Recombinant Human CCL2/MCP-1 Protein 279-MC-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human CCL2/MCP-1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $261.00Supplier Page View Company Product Page
Catalog Number279-MC-010
Size10 ug (also 50 ug)
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 10 kDa, reducing conditions
Theoretical: 8.7 kDa
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameCCL2/JE/MCP-1
Source/Expression SystemE. coli-derived Recombinant Human CCL2/MCP-1 Protein
NCBI Full Gene NameC-C motif chemokine ligand 2
NCBI Gene AliasesMCP1, MCAF, HSMCR30, HC11, SMC-CF, GDCF-2, SCYA2, MCP-1
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Chemoattractive potential of stem cells from apical papilla in peripheral blood monocytes: an in vitro studyBrazilian Dental JournalJanuary 19, 2026Alexandre Guimarães dos dos Santos, Letícia Martins Santos, Juliana Garuba Rahhal, Mariane Sloniak, Cristina Cunha Villar, Fernando Neves Nogueira, Carla Renata Siperthuman CCL2 antibody (MAB679-SP, R&D Systems) were also tested. 300 ng/ml of Recombinant Human CCL2 (279-MC-010 R&D Systems) was used for positive control, while α-MEM 10% was the negative control. After 24 hours,

(2) Characterization of a pathogenic nonmigratory fibroblast population in systemic sclerosis skinJCI insightMay 22, 2025Clark KE, Xu S, Attar M, Ong VH, Buckley CD, Denton CP.

(3) Hesperetin mitigates adipose tissue inflammation to improve obesity-associated metabolic healthInternational immunopharmacologyMarch 6, 2025Chen Q, Chen W, Zhang B, Xue L, Li F, Zhang L, Tong H, Zhu Q.

(4) Migration arrest and transendothelial trafficking of human pathogenic-like Th17 cells are mediated by differentially positioned chemokinesNature communicationsFebruary 26, 2025Parween F, Singh SP, Kathuria N, Zhang HH, Ashida S, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, et al.throughout the assays. For treatment of T cells with CCL2, recombinant human CCL2 (100 ng/mL, Cat# 279-MC-010; R&D Systems) was added to the cells immediately before loading them into the flow chamber and the CCL2

(5) Personalized Vascularized Models of Breast Cancer Desmoplasia Reveal Biomechanical Determinants of Drug Delivery to the TumorAdvanced science (Weinheim, Baden-Wurttemberg, Germany)October 1, 2024Offeddu GS, Cambria E, Shelton SE, Haase K, Wan Z, Possenti L, Nguyen HT, Gillrie MR, Hickman D, Knutson CG, et al.(#208‐IL‐010, R&D Systems), IL12 (#219‐IL‐005, R&D Systems), TNFα (#210‐TA‐005, R&D Systems), CCL2 (#279‐MC‐010, R&D Systems), CCL4 (#271‐BME‐010, R&D Systems) were perfused at a concentration of 5 ng mL−1 together

(6) Profiling migration of human monocytes in response to chemotactic and barotactic guidance cuesCell Reports MethodsSeptember 16, 2024Clare K. Hall, Olivia M. Barr, Antoine Delamare, Alex Burkholder, Alice Tsai, Yuyao Tian, Felix E. Ellett, Brent M. Li, Rudolph E. Tanzi, Mehdi JorfiFigure Legends. Method details Priming of MAP chips CC motif chemokine Ligand 2 (CCL2) (R&D Systems, 279-MC-010) or CCL5 (R&D Systems, 278-RN-010) was reconstituted in IMDM +20% FBS to a final concentration of 100

(7) CD14+CD16+ monocyte transmigration across the blood-brain barrier is associated with HIV-NCI despite viral suppressionJCI insightSeptember 10, 2024Veksler V, Leon-Rivera R, Fleysher L, Gonzalez J, Lopez JA, Rubin LH, Morgello S, Berman JW.

(8) Chemokine-mediated cell migration into the central nervous system in progressive multifocal leukoencephalopathyCell Reports MedicineJuly 16, 2024Marie Deffner, Tilman Schneider-Hohendorf, Andreas Schulte-Mecklenbeck, Simon Falk, I-Na Lu, Patrick Ostkamp, Louisa Müller-Miny, Eva Maria Schumann, Susan Goelz, Ellen Cahir-McFarland, et al.PB-LU-000-0002-00 Recombinant human TNFα,R&D Systems,Cat# 210-TA-005 Recombinant human CCL2,R&D Systems,Cat# 279-MC-010 Recombinant human CCL3,R&D Systems,Cat# 270-LD-010 Recombinant human CCL5,R&D Systems,Cat# 278-RN-010 Recombinant

(9) Nanoparticles of Lactiplantibacillus plantarum K8 Reduce Staphylococcus aureus Respiratory Infection and Tumor Necrosis Factor Alpha- and Interferon Gamma-Induced Lung InflammationNutrientsNovember 9, 2023Hong J, Son M, Sin J, Kim H, Chung DK.

(10) Luteolin ameliorates DSS-induced colitis in mice via suppressing macrophage activation and chemotaxisInternational immunopharmacologyNovember 1, 2023Xue L, Jin X, Ji T, Li R, Zhuge X, Xu F, Quan Z, Tong H, Yu W.

(11) Infiltrating CD8(+) T cells exacerbate Alzheimer's disease pathology in a 3D human neuroimmune axis modelNature neuroscienceSeptember 1, 2023Jorfi M, Park J, Hall CK, Lin CJ, Chen M, von Maydell D, Kruskop JM, Kang B, Choi Y, Prokopenko D, et al.the chemoattractant of interest (R&D Systems; monocyte chemotactic protein (MCP)-1/CCL2, catalog no. 279-MC-010; C-X-C motif chemokine ligand 10 (CXCL10), catalog no. 266-IP-010; and C-X-C motif chemokine ligand

(12) Prognostic impact and gene expression analysis of peri-tumoral alveolar macrophage in resected lung adenocarcinomaCancer scienceAugust 1, 2023Kagawa Y, Nakai T, Taki T, Hashimoto H, Tanaka Y, Sakai T, Shibata Y, Izumi H, Nosaki K, Udagawa H, et al.

(13) Inflammation of Dry Eye Syndrome: A Cellular Study of the Epithelial and Macrophagic Involvement of NFAT5 and RAGEInternational journal of molecular sciencesJuly 4, 2023Henrioux F, Navel V, Belville C, Charnay C, Antoine A, Chiambaretta F, Sapin V, Blanchon L.

(14) Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cellsbioRxiv : the preprint server for biologyFebruary 13, 2023Parween F, Singh SP, Zhang HH, Kathuria N, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, Lorenzi HA, et al.ng/ml throughout the assays. For treatment of T cells with CCL2, recombinant human CCL2 (100 ng/ml, 279-MC-010; R&D Systems) was added to the cells immediately before loading them into the flow chamber and the CCL2

(15) Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding functionPloS oneJanuary 1, 2023Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, Powers M, Wang J, Dower C, Hegen M, et al.

(16) GPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophagesNature communicationsNovember 25, 2022Yan J, Zhang Y, Yu H, Zong Y, Wang D, Zheng J, Jin L, Yu X, Liu C, Zhang Y, et al.

(17) Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancerOncology lettersNovember 1, 2022Tobiume M, Mitsuhashi A, Saijo A, Ogino H, Afroj T, Ogawa H, Goto H, Sato S, Abe A, Haji K, et al.previously described (13,17). Recombinant human CXCL12/SDF-1 (350-NS-010/CF; R&D Systems), CCL2/MCP-1 (279-MC-010; R&D Systems), PDGF-AA, or PDGF-BB (221-AA-010, 220-BB-010; R&D Systems) was used as a chemoattractant.

(18) Early Emergence of 5' Terminally Deleted Coxsackievirus-B3 RNA Forms Is Associated with Acute and Persistent Infections in Mouse Target TissuesVaccinesJuly 28, 2022Callon D, Lebreil AL, Bouland N, Fichel C, Fornès P, Andreoletti L, Berri F.

(19) Chronic Low Dose Morphine Does Not Alter Two In Vitro BBB ModelsBrain sciencesJuly 6, 2022Marino J, Maubert ME, Lawrence JM, Wigdahl B, Nonnemacher MR.

(20) Inhibition of Vascular Endothelial Cadherin Cleavage Prevents Elastic Fiber Alterations and Atherosclerosis Induced by Intermittent Hypoxia in the Mouse AortaInternational journal of molecular sciencesJune 24, 2022Harki O, Bouyon S, Sallé M, Arco-Hierves A, Lemarié E, Demory A, Chirica C, Vilgrain I, Pépin JL, Faury G, et al.

Be the First to Write a Review!

Recombinant Human CCL2/MCP-1 Protein

CCL2/JE/MCP-1 Protein

CCL2/JE/MCP-1 Protein

CCL2/JE/MCP-1 Protein

CCL2/JE/MCP-1 Protein

Recombinant Human CCL2/MCP-1 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

Citations (117)

Reviews

Recombinant Human CCL2/MCP-1 Protein from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map