Recombinant Human HGF (NS0-expressed) Protein, CF 294-HGN-005/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human HGF (NS0-expressed) Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $272.00Supplier Page View Company Product Page
Catalog Number294-HGN-005/CF
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size5 ug (also 25 ug, 100 ug, 250 ug)
Molecule NameHGF
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 71-85 kDa, nonreducing conditions 56-65 kDa and 30-40 kDa, reducing conditions
Theoretical: alpha chain: 53.7 kDaÃŸ chain: 26 kDa
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human HGF (NS0-expressed) Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesDFNB39, HPTA, F-TCF, SF, HGFB
NCBI Full Gene Namehepatocyte growth factor

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancerOncogeneMay 3, 2024Vinod Kumar, Zachary A. Yochum, Princey Devadassan, Eric H.-B. Huang, Ethan Miller, Roja Baruwal, Purva H. Rumde, Autumn L. GaitherDavis, Laura P. Stabile, Timothy F. Burns(Houston, TX). The ERK inhibitor (LY3214996) was supplied by Eli Lilly and Company. Recombinant Human HGF (294-HGN-005/CF 5 µg) was purchased from R&D Systems (Minneapolis, MN). 4-(Methylnitrosoamino)-1-(3-pyridyl)-1-butanone

(2) MET Oncogene Controls Invasive Growth by Coupling with NMDA ReceptorCancersSeptember 11, 2022Gallo S, Vitacolonna A, Comoglio P, Crepaldi T.

(3) Detection and quantification of human-specific mRNA from hepatocyte-like cells derived from dental pulp using real-time polymerase chain reactionJournal of oral biosciencesSeptember 1, 2021Shimamura N, Fujii K, Ohkoshi S.

(4) cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunitsThe Journal of biological chemistryFebruary 15, 2019Adame-García SR, Cervantes-Villagrana RD, Orduña-Castillo LB, Del Rio JC, Gutkind JS, Reyes-Cruz G, Taylor SS, Vázquez-Prado J.

(5) Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancerProceedings of the National Academy of Sciences of the United States of AmericaOctober 10, 2017Jahangiri A, Nguyen A, Chandra A, Sidorov MK, Yagnik G, Rick J, Han SW, Chen W, Flanigan PM, Schneidman-Duhovny D, et al.Interaction in Cultured Cells. U87 or MDA-MB231 cells were cultured, in bevacizumab (Genentech), HGF (294-HGN-005/CF, R&D Systems), hypoxia, conditioned HUVEC media, or serum-free media containing VEGF165 (584501, Biolegend),

(6) Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3Scientific reportsMarch 2, 2017He H, Kuriyan AE, Su CW, Mahabole M, Zhang Y, Zhu YT, Flynn HW, Parel JM, Tseng SC.

(7) Human Stem Cell-Derived Endothelial-Hepatic Platform for Efficacy Testing of Vascular-Protective Metabolites from NutraceuticalsStem cells translational medicineMarch 1, 2017Narmada BC, Goh YT, Li H, Sinha S, Yu H, Cheung C.

(8) Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesionOncogeneApril 7, 2016Tervonen TA, Belitškin D, Pant SM, Englund JI, Marques E, Ala-Hongisto H, Nevalaita L, Sihto H, Heikkilä P, Leidenius M, et al.

(9) Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplificationBMC cancerFebruary 16, 2016Wang J, Goetsch L, Tucker L, Zhang Q, Gonzalez A, Vaidya KS, Oleksijew A, Boghaert E, Song M, Sokolova I, et al.

(10) Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind METClinical cancer research : an official journal of the American Association for Cancer ResearchMay 1, 2013Basilico C, Pennacchietti S, Vigna E, Chiriaco C, Arena S, Bardelli A, Valdembri D, Serini G, Michieli P.

(11) Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cellsPloS oneAugust 11, 2010Roelandt P, Pauwelyn KA, Sancho-Bru P, Subramanian K, Bose B, Ordovas L, Vanuytsel K, Geraerts M, Firpo M, De Vos R, et al.

(12) Development and validation of sandwich ELISA microarrays with minimal assay interferenceJournal of proteome researchJune 1, 2008Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC.

(13) Hepatocyte growth factor and its role in the pathogenesis of retinal detachmentInvestigative ophthalmology & visual scienceJanuary 1, 2004Jin M, Chen Y, He S, Ryan SJ, Hinton DR.

(14) Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3Cancer researchFebruary 15, 2003Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC.

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Recombinant Human HGF (NS0-expressed) Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human HGF (NS0-expressed) Protein, CF from R&D Systems, a Bio-Techne Brand

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