Recombinant Human/Mouse/Rat BMP-2 Protein 355-BM-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human/Mouse/Rat BMP-2 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $459.00Supplier Page View Company Product Page
Catalog Number355-BM-010
SpeciesHuman, Mouse, Rat
Source/Expression SystemCHO-derived Recombinant Human/Mouse/Rat BMP-2 Protein
Molecule NameBMP-2
Size10 ug (also 50 ug, 100 ug)
NCBI Full Gene Namebone morphogenetic protein 2
NCBI Gene AliasesSSFSC1, BDA2, SSFSC, BMP2A
FormatLyophilized from a 0.2 µm filtered solution in Glycine, Sucrose, Tween® 80 and Glutamic Acid with BSA as a carrier protein
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 15-16 kDa, reducing conditions
Theoretical: 13 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Cyclophilin D, Regulator of Mitochondrial Permeability Transition and Bioenergetics, Promotes Adipogenic Differentiation of Mesenchymal Stem CellsCellsMarch 13, 2026Chen Yu, Sarah E. Catheline, Roman A. Eliseevlow-glucose DMEM supplemented with 50 ng/mL of mouse recombinant BMP-2 (R&D systems, Minneapolis, MN, USA, 355-BM-010) and subcutaneously implanted into the backs of immunocompromised nude mice. Bone formation was assessed

(2) BMP2-induced Adam12 + Fibroblasts Dictate Wound-associated Skin Scarring and FibrosisInternational Journal of Biological SciencesFebruary 4, 2026Jun-Yi Chen, Jin-Ru Song, Ke-Ai Li, Xue-Yan Xu, Ding-Heng Zhu, Lian Zhang, Zi-Shuo Chen, Qing Cheng, Liu-Yi Yao, Yi-Qi Shen, et al.20μg/mL periostin (2955-F2-050, R&D Systems), 400μg/mL LDN-193189 2HCl (7507, Selleck) and 0.5μg/mL BMP2 (355-BM-010, R&D Systems) injection were described in the main text or figure legends. Harvesting dermal fibroblasts Mice

(3) A variant form of receptor activator of nuclear factor-κB functions as an osteoprotegerin mimic in bone and cardiac developmentScientific reportsJuly 31, 2025Kitazawa R, Haraguchi R, Kitazawa S.

(4) Rapidly Polymerizing Click Hydrogel Provides Localized Delivery of rhBMP2 to Promote Bone FormationPharmacol Res PerspectJune 8, 2025D. Joshua Cohen, Thomas W. Jacobs, D. Scott Wilson, Michael C. Mancini, Christine Van Duyn, Zvi Schwartz, Barbara D. Boyanpostsurgery, animals were euthanized. For this study, we used recombinant human/mouse/rat BMP2 (R&D Systems 355‐BM‐010). 10 μg BMP2 was reconstituted with 106.6 μL of crosslinker. 10.66 μL of crosslinker was combined with

(5) BMP signaling promotes zebrafish heart regeneration via alleviation of replication stressNature communicationsFebruary 17, 2025Vasudevarao MD, Posadas Pena D, Ihle M, Bongiovanni C, Maity P, Geissler D, Mohammadi HF, Rall-Scharpf M, Niemann J, Mommersteeg MTM, et al.(Lonza). After 24 h in the serum-free medium, cells were treated with 50 ng/ml BMP2 or BMP4 (R&D Systems #355-BM-010 and #314-BP-010) solved in 0.1% BSA (Sigma-Aldrich) for 48 h. For γH2A.x staining, U2OS cells were serum

(6) Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal EpitheliumbioRxiv : the preprint server for biologyJanuary 25, 2025Pellon-Cardenas O, Rout P, Hassan S, Fokas E, Ping H, Patel I, Patel J, Plotsker O, Wu A, Kumar R, et al.

(7) Expression of Kielin/chordin-like protein is regulated by BMP-2 in osteoblastsBone reportsSeptember 1, 2024Toba K, Yamada A, Sasa K, Shirota T, Kamijo R.

(8) Mitigation of BMP-induced inflammation in craniofacial bone regeneration and improvement of bone parameters by dietary hesperidinScientific reportsJanuary 31, 2024Miguez PA, de Paiva Gonçalves V, Musskopf ML, Rivera-Concepcion A, McGaughey S, Yu C, Lee DJ, Tuin SA, Ali A.

(9) Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colonCell stem cellNovember 2, 2023Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, et al.

(10) Mitigation of BMP-induced Inflammation in Craniofacial Bone Regeneration and Improvement of Bone Parameters by Dietary HesperidinResearch squareSeptember 29, 2023Miguez P, De Paiva Goncalves V, Musskopf M, Rivera-Concepcion A, McGaughey S, Yu C, Lee DJ, Tui S.

(11) MOBILE pipeline enables identification of context-specific networks and regulatory mechanismsNature communicationsJuly 6, 2023Erdem C, Gross SM, Heiser LM, Birtwistle MR.

(12) Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2FEBS open bioJuly 1, 2023Nagasaki K, Yamada A, Sasa K, Kamijo R.

(13) Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal nicheNature communicationsMay 25, 2023Lin M, Hartl K, Heuberger J, Beccaceci G, Berger H, Li H, Liu L, Müllerke S, Conrad T, Heymann F, et al.

(14) ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survivalThe Journal of biological chemistryApril 1, 2023Das S, Mondal A, Dey C, Chakraborty S, Bhowmik R, Karmakar S, Sengupta A.

(15) Self-Prepared Hyaluronic Acid/Alkaline Gelatin Composite with Nano-Hydroxyapatite and Bone Morphogenetic Protein for Cranial Bone FormationInternational journal of molecular sciencesJanuary 6, 2023Hachinohe Y, Taira M, Hoshi M, Yoshida D, Hatakeyama W, Sawada T, Kondo H.

(16) Bone Formation on Murine Cranial Bone by Injectable Cross-Linked Hyaluronic Acid Containing Nano-Hydroxyapatite and Bone Morphogenetic ProteinPolymersDecember 8, 2022Hachinohe Y, Taira M, Hoshi M, Hatakeyama W, Sawada T, Kondo H.

(17) Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4Developmental cellNovember 21, 2022D'Amato G, Phansalkar R, Naftaly JA, Fan X, Amir ZA, Rios Coronado PE, Cowley DO, Quinn KE, Sharma B, Caron KM, et al.for 16 h. The day after, explants were washed with 1X PBS and recombinant rBMP2 (R&D Systems, Cat. 355-BM-010) or rVegfa (PeproTech, Cat. 450–32) diluted in 2% FBS basal media was added to the explants individually

(18) The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect modelBiomaterialsSeptember 1, 2022Gao X, Hwang MP, Wright N, Lu A, Ruzbarsky JJ, Huard M, Cheng H, Mullen M, Ravuri S, Wang B, et al.

(19) Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancerCell reportsJuly 26, 2022Shonibare Z, Monavarian M, O'Connell K, Altomare D, Shelton A, Mehta S, Jaskula-Sztul R, Phaeton R, Starr MD, Whitaker R, et al.

(20) Highly distinct genetic programs for peripheral nervous system formation in chordatesBMC biologyJune 27, 2022Chowdhury R, Roure A, le Pétillon Y, Mayeur H, Daric V, Darras S.

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BMP-2 Protein

BMP-2 Protein

Recombinant Human/Mouse/Rat BMP-2 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human/Mouse/Rat BMP-2 Protein from R&D Systems, a Bio-Techne Brand

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