FGF-8 b Isoform Protein 423-F8-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFGF-8 b Isoform Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $334.00Supplier Page View Company Product Page
Catalog Number423-F8-025/CF
Molecule NameFGF-8
FormatLyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4 and Brij-35
Size25 ug
NCBI Full Gene Namefibroblast growth factor 8
NCBI Gene AliasesHH6, AIGF, FGF-8, HBGF-8, Fgf6c, KAL6, Aigf, Fgf-8
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human/Mouse FGF-8b Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, 2 to 8 °C under sterile conditions after reconstitution
SpeciesHuman, Mouse

Specifications/Features

Available conjugates: Sizes Available: 25 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson’s diseaseiScienceFebruary 20, 2026Jessica Jiaxin Xie, Matas Vitkauskas, Quyen Do, Tzuen Yih Saw, Alfred Xuyang Sun, Lin Yang, Tuck Wah Soong, Kah-Leong Lim, Eng-King Tan, Huck-Hui Ng, et al.thiazovivin,Tocris,3845 Heparin,Sigma-Aldrich,9041-08-1 SB431542,Stemgent,04–0010 Noggin,ProSpec,CYT-475 CHIR99021,Reagents Direct,27-H76 SHH-C25II,R&D Systems,464-SH-025/CF FGF8,R&D Systems,423-F8-025/CF GDNF,Peprotech,450–10 Matrigel©,Sigma-Aldrich,354277 insulin,Sigma-Aldrich,11061-68-0 laminin,Sigma-Aldrich,L4544 purmophormine,Stemgent,04–0009 BDNF,Peprotech,450–02 ascorbic

(2) Fibroblast Growth Factor 8 Suppresses Neurotoxic Astrocytes and Alleviates Neuropathic Pain via Spinal FGFR3 SignalingNeuroscience BulletinOctober 30, 2025Huizhu Liu, Lanxing Yi, Guiling Li, Kangli Wang, Hongsheng Wang, Yuqiu Zhang, Benlong Liustudy [32]. Drug Administration Recombinant FGF8 protein (0.5 μg or 1 μg in 5 μL PBS; R&D Systems, 423-F8-025/CF) was administered via intrathecal (i.t.) lumbar puncture between L5–L6 vertebrae under isoflurane anesthesia

(3) A Hybrid 2D/3D Approach for Neural Differentiation Into Telencephalic Organoids and Efficient Modulation of FGF8 SignalingBIO-PROTOCOLJune 20, 2025Bertacchi Bertacchi, Gwendoline Gwendoline, Michèle Michèlefor up to 6 months) 26. Recombinant human/mouse FGF-8b protein (FGF8) (R&D Systems, catalog number: 423-F8-025/CF; prepare a 25 ng/μL stock solution by resuspending in 1× PBS supplemented with 0.1% BSA; store aliquots

(4) A Hybrid 2D/3D Approach for Neural Differentiation Into Telencephalic Organoids and Efficient Modulation of FGF8 SignalingBio ProtocJune 20, 2025Michele Bertacchi, Gwendoline Maharaux, Michèle Studerfor up to 6 months) 26. Recombinant human/mouse FGF-8b protein (FGF8) (R&D Systems, catalog number: 423-F8-025/CF; prepare a 25 ng/μL stock solution by resuspending in 1× PBS supplemented with 0.1% BSA; store aliquots

(5) Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson’s diseaseStem CellsMarch 12, 2025Amalie Holm Nygaard, Alrik L Schörling, Zehra Abay-Nørgaard, Erno Hänninen, Yuan Li, Adrian Ramón Santonja, Gaurav Singh Rathore, Alison Salvador, Charlotte Rusimbi, Katrine Bech Lauritzen, et al.Nolbrant et al protocol.6 Adaptation to the current protocol was the addition of either FGF8b (100 ng/mL, #423-F8-025/CF), FGF18 (100 ng/mL, #8988-F18-050) or FGF17b (100 ng/mL, #319-FG-025) to test for optimal VM DA patterning.

(6) Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomerseLifeJanuary 10, 2023Wu S, Hernandez Villegas NC, Sirkis DW, Thomas-Wright I, Wade-Martins R, Schekman R.

(7) A reference human induced pluripotent stem cell line for large-scale collaborative studiesCell stem cellDecember 1, 2022Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, et al.

(8) Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-proteinCell reportsOctober 25, 2022Park JS, Choi J, Cao L, Mohanty J, Suzuki Y, Park A, Baker D, Schlessinger J, Lee S.

(9) Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive stateScientific reportsOctober 17, 2022Ozaki H, Suga H, Sakakibara M, Soen M, Miyake N, Miwata T, Taga S, Nagai T, Kano M, Mitsumoto K, et al.

(10) Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomesCellSeptember 29, 2022Alessa R. Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert SchÃ¶pflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, et al.Diagnostics,1000144 Puromycin,SIGMA-ALDRICH,P8833 Recombinant Human/Mouse FGF-8b Isoform,R&D Systems,#423-F8-025/CF Recombinant Mouse Wnt-3a protein,R&D Systems,#1324-WN-010/CF "Ribonuclease A from bovine pancreas,

(11) Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer ProgressionCancersJanuary 7, 2022Yu L, Toriseva M, Afshan S, Cangiano M, Fey V, Erickson A, Seikkula H, Alanen K, Taimen P, Ettala O, et al.

(12) Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem CellsStem cells internationalJanuary 1, 2022Lee DS, Song YJ, Gug HR, Lee JH, Bae HS, Park JC.

(13) Induction of γδT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cellsJournal of cellular and molecular medicineNovember 1, 2021Hosaka N, Kanda S, Shimono T, Nishiyama T.

(14) 3D Bioprinting Mesenchymal Stem Cell-Derived Neural Tissues Using a Fibrin-Based BioinkBiomoleculesAugust 21, 2021Restan Perez M, Sharma R, Masri NZ, Willerth SM.

(15) Control of mesenchymal cell fate via application of FGF-8b in vitroStem cell researchMarch 1, 2021Otsuka T, Mengsteab PY, Laurencin CT.

(16) FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complexJournal of cellular and molecular medicineMarch 1, 2021Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W.

(17) Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational UseCell stem cellFebruary 4, 2021Kim TW, Piao J, Koo SY, Kriks S, Chung SY, Betel D, Socci ND, Choi SJ, Zabierowski S, Dubose BN, et al.

(18) Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutationsEMBO molecular medicineOctober 7, 2020Liang KX, Kristiansen CK, Mostafavi S, Vatne GH, Zantingh GA, Kianian A, Tzoulis C, Høyland LE, Ziegler M, Perez RM, et al.

(19) Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson's diseaseStem cell research & therapyAugust 8, 2020Goggi JL, Qiu L, Liao MC, Khanapur S, Jiang L, Boominathan R, Hartimath SV, Cheng P, Yong FF, Soh V, et al.

(20) Combined Dendritic and Axonal Deterioration Are Responsible for Motoneuronopathy in Patient-Derived Neuronal Cell Models of Chorea-AcanthocytosisInternational journal of molecular sciencesMarch 5, 2020Glaß H, Neumann P, Pal A, Reinhardt P, Storch A, Sterneckert J, Hermann A.

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Recombinant Human/Mouse FGF-8b Protein, CF

FGF-8 b Isoform Protein

FGF-8 b Isoform Protein

FGF-8 b Isoform Protein

FGF-8 b Isoform Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (65)

Reviews

FGF-8 b Isoform Protein from R&D Systems, a Bio-Techne Brand

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