Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein 396-HB-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNeuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $415.00Supplier Page View Company Product Page
Catalog Number396-HB-050/CF
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Size50 ug (also 200 ug, 1 mg)
Molecule NameNeuregulin-1 beta 1/NRG1 beta 1
NCBI Full Gene Nameneuregulin 1
NCBI Gene AliasesGGF2, SMDF, ARIA, NRG1-IT2, HRGA, MST131, HGL, GGF, MSTP131, HRG, NDF, HRG1
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human NRG1-beta 1/HRG1-beta 1 EGF Domain, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 50 ug (also 200 ug, 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Sequential changes in calcium transients during M phase regulate cardiomyocyte proliferationJ Cell BiolAugust 3, 2026Honghai Liu, Niyatie Ammanamanchi, Jocelyn D. Mich-Basso, Brian K. Panama, Yao Li, Winston Huang, Dena Almeida, Christopher M. Lewarchik, Brendan Lo, Yijen Wu, et al.then maintained in medium containing 100 ng/mL recombinant human neuregulin (rNRG1; R&D Systems, Cat#396-HB-050/CF) for 4 days, with medium changes every 2 days, prior to experimental use. Human fetal primary cardiomyocytes

(2) Growth factors maintain intratumoral heterogeneity and drive therapeutic resistance in triple-negative breast cancerCell reportsJanuary 27, 2026Devlin KL, Smith R, Bucher E, Dane M, Bowman CL, Carlson EJ, Kilburn D, Sudar D, Feiler HS, Heiser LM, et al.DAPI FluoroPure grade,ThermoFisher,Cat#D21490 Trypsin .25%,ThermoFisher,Cat#25200056 Recombinant human NRG1-β EGF domain,R&D Systems,Cat#396-HB-050/CF Recombinant human HGF,R&D Systems,Cat#294-HG-005/CF *All other MEMA protein information available

(3) Efficacy of Nerve-Derived Hydrogels to Promote Axon Regeneration Is Influenced by the Method of Tissue DecellularizationInternational journal of molecular sciencesAugust 6, 2022Kuna VK, Lundgren A, Anerillas LO, Kelk P, Brohlin M, Wiberg M, Kingham PJ, Novikova LN, Andersson G, Novikov LN.

(4) Neuregulin-1/ErbB4 signaling modulates Plasmodium falciparum HRP2-induced damage to brain cortical organoidsiScienceJune 17, 2022Harbuzariu A, Nti A, Harp KO, Cespedes JC, Driss A, Stiles JK.HRP2,Bio-Rad,Cat #PIP001 "Human NRG1-beta 1/HRG1-beta 1 EGF Domain Protein, Carrier Free",R&D Systems,Cat #396-HB-050/CF L-histidine,Sigma,H6034 Poly L-histidine,Sigma,P9386 Y-27632,Stem Cell Technologies,"Cat #72304,

(5) Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancerCell death & diseaseMay 9, 2022Madera S, Izzo F, Chervo MF, Dupont A, Chiauzzi VA, Bruni S, Petrillo E, Merin SS, De Martino M, Montero D, et al.

(6) Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasisCell reportsApril 5, 2022Han H, Wang Y, Curto J, Gurrapu S, Laudato S, Rumandla A, Chakraborty G, Wang X, Chen H, Jiang Y, et al.

(7) Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanismNature medicineApril 1, 2022Monteiro C, Miarka L, Perea-García M, Priego N, García-Gómez P, Álvaro-Espinosa L, de Pablos-Aragoneses A, Yebra N, Retana D, Baena P, et al.

(8) P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosiseLifeMarch 21, 2022Patritti Cram J, Wu J, Coover RA, Rizvi TA, Chaney KE, Ravindran R, Cancelas JA, Spinner RJ, Ratner N.

(9) A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasisEMBO molecular medicineMarch 7, 2022Zhu L, Retana D, García-Gómez P, Álvaro-Espinosa L, Priego N, Masmudi-Martín M, Yebra N, Miarka L, Hernández-Encinas E, Blanco-Aparicio C, et al.

(10) Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve InjuryFrontiers in cellular neuroscienceJanuary 1, 2022Ulrichsen M, Gonçalves NP, Mohseni S, Hjæresen S, Lisle TL, Molgaard S, Madsen NK, Andersen OM, Svenningsen ÅF, Glerup S, et al.

(11) Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor CellsJournal of Visualized ExperimentsSeptember 13, 2021Jody Fromm Longo, Stephanie N. Brosius, Steven L. Carrollmatrix",Corning,354230, NRG1-beta,In house,"Generated by SLC, also commercially available from R & D Systems(396-HB-050/CF).", Nuclear Stain Hoeschst 33342,Thermo,62249, Panther Gene Ontology Classification System,Panther,http://pantherdb.org,functional

(12) SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagyCell death & diseaseJuly 5, 2021Ma C, Zhang W, Wang W, Shen J, Cai K, Liu M, Cao M.

(13) Umbilical artery tissue contains p75 neurotrophin receptor-positive pericyte-like cells that possess neurosphere formation capacity and neurogenic differentiation potentialRegenerative therapyMarch 1, 2021Fujii-Tezuka R, Ishige-Wada M, Nagoshi N, Okano H, Mugishima H, Takahashi S, Morioka I, Matsumoto T.

(14) Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortexNature communicationsFebruary 8, 2021Zheng X, Salinas KJ, Velez DXF, Nakayama T, Lin X, Banerjee D, Xu X, Gandhi SP.

(15) Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's DiseaseInternational journal of molecular sciencesJanuary 12, 2021Seo HJ, Park JE, Choi SM, Kim T, Cho SH, Lee KH, Song WK, Song J, Jeong HS, Kim DH, et al.

(16) Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's DiseaseInternational journal of molecular sciencesJanuary 12, 2021Seo HJ, Park JE, Choi SM, Kim T, Cho SH, Lee KH, Song WK, Song J, Jeong HS, Kim DH, et al.

(17) ERBB3-dependent AKT and ERK pathways are essential for atrioventricular cushion development in mouse embryosPloS oneJanuary 1, 2021Kim K, Lee D.

(18) A Bioengineered Neuregulin-Hydrogel Therapy Reduces Scar Size and Enhances Post-Infarct Ventricular Contractility in an Ovine Large Animal ModelJournal of cardiovascular development and diseaseNovember 17, 2020Cohen JE, Goldstone AB, Wang H, Purcell BP, Shudo Y, MacArthur JW, Steele AN, Paulsen MJ, Edwards BB, Aribeana CN, et al.

(19) Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neuronsNature communicationsAugust 21, 2020Mazzara PG, Muggeo S, Luoni M, Massimino L, Zaghi M, Valverde PT, Brusco S, Marzi MJ, Palma C, Colasante G, et al.

(20) CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repairNature communicationsAugust 17, 2020Wang J, Wang J, Yang L, Zhao C, Wu LN, Xu L, Zhang F, Weng Q, Wegner M, Lu QR.

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Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein from R&D Systems, a Bio-Techne Brand

Description

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (77)

Reviews

Neuregulin-1 beta 1/NRG1 beta 1 EGF Domain Protein from R&D Systems, a Bio-Techne Brand

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