Recombinant Human IL-2 Protein, CF 202-IL-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-2 Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $269.00Supplier Page View Company Product Page
Catalog Number202-IL-010/CF
Size10 ug (also 50 ug)
ApplicationsBioactivity
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 13 kDa, under reducing conditions.
Theoretical: 15 kDa
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameIL-2
Source/Expression SystemE. coli-derived Recombinant Human IL-2 Protein, CF
NCBI Full Gene Nameinterleukin 2
NCBI Gene Aliaseslymphokine, TCGF, IL-2
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Protocol for the generation of a human-derived nasal epithelial model and induction of tissue-resident memory-like T cells in a co-culture systemSTAR ProtocolsMarch 20, 2026Lisa A. King, Iris van der Valk, Jasmijn S. Schrumpf, Youvika Singh, Geert H. Groeneveld, Pieter S. Hiemstra, Anne M. van der Does, Simon P. Jochems, Wesley Huisman(FCS),Serana,S-FBS-CO-015 Human serum,Sanquin (contract code: NVT0038),E8813R00 Recombinant human IL-2 protein,R&D Systems,202-IL-010/CF Dimethyl Sulfoxide (DMSO),Sigma-Aldrich,34943-1L "Formalin (formaldehyde solution, 37% in H2O)",Sigma-Aldrich,F1635-500mL Bovine

(2) Trsp is required by regulatory T cells to prevent lethal autoimmunity in micebioRxivJanuary 16, 2026Justin Jacobse, Jennifer M. Pilat, Anna Brooke Harris, Aaron Kwag, Zaryab Aziz, Channing Chi, Sam Schaefer, M. Diana Neely, Matthew A. Buendia, Andrew Pahnke, et al.for 5 minutes at 37°C, 5% CO2, then stimulated with 20 ngmL−1 recombinant mouse IL-2 (R&D Systems, #202-IL-010/CF) for 15 minutes at 37° C, 5% CO2. After stimulation, cells were fixed with warm Phosflow™ Fix Buffer I

(3) Elucidation of B-cell specific drug immunogenicity liabilities via a novel ex vivo assayFront ImmunolJune 4, 2025Cary M. Looney, Axel Ducret, Guido Steiner, Karen Dernick, Katharina Hartman, Michel Siegel, Timothy Hickling, Alex Odermatt, Céline Marban-Doran5 μM Class A CpG (ODN 2216; LabForce customized, LABtlrl-2216-1) and 20 ng/mL of IL-2 (R&D Systems, 202-IL-010/CF) and IL-4 (R&D Systems, 6507-IL-010/CF), with either no antigen as a control or 100 μg/mL antigen. The

(4) CD39 Is Expressed on Functional Effector and Tissue-resident Memory CD8+ T CellsThe Journal of ImmunologySeptember 1, 2024Jordan F. Isaacs, Hanna N. Degefu, Tiffany Chen, Sierra A. Kleist, Shawn C. Musial, Myles A. Ford, Tyler G. Searles, Chun-Chieh Lin, Alexander G. J. Skorput, Keisuke Shirai, et al.Cells were treated with POM-1 (Tocris cat #2689, 50uM), recombinant human IL-2 (R&D systems, cat # 202-IL-010/CF, 50 units/mL), and SIINFEKL peptide (0.5ug, Biomatik) for 3 days. ‘Untreated’ activated OT-I T cells

(5) Internalization of therapeutic antibodies into dendritic cells as a risk factor for immunogenicityFrontiers in ImmunologyAugust 28, 2024Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katharina Hartman, Cary M. Looney, Olivier Rohr, Timothy P. Hickling, Hubert Kettenberger, Martin Lechmann, et al.autologous moDCs incubated with one of the antibody variants or KLH, 10 U/mL of IL-2 (R&D Systems #202-IL-010/CF) and 5 ng/mL of IL-7 (R&D Systems #207-IL-010/CF). At day 21, the specificity of the CD4+ T cells was

(6) Temozolomide and the PARP Inhibitor Niraparib Enhance Expression of Natural Killer Group 2D Ligand ULBP1 and Gamma-Delta T Cell Cytotoxicity in GlioblastomaCancersAugust 15, 2024Jones AB, Tuy K, Hawkins CC, Quinn CH, Saad J, Gary SE, Beierle EA, Ding L, Rochlin KM, Lamb LS, et al.deltas T cells were stimulated using 400 IU/mL of IL-2 (R&D Systems, Minneapolis, MN, USA; cat. no. 202IL010CF). 2.3. Relative Viability GBM xenograft and syngeneic cells were seeded in 96 well plates at densities

(7) Refined analytical pipeline for the pharmacodynamic assessment of T-cell responses to vaccine antigensFrontiers in ImmunologyApril 24, 2024Michail Angelos Pavlidis, Nadia Viborg, Mads Lausen, Birgitte Rønø, Daniela Kleine-KohlbrecherCO2). On day 3, culture medium was prepared, supplemented with 120 U/ml of IL-2 (R&D Systems, cat. #202-IL-010/CF), before distribution of 0.5 ml medium into each well, resulting in a new total volume of 1.5 ml/well.

(8) Protocol for lentiviral vector-based gene transfection in human ILC2sSTAR ProtocolsMarch 15, 2024Misato Irie, Hiroki Kabata, Koichi FukunagaBio,Cat#6194 Forskolin,Sigma-Aldrich,Cat#F3917 Lenti-X concentrator,Takara Bio,Cat#631231 Recombinant human IL-2 protein,R&D Systems,Cat#202-IL-010/CF Recombinant human IL-33 protein,R&D Systems,Cat#3625-IL-010/CF RPMI-1640,Gibco,Cat#C11875 FBS,MP

(9) The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formationeLifeDecember 21, 2023Wheeler BD, Gagnon JD, Zhu WS, Muñoz-Sandoval P, Wong SK, Simeonov DS, Li Z, DeBarge R, Spitzer MH, Marson A, et al.kool aid complete media for 2 days supplemented with 100 U/ml recombinant Human IL-2 (R&D Systems Cat# 202-IL-010/CF). Subsequently, 1 × 106 cells were used to prepare NGS libraries as described in Gagnon and Ansel, 2019

(10) Characterization of CAR T Cells Manufactured Using Genetically Engineered Artificial Antigen Presenting CellsCell JOctober 9, 2023Ali Sayadmanesh, Mohammad Azadbakht, Kheirollah Yari, Ali Abedelahi, Hajar Shafaei, Dariush Shanehbandi, Behzad Baradaran, Mohsen Basiri1:0.5, and 1:0.25, respectively. On day 1, CTL medium containing 100 IU/ml human IL-2 (R, 202-IL-010/CF) was added to the plates and T cell expansion continued. Every two days, the cells were counted with

(11) Characterization of CAR T Cells Manufactured Using Genetically Engineered Artificial Antigen Presenting CellsCell JOctober 9, 2023Ali Sayadmanesh, Mohammad Azadbakht, Kheirollah Yari, Ali Abedelahi, Hajar Shafaei, Dariush Shanehbandi, Behzad Baradaran, Mohsen Basiri1:0.5, and 1:0.25, respectively. On day 1, CTL medium containing 100 IU/ml human IL-2 (R, 202-IL-010/CF) was added to the plates and T cell expansion continued. Every two days, the cells were counted with

(12) Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cellsCell reportsAugust 29, 2023Le Moine M, Azouz A, Sanchez Sanchez G, Dejolier S, Nguyen M, Thomas S, Shala V, Dreidi H, Denanglaire S, Libert F, et al.

(13) Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2sCell reportsJune 27, 2023Irie M, Kabata H, Sasahara K, Kurihara M, Shirasaki Y, Kamatani T, Baba R, Matsusaka M, Koga S, Masaki K, et al.

(14) ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathwaybioRxiv : the preprint server for biologyApril 3, 2023Anannya O, Huang W, August A.

(15) Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive TumorsBiomoleculesMarch 2, 2023Silva G, Rodrigues AF, Ferreira S, Matos C, Eleutério RP, Marques G, Kucheryava K, Lemos AR, Sousa PMF, Castro R, et al.

(16) Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell TherapyBiomedicinesFebruary 4, 2023Beck C, Casey NP, Persiconi I, Moharrami NN, Sike A, Jin Y, Kyte JA.

(17) Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variantsCell reportsJanuary 31, 2023Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai KZ, Madssen TS, Vaage JT, Gustavsen A, et al.

(18) An αvβ3 integrin checkpoint is critical for efficient T(H)2 cell cytokine polarization and potentiation of antigen-specific immunityNature immunologyJanuary 1, 2023Szeto ACH, Ferreira ACF, Mannion J, Clark PA, Sivasubramaniam M, Heycock MWD, Crisp A, Jolin HE, Kozik P, Knolle MD, et al.

(19) SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2DCell reportsDecember 27, 2022Lee MJ, Leong MW, Rustagi A, Beck A, Zeng L, Holmes S, Qi LS, Blish CA.

(20) Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma IrradiationVirusesDecember 23, 2022Boytz R, Seitz S, Gaudiano E, Patten JJ, Keiser PT, Connor JH, Sharpe AH, Davey RA.

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Recombinant Human IL-2 Protein, CF from R&D Systems, a Bio-Techne Brand

Supplier Page View Company Product Page$269.00

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Recombinant Human IL-2 Protein, CF

IL-2 Protein

IL-2 Protein

IL-2 Protein

IL-2 Protein

Recombinant Human IL-2 Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

Citations (380)

Reviews

Recombinant Human IL-2 Protein, CF from R&D Systems, a Bio-Techne Brand

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