Recombinant Human ICOS Fc Chimera Protein, CF 169-CS-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human ICOS Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $412.00Supplier Page View Company Product Page
Catalog Number169-CS-050
Size50 ug
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 50-60 kDa, reducing conditions
Theoretical: 40.3 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameICOS
Source/Expression SystemNS0-derived Recombinant Human ICOS Fc Chimera Protein, CF
NCBI Full Gene Nameinducible T cell costimulator
NCBI Gene AliasesCVID1, AILIM, CD278
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Involvement of CD40-CD40L and ICOS-ICOSL in the development of chronic rhinosinusitis by targeting eosinophilsFrontiers in immunologyJanuary 1, 2023Zhou A, Shi C, Fan Y, Zheng Y, Wang J, Liu Z, Xie H, Liu J, Jiao Q.6420-CL-025) or recombinant human ICOS protein (rhICOS, 10 µg/ml; R&D Systems, Minneapolis, MN, USA, 169-CS-050). IgG (5 µg/ml; R&D Systems, Minneapolis, MN, USA, 1-001-A) was used as control. Cells were harvested

(2) Orthogonal quantification of soluble inducible T-cell costimulator (ICOS) in healthy and diseased human serumJournal of pharmaceutical analysisApril 1, 2022McKinski K, McNulty D, Zappacosta F, Birchler M, Szapacs M, Evans C.

(3) Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonistThe Journal of clinical investigationApril 1, 2019Koh KH, Cao Y, Mangos S, Tardi NJ, Dande RR, Lee HW, Samelko B, Altintas MM, Schmitz VP, Lee H, et al.

(4) Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodiesmAbsOctober 1, 2018Sasso E, D'Avino C, Passariello M, D'Alise AM, Siciliano D, Esposito ML, Froechlich G, Cortese R, Scarselli E, Zambrano N, et al.TIGIT/Fc (9464-TG-050); OX40/Fc (3388-OX-050); 4-1BB/Fc (838-4B-100); CD27/Fc (382-CD-10) and ICOS/Fc (169-CS-050); – human IgG1-Fc, 110-HG-100 (all from R&D Systems). Cell cultures MDA-MB-231 cells were cultured

(5) ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naïve CD4+ T cellsEuropean journal of immunologyOctober 1, 2006Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, et al.

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Recombinant Human ICOS Fc Chimera Protein, CF

ICOS Fc Chimera Protein

Recombinant Human ICOS Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human ICOS Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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