Recombinant Human IL-8/CXCL8 Protein, CF 208-IL-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-8/CXCL8 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $191.00Supplier Page View Company Product Page
Catalog Number208-IL-010/CF
Size10 ug (also 50 ug)
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular Weight8 kDa
Conjugate/TagUnconjugated
SpeciesHuman
Source/Expression SystemE. coli-derived Recombinant Human IL-8/CXCL8 Protein, CF
Molecule NameIL-8/CXCL8
NCBI Full Gene NameC-X-C motif chemokine ligand 8
NCBI Gene AliasesLUCT, MDNCF, GCP1, NAF, GCP-1, NAP1, SCYB8, LYNAP, NAP-1, LECT, MONAP, IL8
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) ERG-deficient endothelium identifies IL-8/CXCR2 axis as a therapeutic target for resolving neutrophilic lung vascular injuryJCI InsightApril 8, 2026Vigneshwaran Vellingiri, Vijay Avin Balaji Balaji Ragunathrao, Jagdish Chandra Joshi, Md Zahid Akhter, Mumtaz Anwar, Somenath Banerjee, Sayanti Datta, Viktor Pinneker, Steven M. Dudek, Yoshikazu Tsukasaki, et al.assessed using commercially available assay kits (Recombinant Human IL-8/CXCL8 Protein, R&D Systems, 208-IL-010/CF), according to the manufacturers’ instructions. MPO assay and immunostaining MPO activity in Ergfl/fl

(2) The adult nasal mucosa is defined by distinct immune profiles that modulate in-vitro SARS-CoV-2 infectionResearch SquareJanuary 29, 2026Sarah N Gowanlock, Victor HK Lam, Zeynep Güneş Tepe, Daniel E Park, Vera Tai, Juan E Salazar, Tony Pham, Yazan Khan, Sydney Nelson, Caitlin Horn, et al.ng/mL; 210-TA-020/CF, R&D Systems), IP-10 (400 ng/mL; 266-IP-010/CF, R&D Systems), IL-8 (200 ng/mL; 208-IL-010/CF, R&D Systems), and MIG (400 ng/mL; 392-MG-010/CF, R&D Systems). The IFN-high IPT cocktail consisted

(3) Monocyte adhesion to and transmigration through endothelium following cardiopulmonary bypass shearing is mediated by IL-8 signalingFrontiers in cardiovascular medicineJanuary 1, 2024Zhou H, Scatena M, Tu LN, Giachelli CM, Nigam V.SML2655-5MG) for 30 min or 200 ng/ml of recombinant human IL-8 (R&D Systems, Minneapolis, MN, Cat # 208-IL-010/CF) for 1 h. G-THP-1 cells or hPBMCs, sheared or statically incubated, were then added to a monolayer of

(4) ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysisNat CommunDecember 11, 2023Zülal Cibir, Jacqueline Hassel, Justin Sonneck, Lennart Kowitz, Alexander Beer, Andreas Kraus, Gabriel Hallekamp, Martin Rosenkranz, Pascal Raffelberg, Sven Olfen, et al.R&D Systems, Minneapolis, MN, USA), or 2 μl human recombinant CXCL8 (final concentration: 100 ng/ml; Cat. No.: 208-IL-010/CF, R&D Systems). As all stimuli were reconstituted in sterile PBS, the addition of 2 μl PBS alone served

(5) Tissue CD14(+)CD8(+) T cells reprogrammed by myeloid cells and modulated by LPSNatureFebruary 1, 2023Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, et al.

(6) Adipose tissue from subjects with type 2 diabetes exhibits impaired capillary formation in response to GROα: involvement of MMPs-2 and -9AdipocyteDecember 31, 2022Yifat Amir Levy, Theodore P Ciaraldi, Sunder R. Mudaliar, Susan A. Phillips, Robert R. Henrycultured in 1:1 EGM-2-MV (Lonza) and α-MEM (Life-Technologies/Gibco,). Explants were treated with rIL8 (#208-IL-010/CF), rGROα (#275–GR–010), and rIL15 (#247-ILB-005) (all recombinant proteins are human low-endotoxin from

(7) DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signalingJournal of leukocyte biologySeptember 1, 2022Capitano ML, Sammour Y, Ropa J, Legendre M, Mor-Vaknin N, Markovitz DM.

(8) Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistanceCell reportsJuly 19, 2022Islam R, Mishra J, Polavaram NS, Bhattacharya S, Hong Z, Bodas S, Sharma S, Bouska A, Gilbreath T, Said AM, et al.

(9) A humanized β(2) integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivoCell reportsMay 31, 2022Wen L, Marki A, Wang Z, Orecchioni M, Makings J, Billitti M, Wang E, Suthahar SSA, Kim K, Kiosses WB, et al.

(10) Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypassJournal of leukocyte biologyApril 1, 2022Lesouhaitier M, Gregoire M, Gacouin A, Coirier V, Frerou A, Piau C, Cattoir V, Dumontet E, Revest M, Tattevin P, et al.

(11) On the origin of metastases: Induction of pro-metastatic states after impending cell death via ER stress, reprogramming, and a cytokine stormCell reportsMarch 8, 2022Conod A, Silvano M, Ruiz I Altaba A.

(12) Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cellsScientific reportsJuly 22, 2021Lee J, Choi JA, Ju HH, Kim JE, Paik SY, Rao PV.

(13) Granulocyte and monocyte adsorptive apheresis induces apoptosis of neutrophils and release of a novel chemoattractant for desensitization of interleukin-8 response - In vitro and in vivo resultsCytokineMarch 1, 2021Kashiwagi N, Saito F, Maegawa H, Kaneda K.

(14) Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel diseaseGut microbesJanuary 1, 2021Li G, Lin J, Zhang C, Gao H, Lu H, Gao X, Zhu R, Li Z, Li M, Liu Z.Trichostatin A (TSA; Cat: S1045) was purchased from Selleck (Houston, TX, USA). Recombinant Human IL-8 protein (Cat: 208-IL-010/CF) was purchased from R&D systems (Minneapolis, MN, USA). DSS (36–50 kDa, Cat: 9011–18-1) was purchased

(15) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune responseProceedings of the National Academy of Sciences of the United States of AmericaNovember 17, 2020Biasci D, Smoragiewicz M, Connell CM, Wang Z, Gao Y, Thaventhiran JED, Basu B, Magiera L, Johnson TI, Bax L, et al.

(16) Pirfenidone regulates LPS mediated activation of neutrophilsScientific reportsNovember 17, 2020Evani SJ, Karna SLR, Seshu J, Leung KP.

(17) Relative Deficiency of Anti-Inflammatory N-Acylethanolamines Compared to Prostaglandins in Oral Lichen PlanusBiomedicinesNovember 6, 2020Rankin L, Gouveia-Figueira S, Danielsson KP, Fowler CJ.

(18) Unique Molecular Characteristics of Visceral Afferents Arising from Different Levels of the Neuraxis: Location of Afferent Somata Predicts Function and Stimulus Detection ModalitiesThe Journal of neuroscience : the official journal of the Society for NeuroscienceSeptember 16, 2020Meerschaert KA, Adelman PC, Friedman RL, Albers KM, Koerber HR, Davis BM.

(19) Chemotherapy-Induced IL8 Upregulates MDR1/ABCB1 in Tumor Blood Vessels and Results in Unfavorable OutcomeCancer researchJuly 15, 2020Kikuchi H, Maishi N, Annan DA, Alam MT, Dawood RIH, Sato M, Morimoto M, Takeda R, Ishizuka K, Matsumoto R, et al.

(20) Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinibBMC cancerJuly 13, 2020Bornemann L, Schuster M, Schmitz S, Sobczak C, Bessen C, Merz SF, Jöckel KH, Haverkamp T, Gunzer M, Göthert JR.R&D Systems, Minneapolis, MN, USA), or 2 μl human recombinant CXCL8 (final concentration: 100 ng/ml; Cat. No.: 208-IL-010/CF, R&D Systems). As all stimuli were reconstituted in sterile PBS, the addition of 2 μl PBS alone served

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Recombinant Human IL-8/CXCL8 Protein, CF

IL-8/CXCL8 Protein

IL-8/CXCL8 Protein

IL-8/CXCL8 Protein

IL-8/CXCL8 Protein

Recombinant Human IL-8/CXCL8 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human IL-8/CXCL8 Protein, CF from R&D Systems, a Bio-Techne Brand

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