Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein 377-HB-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNeuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $415.00Supplier Page View Company Product Page
Catalog Number377-HB-050/CF
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Source/Expression SystemE. coli-derived Recombinant Human NRG1-beta 1/HRG1-beta 1 ECD Protein, CF
Size50 ug
Molecule NameNeuregulin-1 beta 1/NRG1 beta 1
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight26.9 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameneuregulin 1
NCBI Gene AliasesARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF

Specifications/Features

Available conjugates: Sizes Available: 50 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Neuregulin-1/ErbB4 signaling modulates Plasmodium falciparum HRP2-induced damage to brain cortical organoidsiScienceJune 17, 2022Harbuzariu A, Nti A, Harp KO, Cespedes JC, Driss A, Stiles JK.sodium azide, while NRG1/carrier free (no bovine serum albumin added in its preparation) (Biotechne cat#377-HB-050/CF, Minneapolis, MN) is commercially available as lyophilized powder and was reconstituted in sterile PBS.

(2) Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancersBreast cancer research : BCRAugust 9, 2018Osada T, Hartman ZC, Wei J, Lei G, Hobeika AC, Gwin WR, Diniz MA, Spector N, Clay TM, Chen W, et al.

(3) Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysisNatureApril 5, 2018Scapin G, Dandey VP, Zhang Z, Prosise W, Hruza A, Kelly T, Mayhood T, Strickland C, Potter CS, Carragher B.

(4) Uridine-5'-Triphosphate Partially Blocks Differentiation Signals and Favors a more Repair State in Cultured rat Schwann CellsNeuroscienceFebruary 21, 2018Palomo-Guerrero M, Cosgaya JM, Gella A, Casals N, Grijota-Martinez C.

(5) Identification of Anti-EGFR and Anti-ErbB3 Dual Variable Domains Immunoglobulin (DVD-Ig) Proteins with Unique ActivitiesPloS oneJanuary 1, 2015Gu J, Yang J, Chang Q, Liu Z, Ghayur T, Gu J.

(6) Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injuryStem cells translational medicineMarch 1, 2014Gericota B, Anderson JS, Mitchell G, Borjesson DL, Sturges BK, Nolta JA, Sieber-Blum M.

(7) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(8) Cellular effects of HER3-specific affibody moleculesPloS oneJanuary 1, 2012Göstring L, Malm M, Höidén-Guthenberg I, Frejd FY, Ståhl S, Löfblom J, Gedda L.

(9) Human epidermal neural crest stem cells (hEPI-NCSC)--characterization and directed differentiation into osteocytes and melanocytesStem Cell Reviews and ReportsNovember 1, 2011Oliver Clewes, Alla Narytnyk, Kevin R. Gillinder, Andrew D. Loughney, Alison P. Murdoch, Maya Sieber-BlumBMP2 (Cat# 355-BEC-010/CF), NGF (Cat# 256-GF-100/CF), TGF-β2 (Cat# 302-B2-002/CF), Neuregulin-1 (Cat# 377-HB-050/CF) and CNTF (Cat# 257-NT-010/CF). Forskolin was from Sigma (Cat# F6886). Cultures were fixed with 4% PFA

(10) Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in miceThe Journal of clinical investigationAugust 1, 2010Casazza A, Finisguerra V, Capparuccia L, Camperi A, Swiercz JM, Rizzolio S, Rolny C, Christensen C, Bertotti A, Sarotto I, et al.

(11) An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cellsCancer cellMarch 16, 2010Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, Moustafa Z, Thomas RK, Greulich H, Schinzel A, et al.

(12) ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migrationThe Journal of cell biologyApril 21, 2008Yamauchi J, Miyamoto Y, Chan JR, Tanoue A.

(13) Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancerCancer cellJuly 1, 2006Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, et al.

(14) Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiationStem cells and developmentJune 1, 2006Barkho BZ, Song H, Aimone JB, Smrt RD, Kuwabara T, Nakashima K, Gage FH, Zhao X.

(15) Neuregulin-1-beta1 enters brain and spinal cord by receptor-mediated transportJournal of neurochemistryFebruary 1, 2004Kastin AJ, Akerstrom V, Pan W.

(16) Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelinationeLifeJanuary 1, 0001"Della-Flora Nunes G, Wilson ER, Hurley E, He B, O'Malley BW, Poitelon Y, Wrabetz L, Feltri ML."

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Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein

Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (16)

Reviews

Neuregulin-1 beta 1/NRG1 beta 1 Extracellular Domain Protein from R&D Systems, a Bio-Techne Brand

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