Recombinant Mouse CD28 Fc Chimera Protein 483-CD-200 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse CD28 Fc Chimera Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $504.00Supplier Page View Company Product Page
Catalog Number483-CD-200
SpeciesMouse
Size200 ug
Molecule NameCD28
NCBI Full Gene NameCD28 antigen
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 60 kDa, reducing conditions
Theoretical: 52 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse CD28 Fc Chimera Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) A B7-H3-Targeted CD28 Bispecific Antibody Enhances the Activity of Anti-PD-1 and CD3 T-cell Engager ImmunotherapiesMolecular cancer therapeuticsMarch 4, 2025Moore GL, Zeng VG, Diaz JE, Bonzon C, Avery KN, Rashid R, Qi J, Nam DH, Jacinto J, Dragovich MA, et al.

(3) Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunityNatureMay 7, 2015Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, et al.

(5) Cutting edge: chronic inflammatory liver disease in mice expressing a CD28-specific ligandJournal of immunology (Baltimore, Md. : 1950)January 15, 2013Corse E, Gottschalk RA, Park JS, Sepulveda MA, Loke P, Sullivan TJ, Johnson LK, Allison JP.

(6) Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1The Journal of biological chemistryJuly 4, 2008Yamashita T, Ohneda K, Nagano M, Miyoshi C, Kaneko N, Miwa Y, Yamamoto M, Ohneda O, Fujii-Kuriyama Y.

(7) CD86 regulates IgG1 production via a CD19-dependent mechanismJournal of immunology (Baltimore, Md. : 1950)August 1, 2007Kin NW, Sanders VM.

(8) BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammationJournal of immunology (Baltimore, Md. : 1950)February 1, 2007Arnett HA, Escobar SS, Gonzalez-Suarez E, Budelsky AL, Steffen LA, Boiani N, Zhang M, Siu G, Brewer AW, Viney JL.

Recombinant Mouse CD28 Fc Chimera Protein from R&D Systems, a Bio-Techne Brand