Recombinant Human SCF Protein 255-SC-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human SCF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $298.00Supplier Page View Company Product Page
Catalog Number255-SC-010
SpeciesHuman
Molecule NameSCF/c-kit Ligand
Size10 ug (also 50 ug, 200 ug, 1 mg)
Source/Expression SystemE. coli-derived Recombinant Human SCF Protein
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
NCBI Full Gene NameKIT ligand
NCBI Gene AliasesSCF, SHEP7, MGF, FPHH, KL-1, Kitl, DCUA, DFNA69, WS2F, SLF, FPH2, SF
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 17-18 kDa, under reducing condtitions
Theoretical: 19 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) TRIM10β upregulation promotes microtubule destabilization and triggers proteotoxic stressCellular signallingNovember 1, 2025Kim H, Shin W, Jeon B, Lee S, Park B.

(2) Blastemia portrays a poor prognosis in acute leukemia patients with invasive pulmonary aspergillosisJournal of InfectionAugust 1, 2025Sung-Yeon Cho, Sebastian Wurster, Ying Jiang, Alexandre Bazinet, Yang Hui, Russel E. Lewis, Takahiro Matsuo, Nathaniel Albert, Guillermo Garcia-Manero, Dimitrios P. Kontoyiannis#35050061), 50 ng/ml thrombopoietin (TPO) (R&D systems, #288-TP-025), 100 ng/ml SCF (R&D systems, #255-SC-010), and 40 ng/ml FLT-3 ligand (R&D systems, #308-FK-005). In-vitro experiments For direct co-culture

(3) In cellulo DNA assembly for targeted genomic integration and rearrangement in human cellsbioRxiv : the preprint server for biologyJune 16, 2025Levesque S, Kawashima N, Hwang G, Becerra B, Schoonenberg VAC, Mannherz W, Homfeldt L, Pinello L, Agarwal S, Bauer DE.

(4) Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor ProgressionCancer discoveryMay 2, 2025Oñate MK, Oon C, Bhattacharyya S, Low V, Chen C, Zhao X, Arnold F, Yan Z, Pramod S, Hang Y, et al.treated with recombinant KITL/SCF at the final concentration of 100 ng/mL: human SCF (R&D Systems, 255-SC-010) or mouse KITL/SCF (R&D Systems, 455-MC-010). Plates were replenished with recombinant KITL/SCF daily

(5) Human pluripotent stem cell-derived microglia shape neuronal morphology and enhance network activity in vitroJournal of neuroscience methodsMarch 1, 2025Kok LML, Helwegen K, Coveña NF, Heine VM.

(6) FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestriesNature communicationsMarch 1, 2025Wonkam A, Esoh K, Levine RM, Ngo Bitoungui VJ, Mnika K, Nimmagadda N, Dempsey EAD, Nkya S, Sangeda RZ, Nembaware V, et al.

(7) BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugateCell stem cellFebruary 6, 2025Demirci S, Zeng J, Palchaudhuri R, Wu C, Abraham DM, Hayal TB, Essawi K, Nguyen MA, Stasula U, Chu R, et al.

(8) Stage-specific CAR-mediated signaling generates naïve-like, TCR-null CAR T cells from induced pluripotent stem cellsbioRxiv : the preprint server for biologyNovember 28, 2024Yoo SP, Yuan X, Engstrom C, Chang P, Li S, Lathrop L, Lagosh J, Seet C, Kohn DB, Crooks GM.

(9) Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cellsCell reportsAugust 27, 2024Kent GM, Atkins MH, Lung B, Nikitina A, Fernandes IM, Kwan JJ, Andrews TS, MacParland SA, Keller GM, Gage BK.

(10) Primitive macrophages enable long-term vascularization of human heart-on-a-chip platformsCell stem cellAugust 1, 2024Landau S, Zhao Y, Hamidzada H, Kent GM, Okhovatian S, Lu RXZ, Liu C, Wagner KT, Cheung K, Shawky SA, et al.

(11) An enhancer RNA recruits KMT2A to regulate transcription of MybCell reportsJuly 23, 2024Kim J, Diaz LF, Miller MJ, Leadem B, Krivega I, Dean A.

(12) HELQ deficiency impairs the induction of primordial germ cell‐like cellsFEBS Open BioJuly 1, 2024Cong Wan, Yaping Huang, Xingguo Xue, Gang Chang, Mei Wang, Xiao‐Yang Zhao, Fang Luo, Zhi‐Zhong Tangmm β‐mercaptoethanol) supplemented with 200 ng·mL−1 BMP4 (314‐BP‐010; R&D Systems), 100 ng·mL−1 SCF (255‐SC‐010; R&D Systems), 50 ng·mL−1 EGF (236‐EG; R&D Systems), 100 ng·mL−1 LIF (7734‐LF‐500’ R&D Systems) and

(13) Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteriesbioRxiv : the preprint server for biologyJune 12, 2024Abello J, Yin Y, Zhao Y, Maurer J, Lee J, Bodell C, Clevenger AJ, Burton Z, Goeckel ME, Lin M, et al.

(14) Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and diseaseCell Stem CellJune 6, 2024Biao Huang, Zipeng Zeng, Sunghyun Kim, Connor C. Fausto, Kari Koppitch, Hui Li, Zexu Li, Xi Chen, Jinjin Guo, Chennan C. Zhang, et al.(S1P),Sigma-Aldrich,Cat# S9666-1MG Lysophosphatidic acid (LPA),Sigma-Aldrich,Cat# L7260-1MG SCF,R&D Systems,Cat# 255-SC-010 IGF-1,Sigma-Aldrich,Cat# I1271-.1MG IGF-2,Peprotech,Cat# AF-100-12 Mouse LIF,Millipore,Cat# ESG1107 Human

(15) Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1bioRxiv : the preprint server for biologyApril 1, 2024Johnson D, Colijn S, Richee J, Yano J, Burns M, Davis AE, Pham VN, Saric A, Jain A, Yin Y, et al.

(16) Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progressionNature communicationsMarch 5, 2024Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Grant Rowe R, Wainwright DA, McCortney K, et al.

(17) PD-L1 regulates inflammatory programs of macrophages from human pluripotent stem cellsLife Science AllianceFebruary 1, 2024Handi Cao, Yang Xiang, Shihui Zhang, Yiming Chao, Jilong Guo, Theo Aurich, Joshua WK Ho, Yuanhua Huang, Pentao Liu, Ryohichi SugimuraSTEMCELL Technologies), including 5 ng/ml IL-3 (catalog no. 203-IL-010; R&D Systems), 20 ng/ml SCF (catalog no. 255-SC-010; R&D Systems), and 10 ng/ml FLT3L (catalog no. 308-FK-005; R&D Systems), and cultured organoids for

(18) CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cell developmentPLoS geneticsDecember 1, 2023Hwang YS, Seita Y, Blanco MA, Sasaki K.GK15 medium supplemented with 200 ng/ml BMP4 (R&D Systems, 314-BP-010), 100 ng/ml SCF (R&D Systems, 255-SC-010), 50 ng/ml EGF (R&D Systems, 236-EG), 10 ng/ml LIF (Millipore, #LIF1010) and 10 μM of Y-27632 (GK15+BSELY).

(19) LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progressionResearch squareOctober 5, 2023Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Rowe RG, Wainwright D, McCortney K, et al.

(20) Factors Influencing Marker Expressions of Cultured Human Cord Blood-Derived Mast CellsInternational journal of molecular sciencesOctober 4, 2023Alimohammadi S, Masuda-Kuroki K, Szöllősi AG, Di Nardo A.

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SCF/c-kit Ligand Protein

SCF/c-kit Ligand Protein

SCF/c-kit Ligand Protein

SCF/c-kit Ligand Protein

Recombinant Human SCF Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human SCF Protein from R&D Systems, a Bio-Techne Brand

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