Salinas FJ, Smolgovsky SA, Bayer AL, Ilyukha V, Sharma S, Poltorak A, Luscinskas FW, et al.from Thermo Fisher Scientific. Recombinant mouse E-selectin (catalog 575-ES-100), P-selectin (catalog 737-PS-050), ICAM1 (catalog 796-IC-050), VCAM1 Fc-chimeras (catalog 643-VM-050), and mouse CXCL10/IP-10/CRG-2 antibody

(7) Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2Cell reportsDecember 22, 2020Florez MA, Matatall KA, Jeong Y, Ortinau L, Shafer PW, Lynch AM, Jaksik R, Kimmel M, Park D, King KY.

(8) Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistanceNature communicationsApril 27, 2020Barbier V, Erbani J, Fiveash C, Davies JM, Tay J, Tallack MR, Lowe J, Magnani JL, Pattabiraman DR, Perkins AC, et al.

(9) Targeted Expansion of Tissue-Resident CD8⁺ T Cells to Boost Cellular Immunity in the SkinCell reportsDecember 3, 2019Hobbs SJ, Nolz JC.

(10) Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymuseLifeSeptember 6, 2018Moretti FA, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, Scheiermann C, Sperandio M, Fässler R, Moser M.

(11) Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolismNatureMarch 9, 2017Pan Y, Tian T, Park CO, Lofftus SY, Mei S, Liu X, Luo C, O'Malley JT, Gehad A, Teague JE, et al.

(12) Dermal γδ T Cells Do Not Freely Re-Circulate Out of Skin and Produce IL-17 to Promote Neutrophil Infiltration during Primary Contact HypersensitivityPloS oneJanuary 1, 2017Jiang X, Park CO, Geddes Sweeney J, Yoo MJ, Gaide O, Kupper TS.

(13) Sepsis-Induced Thymic Atrophy Is Associated with Defects in Early LymphopoiesisStem CellsDecember 1, 2016Kong Y, Li Y, Zhang W, Yuan S, Winkler R, Kröhnert U, Han J, Lin T, Zhou Y, Miao P, et al.

(14) Platelets Guide Leukocytes to Their Sites of ExtravasationPLoS biologyMay 1, 2016Zuchtriegel G, Uhl B, Puhr-Westerheide D, Pörnbacher M, Lauber K, Krombach F, Reichel CA.

(15) CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In VivoJournal of immunology (Baltimore, Md. : 1950)February 1, 2016Velázquez F, Grodecki-Pena A, Knapp A, Salvador AM, Nevers T, Croce K, Alcaide P.

(16) Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectinNature communicationsApril 2, 2015Nussbaum C, Bannenberg S, Keul P, Gräler MH, Gonçalves-de-Albuquerque CF, Korhonen H, von Wnuck Lipinski K, Heusch G, de Castro Faria Neto HC, Rohwedder I, et al.

(17) Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivoNature communicationsMarch 31, 2015Krishnamurthy VR, Sardar MY, Ying Y, Song X, Haller C, Dai E, Wang X, Hanjaya-Putra D, Sun L, Morikis V, et al.

(18) Endothelial cell-derived chemerin promotes dendritic cell transmigrationJournal of immunology (Baltimore, Md. : 1950)March 1, 2014Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S.

(19) Raised soluble P-selectin moderately accelerates atherosclerotic plaque progressionPloS oneJanuary 1, 2014Woollard KJ, Lumsden NG, Andrews KL, Aprico A, Harris E, Irvine JC, Jefferis AM, Fang L, Kanellakis P, Bobik A, et al.

(20) Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assaysBloodOctober 4, 2012Sackmann EK, Berthier E, Young EW, Shelef MA, Wernimont SA, Huttenlocher A, Beebe DJ.capture Prior to the blood draw, microchannels were coated with 100 µg/mL concentration P-selectin (737PS-050; R&D Systems, McKinley Place, Minneapolis, MN) for at least 30 minutes at 4°C. Mice were anesthetized

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Recombinant Mouse P-Selectin/CD62P Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse P-Selectin/CD62P Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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