Recombinant Human CD25/IL-2R alpha Protein 223-2A-005 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human CD25/IL-2R alpha Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $241.00Supplier Page View Company Product Page
Catalog Number223-2A-005
SpeciesHuman
Molecule NameCD25/IL-2R alpha
Size5 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 36 kDa, reducing conditions
Theoretical: 22 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
NCBI Full Gene Nameinterleukin 2 receptor subunit alpha
NCBI Gene AliasesIMD41, CD25, TCGFR, IL2R, p55, IDDM10
Source/Expression SystemNS0-derived Recombinant Human CD25/IL-2R alpha Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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(1) Increased sIL-2RÎ± leads to obstruction of IL-2 biological function and Treg cells differentiation in SLE patients via binding to IL-2Frontiers in ImmunologySeptember 20, 2022Dan Long, Shujiao Yu, Lu Zhang, Yang Guo, Shumin Xu, Yuting Rao, Zikun Huang, Qing Luo, Junming LiGlutamine and IL-2 (6 pg/ml), followed by treatment with recombinant human sIL-2Rα (R&D Systems, Cat. No. 223-2A-005) at final concentrations of 0, 10, 25, 50, 100, 250, 500, 1×103, 5×103, 1×104, 2.5×104, and 5×104 pg/ml,

(2) An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancerNature communicationsDecember 22, 2020Sahin D, Arenas-Ramirez N, Rath M, Karakus U, Hümbelin M, van Gogh M, Borsig L, Boyman O.

Recombinant Human CD25/IL-2R alpha Protein from R&D Systems, a Bio-Techne Brand